Results 1 to 10 of about 39,607,185 (297)

The antagonistic pleiotropy of insulin‐like growth factor 1 [PDF]

Aging Cell, 2021
AbstractWhile insulin‐like growth factor‐1 (IGF‐1) is a well‐established modulator of aging and longevity in model organisms, its role in humans has been controversial. In this study, we used the UK Biobank (n = 440,185) to resolve previous ambiguities in the relationship between serum IGF‐1 levels and clinical disease.
William B. Zhang, Kenny Ye, Nir Barzilai, Sofiya Milman   +3 more
openaire   +2 more sources

Insulin Like Growth Factor Binding Protein 7 as a Novel Diagnostic Marker in Sera of Iraqi Patients with Acromegaly

مجلة بغداد للعلوم, 2023
The purpose of this study was to measure serum levels of insulin-like growth factor-binding protein (IGFBP7), Insulin-like Growth Factor 1 (IGF-1), Growth Hormone (GH), Interleukin 6 (IL-6) and insulin in acromegaly patients and healthy controls.
Layla Othman Farhan, Baydaa Ahmed Abed, Kashtl Ghasaq J., Isam Noori Salman   +3 more
doaj   +1 more source

Molecular Characterization and Expression Analysis of Insulin-like Growth Factor-1 and Insulin-like Growth Factor Binding Protein-1 Genes in Qinghai-Tibet Plateau and Lowland [PDF]

Asian-Australasian Journal of Animal Sciences, 2015
Insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-1 (IGFBP-1) play a pivotal role in regulating cellular hypoxic response.
Ya-bing Chen, Mei Fu, Dao-liang Lan, Jian Li   +3 more
doaj   +1 more source

Insulin-like Growth Factor-1 [PDF]

Current Opinion in Gastroenterology, 2012
Strange, disturbing quality to subjects’ dream life. Difficulty concentrating. Headache in the forehead. Nasal congestion. Cramping abdominal pain associated with diarrhea or stool. Constipation with ineffectual urging. Strong uterine cramping with the menses. Premenstrual breast tenderness and swelling. Nausea. An aversion to chocolate and sweets.
Sarah F, Bortvedt, P Kay, Lund
openaire   +3 more sources

Cloning and expression of full-length human insulin-like growth factor binding protein 3 (IGFBP3) in the Escherichia coli

Advanced Biomedical Research, 2015
Background: The effect of the growth hormone on target cells is mediated by the insulin-like growth factor 1 (IGF-1). IGF-1 binds to the insulin-like growth factor binding proteins (IGFBPs) in blood and biological fluids.
Emad Khodadadi, Mojtaba Panjepour, Mahdi Abbasian, Zahra Khalili Broujeni, Mohammad Reza Mofid   +4 more
doaj   +1 more source

Microgravity, Bone Homeostasis, and Insulin-Like Growth Factor-1

Applied Sciences, 2020
Astronauts at are risk of losing 1.0–1.5% of their bone mass for every month they spend in space despite their adherence to high impact exercise training programs and diets high in nutrients, potassium, calcium, and vitamin D, all designed to preserve ...
John Kelly Smith
doaj   +1 more source

Changes in Insulin-like Growth Factor-1 Level in Patients with Sepsis and Septic Shock [PDF]

Korean Journal of Critical Care Medicine, 2016
Background Despite many ongoing, prospective studies on the topic, sepsis still remains one of the main causes of death in hospital. The hormone insulin-like growth factor 1 (IGF-1) has a similar molecular structure to that of insulin.
Sang Hoon Lee, Byung Hoon Park, Joo Han Song, Song Yee Kim, Kyung Soo Chung, Eun Young Kim, Ji Ye Jung, Young Sam Kim, Se Kyu Kim, Joon Chang, Moo Suk Park   +10 more
doaj   +1 more source

Insulin-like Growth Factor 1 Signaling in Mammalian Hearing [PDF]

Genes, 2021
Insulin-like growth factor 1 (IGF-1) is a peptide hormone belonging to the insulin family of proteins. Almost all of the biological effects of IGF-1 are mediated through binding to its high-affinity tyrosine kinase receptor (IGF1R), a transmembrane receptor belonging to the insulin receptor family.
Ángela García-Mato, Blanca Cervantes, Silvia Murillo-Cuesta, Lourdes Rodríguez-de la Rosa, Isabel Varela-Nieto   +4 more
openaire   +4 more sources

Insulin-like growth factor 1 and hair growth

Dermatology Online Journal, 1999
Insulin-like growth factor 1 (IGF-1) has been identified as an important growth factor in many biological systems.[1] It shares considerable structural homology with insulin and exerts insulin-like effects on food intake and glucose metabolism. Recently it has been suggested to play a role in regulating cellular proliferation and migration during the ...
Su, Hung-Yi, Hickford, Jonathan G H, Palmer, Barry R, Bickerstaffe, Roy   +3 more
openaire   +4 more sources

Heart Smart Insulin-Like Growth Factor 1 [PDF]

Hypertension, 2012
See related article, pp 680–693 The prevalence of obesity, metabolic syndrome, and type 2 diabetes mellitus, and the associated cardiac pathologies are rising to alarming levels. Conventional medical therapies for the prevention and treatment of cardiomyopathy are less effective in patients with these metabolic disorders, and this is attributed, at ...
Marsh, Susan A, Davidoff, Amy J
openaire   +3 more sources