Results 71 to 80 of about 10,225,052 (294)

Speech Acts [PDF]

open access: yes, 2016
Abstract The essential insight of speech act theory was that when we use language, we perform actions—in a more modern parlance, core language use in interaction is a form of joint action. Over the last thirty years, speech acts have been relatively neglected in linguistic pragmatics, although important work has been done especially in ...
openaire   +3 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Act Utilitarianism [PDF]

open access: yes, 2014
An overview (about 8,000 words) of act utilitarianism, covering the basic idea of the theory, historical examples, how it differs from rule utilitarianism and motive utilitarianism, supporting arguments, and standard objections.
Eggleston, Ben
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

THE ROLE OF NATIONAL PARLIAMENTS IN VERIFYING THE COMPLIANCE WITH THE PRINCIPLES OF PROPORTIONALITY AND SUBSIDIARITY [PDF]

open access: yesChallenges of the Knowledge Society, 2018
The decision-making process of the European Union is a particularly complex one and its democratic legitimacy has almost always been a preoccupation for the citizens involved in European affairs, researchers, practitioners of Union law and, ultimately,
Dragoș – Adrian BANTAȘ
doaj  

On the Institution of Public Hearing – An Analysis from the Theoretical Point of View and the Perspective of the State’s Political Practice (Fifth to Ninth Term of the Sejm of the Republic of Poland) [PDF]

open access: yesKrytyka Prawa
The purpose of the study is to evaluate the public hearings’ role in law-making. The study addresses the problem of whether the institution of public hearing is an instrument that has a real impact on the law-making process.
Bogusław Przywora   +1 more
doaj   +1 more source

Oxygen Hydration Mechanism for the Oxygen Reduction Reaction at Pt and Pd Fuel Cell Catalysts [PDF]

open access: yes, 2011
We report the reaction pathways and barriers for the oxygen reduction reaction (ORR) on platinum, both for gas phase and in solution, based on quantum mechanics calculations (PBE-DFT) on semi-infinite slabs. We find a new mechanism in solution: O_2 → 2O_(
Goddard, William A., III   +4 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Inaction as a Legal Fact in Civil Law (on the Example of the Republic of Belarus)

open access: yesTeisė, 2019
Unlike other legal sciences, the science of civil law did not produce any meaningful theory of inaction as a legal fact. The purpose of this article is to fill in this blank space. As a result of research, the author exposes certain features of the legal
Ana Šafalovič
doaj   +1 more source

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