Results 11 to 20 of about 346,512 (160)

In silico interaction of insulin-like growth factor binding protein 3 with insulin-like growth factor 1

open access: yesResearch in Pharmaceutical Sciences, 2018
Insulin-like growth factor binding protein-3 (IGFBP-3) is a vital protein exist in circulation which interacts with high affinity to insulin-like growth factor (IGFs) altering their activities.
Elham Jafari   +6 more
doaj   +4 more sources

The antagonistic pleiotropy of insulin‐like growth factor 1 [PDF]

open access: yesAging Cell, 2021
AbstractWhile insulin‐like growth factor‐1 (IGF‐1) is a well‐established modulator of aging and longevity in model organisms, its role in humans has been controversial. In this study, we used the UK Biobank (n = 440,185) to resolve previous ambiguities in the relationship between serum IGF‐1 levels and clinical disease.
William B. Zhang   +3 more
openaire   +2 more sources

Insulin-Like Growth Factor-1 as a Vascular Protective Factor [PDF]

open access: yesCirculation, 2004
Recent advances in cardiology have focused on proliferation and regeneration as potential cardiovascular defense mechanisms. Within this framework, growth factors are acquiring increasing importance; insulin-like growth factor-1 (IGF-1) emerges among them for its versatile pleiotropic actions.
E. Conti   +6 more
openaire   +3 more sources

Insulin-like Growth Factor-1 [PDF]

open access: yesCurrent Opinion in Gastroenterology, 2012
Strange, disturbing quality to subjects’ dream life. Difficulty concentrating. Headache in the forehead. Nasal congestion. Cramping abdominal pain associated with diarrhea or stool. Constipation with ineffectual urging. Strong uterine cramping with the menses. Premenstrual breast tenderness and swelling. Nausea. An aversion to chocolate and sweets.
Sarah F, Bortvedt, P Kay, Lund
openaire   +3 more sources

Heart Smart Insulin-Like Growth Factor 1 [PDF]

open access: yesHypertension, 2012
See related article, pp 680–693 The prevalence of obesity, metabolic syndrome, and type 2 diabetes mellitus, and the associated cardiac pathologies are rising to alarming levels. Conventional medical therapies for the prevention and treatment of cardiomyopathy are less effective in patients with these metabolic disorders, and this is attributed, at ...
Marsh, Susan A, Davidoff, Amy J
openaire   +3 more sources

Insulin-like Growth Factor 1 Signaling in Mammalian Hearing [PDF]

open access: yesGenes, 2021
Insulin-like growth factor 1 (IGF-1) is a peptide hormone belonging to the insulin family of proteins. Almost all of the biological effects of IGF-1 are mediated through binding to its high-affinity tyrosine kinase receptor (IGF1R), a transmembrane receptor belonging to the insulin receptor family.
Ángela García-Mato   +4 more
openaire   +4 more sources

Changes in Insulin-like Growth Factor-1 Level in Patients with Sepsis and Septic Shock [PDF]

open access: yesKorean Journal of Critical Care Medicine, 2016
Background Despite many ongoing, prospective studies on the topic, sepsis still remains one of the main causes of death in hospital. The hormone insulin-like growth factor 1 (IGF-1) has a similar molecular structure to that of insulin.
Sang Hoon Lee   +10 more
doaj   +1 more source

Insulin-like growth factor 1 and hair growth

open access: yesDermatology Online Journal, 1999
Insulin-like growth factor 1 (IGF-1) has been identified as an important growth factor in many biological systems.[1] It shares considerable structural homology with insulin and exerts insulin-like effects on food intake and glucose metabolism. Recently it has been suggested to play a role in regulating cellular proliferation and migration during the ...
Su, Hung-Yi   +3 more
openaire   +4 more sources

IGF-Binding Proteins: Why Do They Exist and Why Are There So Many?

open access: yesFrontiers in Endocrinology, 2018
Insulin-like growth factors (IGFs) are key growth-promoting peptides that act as both endocrine hormones and autocrine/paracrine growth factors. In the bloodstream and in local tissues, most IGF molecules are bound by one of the members of the IGF ...
John B. Allard, Cunming Duan
doaj   +1 more source

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