Results 131 to 140 of about 8,172 (292)

Coordination of Cyanobacterial Nitrate Assimilation and Photosynthesis by a Novel PsbO‐Interacting Protein PirN

Advanced Science, EarlyView.
PirN was identified as a previously uncharacterized PsbO‐interacting protein specifically induced in nitrate‐grown cyanobacteria. Loss of PirN leads to coordinated downregulation of PsbO and the nitrate reductase NarB, causing decreased PSII activity and impaired growth under nitrate conditions. Complementation with either PsbO or NarB largely restores
Chengcheng Huang, Zhen Xiao, Haitao Ge, Gaojie Wang, Jinghui Dong, Yan Wang, Hang Yang, Xing Wang, Hui Gao, Zhongshu Wang, Huanling Yang, Yuanya Zhang, Xiahe Huang, Wu Xu, Weimin Ma, Wenqiang Yang, Yingchun Wang   +16 more
wiley   +1 more source

Efficient synthesis and RAFT polymerization of the previously elusive N -[(cycloalkylamino)methyl]acrylamide monomer class [PDF]

, 2017
Abel, Abel, Baltieri, Böhme, Böhme, Eritsyan, Gody, Gody, Heaney, Jenkins, Li, Li, Magee, Müller, Müller, Porzelle, Wang, Zhou, Zhu   +18 more
core   +1 more source

Michael–type reactions of β-nitrostyrenes with piperidine: effect of solvents on reactivity and reaction mechanism [PDF]

, 2014
Present report deals with the effect of solvent on the kinetics and mechanism of Michael-type reaction of ƒÒ-nitrostyrene with piperidine. Three different types of solvents are used for the study namely, nonpolar (chloroform, toluene, hexane), dipolar ...
Meher, Sameer Kumar, Sahu, Tushar Kanta
core  

Development and Structural Characterization of UTE‐156, a Covalent Inhibitor of the VCP/p97 AAA+ ATPase

Advanced Science, EarlyView.
The AAA+ ATPase Valosin‐containing protein (VCP/p97) regulates protein homeostasis by unfolding ubiquitinated substrates. Here, we describe UTE‐156, a novel irreversible covalent inhibitor that modifies Cys522 in the D2 ATPase motor domain. Although its pharmacochemical limitations preclude immediate therapeutic use, UTE‐156 serves as a valuable ...
Daniela Tamayo‐Jaramillo, Subramanya Hegde, Xuan Jia, Kimberly Coffman, Hariprasad Vankayalapati, David Bearss, Kevin B. Jones, Alex W. Stark, Peter S. Shen   +8 more
wiley   +1 more source

Sulfur-and selenium-targeting warheads: reaction-based design of electrophilic warheads for selective inhibition of enzyme

Frontiers in Chemistry
Covalent inhibitors for nucleophilic residues, particularly cysteine (Cys) and selenocysteine (Sec), have resurfaced as precision therapies for modifying disease-associated enzymes.
Neha Jain, Michio Iwaoka, Michio Iwaoka
doaj   +1 more source

Printable Conductive Hydrogels for Electrochemical Biosensing and Soft Bioelectronic Interfaces

Advanced Science, EarlyView.
Flexible, conductive hydrogels that integrate printability, mechanical tunability, biocompatibility, and electronic performance remain challenging to achieve. Here, we develop 3D‐printable poly(ethylene glycol)–poly(pyrrole)‐ hydrogels with tissue‐like mechanics, high cytocompatibility, and robust electrochemical function.
Lukas Hein, Renan Colucci, Xin Wei, Tsvetomir Ivanov, Katharina Landfester, Ulrike Kraft, Maria Villiou   +6 more
wiley   +1 more source

ACRYLAMIDE

Acta Crystallographica Section E Structure Reports Online, 2007
Qing-Li Zhou, Zhen-Heng Zhang, Zuo-Liang Jing   +2 more
  +4 more sources

Purification of vegetable oils from acrylamide pollutants using metal-organic frameworks

Scientific Reports
Acrylamide is a chemical compound that can form in certain foods during high-temperature cooking processes like frying, roasting, and baking. The presence of acrylamide in used cooking oil has environmental impact; therefore, the purification of used ...
Reda M. Abdelhameed, Randa S. Hasan, Hassan Abdel-Gawad   +2 more
doaj   +1 more source

Synthesis and Antioxidant Activities of Novel Pyrimidine Acrylamides as Inhibitors of Lipoxygenase: Molecular Modeling and In Silico Physicochemical Studies

Molecules
The pyrimidine ring is present in various biomolecules such as DNA and RNA bases, aminoacids, vitamins, etc. Additionally, many clinically used drugs including methotrexate and risperidone contain the pyrimidine heterocyclic scaffold as well.
Michail Saragatsis, Eleni Pontiki
doaj   +1 more source

Living Hydrogels: Harnessing Microorganism–Material Synergy for Next‐Generation Therapeutics

Advanced Science, EarlyView.
 . ABSTRACT Microorganism‐based therapies, particularly those utilizing probiotics, have emerged as a powerful biomedical strategy owing to their inherent living functionalities. These living systems can dynamically interact with host environments and self‐regulate their activity, offering superior adaptability, prolonged functionality, and ...
Shuifang Mao, Bingyao Bai, Xingqian Ye, Yiliang Lin   +3 more
wiley   +1 more source