Results 121 to 130 of about 4,216 (246)

Characterization of the Second-Generation Covalent Fragment Library (CovLib Gen2): Thiol Reactivity Profiling and p53-Y220C Rescue. [PDF]

Drug Des Devel Ther
Schwer M, Aldea SR, Engelhardt MU, Stahlecker J, Rheinganz J, Langkamp A, Boeckler FM.   +6 more
europepmc   +1 more source

Synthesis, Functionalization, and Reactivity of Vinyl Sulfondiimidamides. [PDF]

Angew Chem Int Ed Engl
Rodden KG, Crumpton AE, Dalton SE, Clegg MA, Willis MC.   +4 more
europepmc   +1 more source

Covalent Targeting of Histidine Residues: A Ligand-First Approach. [PDF]

J Med Chem
Alboreggia G, Atienza EL, Muzzarelli K, Assar Z, Pellecchia M.   +4 more
europepmc   +1 more source

Controllable copper-catalysed photo-induced carbonylative cyclization to access dihydroquinolinones and oxindoles. [PDF]

Chem Sci
Zhao YH, Wang LC, Wu XF.
europepmc   +1 more source

Diazo-Preserving Radical Cascades for the Modular Photoinduced Synthesis of Oxindoles and Pyrazolones. [PDF]

Org Lett
Sarró P, Pleixats R, Vallribera A, Gimbert-Suriñach C, Granados A.   +4 more
europepmc   +1 more source

Palladium-catalyzed carbonylative synthesis of acrylamides from alkenyl thianthrenium salts. [PDF]

Chem Sci
A RH, Zhang J, Wu XF.
europepmc   +1 more source

Application of a MALDI mass spectrometry assay to identify covalent fragments targeting the methyl-lysine reader protein MPP8. [PDF]

SLAS Discov
Rubiano JLS, Buttery PH, Gurard-Levin ZA, Norris-Drouin JL, Mather LM, Hardy PB, Frye SV, James LI.   +7 more
europepmc   +1 more source

Toward Chromoselective Transformations in Biological Systems: Perspectives and Challenges

Angewandte Chemie International Edition, EarlyView.
Controlling biological systems with small‐molecule chromophores has evolved into a powerful strategy and is applied from chemical biology to medicine. However, the complexity of in vivo systems cannot be matched by a single wavelength of light. Developing methods to combine and individually control multiple chromophores is crucial.
Nadja A. Simeth
wiley   +1 more source

One-Pot Tandem Approach to Functionalized 3‑Hydroxy-2-furanyl-acrylamides

ACS Omega, 2018
Nagaraju Mupparapu, Shahnawaz Khan, Pankaj Bandhoria, Shunmuganarayanan Athimoolam, Qazi Naveed Ahmed   +4 more
doaj   +1 more source

Visible-Light-Mediated Radical Truce-Smiles Rearrangement via Arylazo Sulfones. [PDF]

JACS Au
Di Terlizzi L, Nicchio L, Montinho-Inacio E, Tiwari N, Derat E, Retailleau P, Fagnoni M, Neuville L, Protti S, Masson G.   +9 more
europepmc   +1 more source