Iraqi Journal of Chemical and Petroleum Engineering, 2023 Insulin like growth factor-1 has metabolic and growth-related roles all over the body and is strongly associated and regulated by growth hormone. It is produced by almost any type of tissue, especially the liver.
Athraa F. Hasan +2 more
doaj +1 more source
Doxorubicin impairs the insulin-like growth factor-1 system and causes insulin-like growth factor-1 resistance in cardiomyocytes. [PDF]
PLoS ONE, 2015 Insulin-like growth factor-1 (IGF-1) promotes the survival of cardiomyocytes by activating type 1 IGF receptor (IGF-1R). Within the myocardium, IGF-1 action is modulated by IGF binding protein-3 (IGFBP-3), which sequesters IGF-1 away from IGF-1R.
Patrizia Fabbi +11 more
doaj +1 more source
مجلة بغداد للعلوم, 2023 The purpose of this study was to measure serum levels of insulin-like growth factor-binding protein (IGFBP7), Insulin-like Growth Factor 1 (IGF-1), Growth Hormone (GH), Interleukin 6 (IL-6) and insulin in acromegaly patients and healthy controls.
Layla Othman Farhan +3 more
doaj +1 more source
Molecular Characterization and Expression Analysis of Insulin-like Growth Factor-1 and Insulin-like Growth Factor Binding Protein-1 Genes in Qinghai-Tibet Plateau and Lowland [PDF]
Asian-Australasian Journal of Animal Sciences, 2015 Insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-1 (IGFBP-1) play a pivotal role in regulating cellular hypoxic response.
Ya-bing Chen +3 more
doaj +1 more source
Analysis of the Effects of Five Factors Relevant to In Vitro Chondrogenesis of Human Mesenchymal Stem Cells Using Factorial Design and High Throughput mRNA-Profiling [PDF]
, 2014 The in vitro process of chondrogenic differentiation of mesenchymal stem cells for tissue engineering has been shown to require three-dimensional culture along with the addition of differentiation factors to the culture medium.
Brinchmann, Jan E. +4 more
core +10 more sources
Advanced Biomedical Research, 2015 Background: The effect of the growth hormone on target cells is mediated by the insulin-like growth factor 1 (IGF-1). IGF-1 binds to the insulin-like growth factor binding proteins (IGFBPs) in blood and biological fluids.
Emad Khodadadi +4 more
doaj +1 more source
Pasireotide for the Medical Management of Feline Hypersomatotropism [PDF]
, 2015 BACKGROUND: Feline hypersomatotropism (HST) is a cause of diabetes mellitus in cats. Pasireotide is a novel multireceptor ligand somatostatin analog that improves biochemical control of humans with HST.
Abraham +45 more
core +2 more sources
Insulin-Like Growth Factor-1 and Neuroinflammation
Frontiers in Aging Neuroscience, 2017 Insulin-like growth factor-1 (IGF-1) effects on aging and neurodegeneration is still controversial. However, it is widely admitted that IGF-1 is involved in the neuroinflammatory response.
Jose L. Labandeira-Garcia +8 more
doaj +1 more source
Microgravity, Bone Homeostasis, and Insulin-Like Growth Factor-1
Applied Sciences, 2020 Astronauts at are risk of losing 1.0–1.5% of their bone mass for every month they spend in space despite their adherence to high impact exercise training programs and diets high in nutrients, potassium, calcium, and vitamin D, all designed to preserve ...
John Kelly Smith
doaj +1 more source
Changes in Insulin-like Growth Factor-1 Level in Patients with Sepsis and Septic Shock [PDF]
Korean Journal of Critical Care Medicine, 2016 Background Despite many ongoing, prospective studies on the topic, sepsis still remains one of the main causes of death in hospital. The hormone insulin-like growth factor 1 (IGF-1) has a similar molecular structure to that of insulin.
Sang Hoon Lee +10 more
doaj +1 more source