Results 151 to 160 of about 4,216 (246)

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

Chemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda, Alan Pham, SreeNidhi Karnati, Natalia Soto Rodriguez, Alyssa Toner, Wenshe Ray Liu   +5 more
wiley   +1 more source

Development of Efficient Covalent Inactivators of a Fungal Aspartate Semialdehyde Dehydrogenase. [PDF]

Drug Dev Res
Friday SN, Koellner LA, Brown SW, Calbat CN, Curran CF, Dietz JD, Koenig-Dummer A, Friday PD, Parker JA, Simmons NA, Urmey FA, West AN, Zagler SG, Viola RE, Halkides CJ.   +14 more
europepmc   +1 more source

Photolytic Hydrophosphination: Insights Into Catalyzed and Uncatalyzed Processes

Chemistry – A European Journal, EarlyView.
Catalyst‐free photolytic hydrophosphination is demonstrated for vinyl arenes and activated alkenes in polar protic (alcohol) solvents. These reactions appear to be closed‐shell, affirming that even ambient light can impact a reaction—a potentially broad influence on even mundane reactions.
Emma J. Finfer, Evelyn M. Kempf, Rory Waterman   +2 more
wiley   +1 more source

Inverse conjugate additions of acrylic amides and esters with F/Cl/O/N-nucleophiles and CF₃⁺ reagents. [PDF]

Sci Adv
Liu X, Kou Y, Wu H, Liu TX, Liu Q, Zhang Z, Zhang X, Zhang G.   +7 more
europepmc   +1 more source

Synthesis and characterization of amphiphilic nitroxide 1,1,3,3–tetraethylisoindoline–2–oxyl–5–sodium sulfonate (TEIOSNa)

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract The synthesis and characterization of an amphiphilic nitroxide to be used as a controlling agent in a nitroxide‐mediated living radical polymerization in aqueous dispersion media is presented. In the first stage of nitroxide synthesis (phthalimide protection), two reaction methods were employed: traditional and microwave.
Enrique García‐Leal, Martha Eugenia Albores Velasco, René O. Vargas, Rubén Mil‐Martínez   +3 more
wiley   +1 more source

Precipitation-first synthesis and deep profiling of a 1200-member acrylamide library for covalent drug discovery.

Green Chem
Patil P, Ingenito E, Fusco R, Capriello I, Guan Z, Bhalkikar A, Gibbons J, Korba T, Bashkyrtsev S, Tkachenko O, Dömling A.   +10 more
europepmc   +1 more source

Allosteric Covalent Inhibitors of the STAT3 Transcription Factor from Virtual Screening. [PDF]

ACS Med Chem Lett
Szalai TV, di Lorenzo V, Péczka N, Mihalovits LM, Petri L, Ashraf QF, de Araujo ED, Honti V, Bajusz D, Keserű GM.   +9 more
europepmc   +1 more source

Unravelling the initiator‐only stage in alginate grafting: Radical‐induced depolymerization and its impact on acrylamide grafting efficiency

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Free‐radical grafting of natural polymers often assumes that initiators only create active sites before monomer addition. We tested this by exposing sodium alginate to potassium persulphate (KPS) under typical grafting conditions without monomer (acrylamide).
Gustavo P. Zago, João B. P. Soares
wiley   +1 more source

Acrylamide

Environmental Health Perspectives, 1997
openaire   +1 more source

Tunable amylopectin graft copolymers for flocculating and dewatering iron ore tailings

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Polyacrylamide (PAM), the standard flocculant for mining tailings, often produces turbid supernatants and poorly dewatered sediments, limiting water reuse and tailings densification. We synthesized amylopectin‐graft‐poly[(2‐methacryloyloxy)ethyl]trimethylammonium chloride (AP‐g‐PMETAC) copolymers with systematically varied graft frequency (N = 
Gustavo P. Zago, Reinaldo Giudici, João B. P. Soares   +2 more
wiley   +1 more source