Results 11 to 20 of about 39,607,185 (297)

Insulin-Like Growth Factor-1 and Neuroinflammation [PDF]

Frontiers in Aging Neuroscience, 2017
Insulin-like growth factor-1 (IGF-1) effects on aging and neurodegeneration is still controversial. However, it is widely admitted that IGF-1 is involved in the neuroinflammatory response.
Jose L. Labandeira-Garcia, Jose L. Labandeira-Garcia, Maria A. Costa-Besada, Maria A. Costa-Besada, Carmen M. Labandeira, Begoña Villar-Cheda, Begoña Villar-Cheda, Ana I. Rodríguez-Perez, Ana I. Rodríguez-Perez   +8 more
doaj   +3 more sources

Doxorubicin impairs the insulin-like growth factor-1 system and causes insulin-like growth factor-1 resistance in cardiomyocytes. [PDF]

PLoS ONE, 2015
Insulin-like growth factor-1 (IGF-1) promotes the survival of cardiomyocytes by activating type 1 IGF receptor (IGF-1R). Within the myocardium, IGF-1 action is modulated by IGF binding protein-3 (IGFBP-3), which sequesters IGF-1 away from IGF-1R.
Patrizia Fabbi, Paolo Spallarossa, Silvano Garibaldi, Chiara Barisione, Marzia Mura, Paola Altieri, Barbara Rebesco, Maria Gaia Monti, Marco Canepa, Giorgio Ghigliotti, Claudio Brunelli, Pietro Ameri   +11 more
doaj   +6 more sources

Insulin-like growth factor-1/insulin-like growth factor-1 receptor signalling in macrophages facilitates recovery from acute lung injury [PDF]

Annals of Medicine
Background No effective treatment strategy for acute respiratory distress syndrome (ARDS) has been established. Conflicting reports on the effects of insulin-like growth factor (IGF)-1 stimulation and the inhibition of IGF-1 receptor (IGF-1R) signalling ...
Miyuki Niisato, Masahiro Yamashita, Yasushi Kawasaki, Hiroshi Furukawa, Takashi Sato, Ichiro Kawada   +5 more
doaj   +2 more sources

In silico interaction of insulin-like growth factor binding protein 3 with insulin-like growth factor 1

Research in Pharmaceutical Sciences, 2018
Insulin-like growth factor binding protein-3 (IGFBP-3) is a vital protein exist in circulation which interacts with high affinity to insulin-like growth factor (IGFs) altering their activities.
Elham Jafari, Ali Gheysarzadeh, Karim Mahnam, Rezvan Shahmohammadi, Amir Ansari, Hadi Bakhtyari, Mohammad Reza Mofid   +6 more
doaj   +4 more sources

Interoceptive Information of Physical Vigor Through Circulating Insulin‐Like Growth Factor 1 [PDF]

FASEB BioAdvances
The brain relies on interoceptive feedback signals to regulate bodily functions. Female mice with low serum IGF‐1 levels (LID mice) exhibit reduced spontaneous running compared to control females, an effect not seen in males.
Jonathan A. Zegarra‐Valdivia, M. Zahid Khan, Jansen Fernandes, Kentaro Suda, M. Estrella Fernandez deSevilla, Sonia Díaz‐Pacheco, Ignacio Torres Aleman   +6 more
doaj   +2 more sources

Insulin-like growth factor binding protein-1 at the maternal-fetal interface and insulin-like growth factor-I, insulin-like growth factor-II, and insulin-like growth factor binding protein-1 in the circulation of women with severe preeclampsia

American Journal of Obstetrics and Gynecology, 1997
Preeclampsia is characterized by maternal hypertension, proteinuria, edema, and shallow placental invasion. Insulin-like growth factor binding protein-1, abundant in maternal decidua, is believed to play a role in limiting trophoblast invasiveness.
Maurice Druzin, Linda Giudice, M Druzin   +2 more
exaly   +3 more sources

The signaling landscape of insulin-like growth factor 1. [PDF]

J Biol Chem
The sheer amplitude of biological actions of insulin-like growth factor I (IGF-1) affecting all types of cells in all tissues suggests a vast signaling landscape for this ubiquitous humoral signal. While the canonical signaling pathways primarily involve the Ras/MAPK and PI3K/AKT cascades, the evolutionary conservation of insulin-like peptides (ILPs ...
Khan MZ, Zugaza JL, Torres Aleman I.
europepmc   +3 more sources

Associations of insulin and insulin-like growth factors with physical performance in old age in the boyd orr and caerphilly studies. [PDF]

, 2012
OBJECTIVE: Insulin and the insulin-like growth factor (IGF) system regulate growth and are involved in determining muscle mass, strength and body composition.
David Gunnell, Gunnell, David, Gallacher, John, Martin, Richard M., Birnie, K, Gunnell, D, Kate Birnie, Gunnell David, Antony Bayer, Bayer Antony, John Gallacher, Ebrahim, S, Holly, Jeff MP, Bayer, A, Yoav Ben-Shlomo, Birnie Kate, Shah Ebrahim, Ben-Shlomo, Y, Ebrahim, Shah, Jeff M P Holly, Gunnell, DJ, Gallacher, J, Martin, Richard M, Holly, JM, Bayer, Antony, Jeff M. P. Holly, Martin Richard M., Martin, RM, Richard M Martin, Richard M. Martin, Holly Jeff M. P., Gallacher John, Holly, JMP, Holly, Jeff M. P., Bayer, Antony James, Birnie, Kate, Ben-Shlomo, Yoav, Ben-Shlomo Yoav, Ebrahim Shah, Gallacher, John Edward   +39 more
core   +5 more sources

Insulin-like growth factor-1 and zinc

Turkish Journal of Hematology, 2008
Nejat Akar
doaj   +2 more sources

Correlation of Insulin Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein with LH, FSH and Testosterone in Iraqi Children with Growth Hormone Deficiency

Iraqi Journal of Chemical and Petroleum Engineering, 2023
Insulin like growth factor-1 has metabolic and growth-related roles all over the body and is strongly associated and regulated by growth hormone. It is produced by almost any type of tissue, especially the liver.
Athraa F. Hasan, Bushra F. Hassan, ABDILKAREEM Y. AL-SAMERAIE   +2 more
doaj   +1 more source