Results 41 to 50 of about 4,287,423 (312)
Report of the Roundtable “The Relevance of Hermann Cohen’s Philosophy”
Кантовский сборник, 2022 This report of the roundtable that took place on 25 November 2021 at The Peoples’ Friendship University of Russia (RUDN University) attempts to explain the obvious growth of interest in Neo-Kantian philosophy in general and the philosophy of the head of ...
Vladimir N. Belov
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Navigating the EU AI Act: implications for regulated digital medical products
npj Digital MedicineThe newly adopted EU AI Act represents a pivotal milestone that heralds a new era of AI regulation across industries. With its broad territorial scope and applicability, this comprehensive legislation establishes stringent requirements for AI systems. In
M. Aboy, Timo Minssen, E. Vayena
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
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Antidepressants act by binding to the cholesterol-interaction site at TRKB neurotrophin receptor
bioRxiv, 2019 It is unclear how binding of antidepressant drugs to their targets gives rise to the clinical antidepressant effect. We found that both typical and fast-acting antidepressants bind to a cholesterol interaction motif in the BDNF receptor TRKB, a known ...
P. Casarotto +21 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Cogent Psychology, 2018 How therapists integrate short-term psychodynamic psychotherapy (STPP) and Acceptance and Commitment Therapy (ACT) is not well understood. This study focused on the circumstances used to guide the integration of ACT and STPP as a therapeutic strategy ...
Michelle Matoff
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Acta Iuris Stetinensis, 2018 The paper presents the current state of dogmatic analysis in relation to the issue of the so-called subjective components: act, unlawfulness and circumstances excluding unlawfulness.
Piotr Kardas
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
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Circular RNAs Act as miRNA Sponges.
Advances in Experimental Medicine and Biology, 2018 Majority of RNAs expressed in animal cells lack protein-coding ability. Unlike other cellular RNAs, circular (circ)RNAs include a large family of noncoding (nc)RNAs that lack the 5' or 3' ends. The improvements in high-throughput RNA sequencing and novel
A. Panda
semanticscholar +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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