Results 221 to 230 of about 49,296 (268)
Some of the next articles are maybe not open access.
Pituitary, 2006
Acromegaly is a slowly progressive disease characterized by 30% increase of mortality rate for cardiovascular disease, respiratory complications and malignancies. The estimated prevalence of the disease is 40 cases/1000000 population with 3-4 new cases/1000000 population per year.
M. Scacchi, F. Cavagnini
openaire +2 more sources
Acromegaly is a slowly progressive disease characterized by 30% increase of mortality rate for cardiovascular disease, respiratory complications and malignancies. The estimated prevalence of the disease is 40 cases/1000000 population with 3-4 new cases/1000000 population per year.
M. Scacchi, F. Cavagnini
openaire +2 more sources
Endocrinology and Metabolism Clinics of North America, 1992
Ectopic acromegaly is a rare syndrome (less than 1% of acromegalic patients) caused by ectopic growth hormone-releasing hormone (GHRH) or growth hormone (GH)-producing tumors. Its recognition is clinically important because acromegaly may be a symptom of an aggressive tumor, and different therapeutic approaches are required.
G. Faglia, M. Arosio, N. Bazzoni
openaire +3 more sources
Ectopic acromegaly is a rare syndrome (less than 1% of acromegalic patients) caused by ectopic growth hormone-releasing hormone (GHRH) or growth hormone (GH)-producing tumors. Its recognition is clinically important because acromegaly may be a symptom of an aggressive tumor, and different therapeutic approaches are required.
G. Faglia, M. Arosio, N. Bazzoni
openaire +3 more sources
Growth Hormone & IGF Research, 2004
Most pituitary tumors are sporadic, though a few occur with a familial aggregation. Three distinct syndromes have been recognized to date: multiple endocrine neoplasia, type I (MEN-1), Carney complex (CNC), and isolated familial somatotropinomas (IFS). Pituitary tumor types in MEN-1 are similar to those occurring sporadically.
Lawrence A, Frohman, Kuniki, Eguchi
openaire +2 more sources
Most pituitary tumors are sporadic, though a few occur with a familial aggregation. Three distinct syndromes have been recognized to date: multiple endocrine neoplasia, type I (MEN-1), Carney complex (CNC), and isolated familial somatotropinomas (IFS). Pituitary tumor types in MEN-1 are similar to those occurring sporadically.
Lawrence A, Frohman, Kuniki, Eguchi
openaire +2 more sources
Acta Endocrinologica, 1989
Abstract. Five family members over 3 generations had isolated functional pituitary adenomas diagnosed. In four cases acromegaly was diagnosed, and in the fifth galactorrhoea from prolactin excess was the presenting feature. A prominent feature of the affected members tumours were histological finding of either atypical mixed cell or undifferentiated ...
R G, Pestell, F P, Alford, J D, Best
openaire +2 more sources
Abstract. Five family members over 3 generations had isolated functional pituitary adenomas diagnosed. In four cases acromegaly was diagnosed, and in the fifth galactorrhoea from prolactin excess was the presenting feature. A prominent feature of the affected members tumours were histological finding of either atypical mixed cell or undifferentiated ...
R G, Pestell, F P, Alford, J D, Best
openaire +2 more sources
2014
Acromegaly is due to excessive production of growth hormone (GH), generally by a pituitary GH-secreting adenoma. Its prevalence is estimated at 40-130 cases per million inhabitants. Acromegaly is characterized by slowly progressive acquired somatic disfigurement (mainly involving the face and extremities) and systemic manifestations. The rheumatologic,
Philippe, Chanson +2 more
openaire +2 more sources
Acromegaly is due to excessive production of growth hormone (GH), generally by a pituitary GH-secreting adenoma. Its prevalence is estimated at 40-130 cases per million inhabitants. Acromegaly is characterized by slowly progressive acquired somatic disfigurement (mainly involving the face and extremities) and systemic manifestations. The rheumatologic,
Philippe, Chanson +2 more
openaire +2 more sources
Clinical Endocrinology, 1984
SUMMARYAn uncle and nephew with acromegaly are described. Two other families with acromegaly have been reported by others and three other possible cases are reviewed. Our patients are unlikely to form part of the multiple endocrine neoplasia (MEN) type 1 syndrome because of the absence of other endocrine disease at an advanced age.
M K, Jones +3 more
openaire +2 more sources
SUMMARYAn uncle and nephew with acromegaly are described. Two other families with acromegaly have been reported by others and three other possible cases are reviewed. Our patients are unlikely to form part of the multiple endocrine neoplasia (MEN) type 1 syndrome because of the absence of other endocrine disease at an advanced age.
M K, Jones +3 more
openaire +2 more sources
Drugs, 1994
Acromegaly is a chronic debilitating disease caused by growth hormone (GH) hypersecretion, usually from a pituitary adenoma. It is frequently diagnosed after many years of active GH hypersecretion, and causes significant morbidity and mortality due to cardiac, pulmonary and musculoskeletal changes.
C A, Jaffe, A L, Barkan
openaire +2 more sources
Acromegaly is a chronic debilitating disease caused by growth hormone (GH) hypersecretion, usually from a pituitary adenoma. It is frequently diagnosed after many years of active GH hypersecretion, and causes significant morbidity and mortality due to cardiac, pulmonary and musculoskeletal changes.
C A, Jaffe, A L, Barkan
openaire +2 more sources
Endocrinology and Metabolism Clinics of North America, 1991
Acromegaly may result from ectopic production of the hypothalamic peptide, growth hormone releasing hormone (GHRH), or growth hormone (GH) itself. Hypothalamic, carcinoid, and pancreatic tumors account for most of these cases. The pathogenesis, etiology, and diagnosis of acromegaly caused by these nonpituitary tumors is discussed, and an approach to ...
openaire +2 more sources
Acromegaly may result from ectopic production of the hypothalamic peptide, growth hormone releasing hormone (GHRH), or growth hormone (GH) itself. Hypothalamic, carcinoid, and pancreatic tumors account for most of these cases. The pathogenesis, etiology, and diagnosis of acromegaly caused by these nonpituitary tumors is discussed, and an approach to ...
openaire +2 more sources
Modern approach to resistant acromegaly
Endocrine, 2023A. Giustina +3 more
semanticscholar +1 more source