Results 11 to 20 of about 113,369,369 (332)

Doxorubicin impairs the insulin-like growth factor-1 system and causes insulin-like growth factor-1 resistance in cardiomyocytes. [PDF]

PLoS ONE, 2015
Insulin-like growth factor-1 (IGF-1) promotes the survival of cardiomyocytes by activating type 1 IGF receptor (IGF-1R). Within the myocardium, IGF-1 action is modulated by IGF binding protein-3 (IGFBP-3), which sequesters IGF-1 away from IGF-1R.
Patrizia Fabbi, Paolo Spallarossa, Silvano Garibaldi, Chiara Barisione, Marzia Mura, Paola Altieri, Barbara Rebesco, Maria Gaia Monti, Marco Canepa, Giorgio Ghigliotti, Claudio Brunelli, Pietro Ameri   +11 more
doaj   +6 more sources

Insulin-Like Growth Factor-1 and Neuroinflammation [PDF]

Frontiers in Aging Neuroscience, 2017
Insulin-like growth factor-1 (IGF-1) effects on aging and neurodegeneration is still controversial. However, it is widely admitted that IGF-1 is involved in the neuroinflammatory response.
Jose L. Labandeira-Garcia, Jose L. Labandeira-Garcia, Maria A. Costa-Besada, Maria A. Costa-Besada, Carmen M. Labandeira, Begoña Villar-Cheda, Begoña Villar-Cheda, Ana I. Rodríguez-Perez, Ana I. Rodríguez-Perez   +8 more
doaj   +3 more sources

In silico interaction of insulin-like growth factor binding protein 3 with insulin-like growth factor 1

Research in Pharmaceutical Sciences, 2018
Insulin-like growth factor binding protein-3 (IGFBP-3) is a vital protein exist in circulation which interacts with high affinity to insulin-like growth factor (IGFs) altering their activities.
Elham Jafari, Ali Gheysarzadeh, Karim Mahnam, Rezvan Shahmohammadi, Amir Ansari, Hadi Bakhtyari, Mohammad Reza Mofid   +6 more
doaj   +4 more sources

Adult growth hormone deficiency treatment with a combination of growth hormone and insulin-like growth factor-1 resulting in elevated sustainable insulin-like growth factor-1 and insulin-like growth factor binding protein 3 plasma levels: a case report [PDF]

Journal of Medical Case Reports, 2010
Introduction Adult Growth hormone Deficiency is a well known phenomenon effecting both males and females. Adult Growth Hormone Deficiency is marked by a number of neuropsychiatric, cognitive performance, cardiac, metabolic, muscular, and bone symptoms ...
Madigan Margaret, Chen Thomas JH, Yeldandi Swetha, Damle Uma J, Bowirrat Abdalla, Braverman Eric R, Kerner Mallory, Huang Stanley X, Savarimuthu Stella, Blum Kenneth   +9 more
doaj   +3 more sources

Associations of insulin and insulin-like growth factors with physical performance in old age in the boyd orr and caerphilly studies. [PDF]

, 2012
OBJECTIVE: Insulin and the insulin-like growth factor (IGF) system regulate growth and are involved in determining muscle mass, strength and body composition.
David Gunnell, Gunnell, David, Gallacher, John, Martin, Richard M., Birnie, K, Gunnell, D, Kate Birnie, Gunnell David, Antony Bayer, Bayer Antony, John Gallacher, Ebrahim, S, Holly, Jeff MP, Bayer, A, Yoav Ben-Shlomo, Birnie Kate, Shah Ebrahim, Ben-Shlomo, Y, Ebrahim, Shah, Jeff M P Holly, Gunnell, DJ, Gallacher, J, Martin, Richard M, Holly, JM, Bayer, Antony, Jeff M. P. Holly, Martin Richard M., Martin, RM, Richard M Martin, Richard M. Martin, Holly Jeff M. P., Gallacher John, Holly, JMP, Holly, Jeff M. P., Bayer, Antony James, Birnie, Kate, Ben-Shlomo, Yoav, Ben-Shlomo Yoav, Ebrahim Shah, Gallacher, John Edward   +39 more
core   +5 more sources

Insulin-like growth factor-1 and zinc

Turkish Journal of Hematology, 2008
Nejat Akar
doaj   +2 more sources

Divergent skeletal muscle metabolite exchange in insulin-like growth factor-1-stimulated myotubes and resistance-exercised human muscle. [PDF]

Exp Physiol
Havers T, Eggelbusch M, Meinhold M, Sing K, Okrojek R, Artati A, Witting M, Lutter D, Kieker CV, Starke C, More T, Hiller K, Dela F, Schönfelder M, Kafka A, Geisler S, Wackerhage H.   +16 more
europepmc   +2 more sources

Serum insulin-like growth factor-1 concentrations are not reduced in Pomeranian dogs with Alopecia X: a case-control study. [PDF]

BMC Vet Res
Halajian Z, Khoshnegah J, Parham A.
europepmc   +2 more sources

The antagonistic pleiotropy of insulin‐like growth factor 1 [PDF]

Aging Cell, 2021
AbstractWhile insulin‐like growth factor‐1 (IGF‐1) is a well‐established modulator of aging and longevity in model organisms, its role in humans has been controversial. In this study, we used the UK Biobank (n = 440,185) to resolve previous ambiguities in the relationship between serum IGF‐1 levels and clinical disease.
William B. Zhang, Kenny Ye, Nir Barzilai, Sofiya Milman   +3 more
openaire   +2 more sources

Insulin-Like Growth Factor-1 as a Vascular Protective Factor [PDF]

Circulation, 2004
Recent advances in cardiology have focused on proliferation and regeneration as potential cardiovascular defense mechanisms. Within this framework, growth factors are acquiring increasing importance; insulin-like growth factor-1 (IGF-1) emerges among them for its versatile pleiotropic actions.
E. Conti, C. Carrozza, E. Capoluongo, VOLPE, Massimo, F. Crea, C. Zuppi, F. Andreotti   +6 more
openaire   +3 more sources