Results 121 to 130 of about 54,662 (205)

Predictors of in vitro response to somatostatin and dopamine receptor‐targeted treatments are lacking in clinically non‐functioning pituitary tumors

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract Clinically non‐functioning pituitary neuroendocrine tumors (NF‐PitNETs) lack effective medical therapies, and the role of somatostatin receptor ligands (SRLs) and dopamine agonists (DAs) in this setting is controversial. We evaluated the in vitro response of NF‐PitNETs to multiple SRL and/or DA treatments, focusing on the role of receptor ...
Claudia Campana   +9 more
wiley   +1 more source

Prolactinomas in the transition from adolescence to young adulthood: A multicentre, retrospective study from the TALENT group

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract Prolactinomas in the transition age present unique challenges; treatment strategies and long‐term outcomes in this population remain incompletely characterised. This is a multicentre, retrospective study of 110 consecutive patients (33 males) with prolactinomas, aged 15–25 years, across five Italian referral centres (2010–2025).
Dario De Alcubierre   +17 more
wiley   +1 more source

The Skin‐Lightening Efficacy and Mechanisms of Botanical Extracts: A Comprehensive Review

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.
ABSTRACT Background Skin pigmentation is regulated by a complex network involving melanogenesis, melanosome transfer, oxidative stress, environmental stimuli, and epidermal turnover. Botanical extracts and phytochemicals have attracted increasing interest as potential skin‐lightening agents. This review evaluates their efficacy, mechanisms, and safety.
Siting Yang   +6 more
wiley   +1 more source

Case 24: A 42-Year-Old Woman With Fever and Shock. [PDF]

open access: yesJ Korean Med Sci
Bae S, Lee J, Ha J, Lim DJ, Lee J.
europepmc   +1 more source

Liver cirrhosis is associated with altered glucocorticoid metabolism related to disease severity

open access: yesJournal of Internal Medicine, Volume 300, Issue 4, Page 513-527, October 2026.
Abstract Background Liver cirrhosis (LC) is frequently complicated by adrenal dysfunction; however, whether cirrhosis drives the coordinated, pathway‐specific reprogramming of cortisol metabolism remains unclear. Objectives We aimed to characterize axis‐specific alterations in cortisol metabolism in patients with LC, those with adrenal insufficiency ...
Soyeon Park   +8 more
wiley   +1 more source

Short Cationic ACTH-Related Peptides Can Modulate the Na<sub>V</sub>1.8 Channel Functioning, Resulting in an Analgesic Effect. [PDF]

open access: yesInt J Mol Sci
Rogachevskii IV   +13 more
europepmc   +1 more source

Peripheral Inflammation and Sleep Loss Induce Coordinated Motivational Changes: An Experimental Two‐Hit Stress Model

open access: yesJournal of Sleep Research, Volume 35, Issue 5, October 2026.
ABSTRACT Sleep loss and low‐grade inflammation are common stressors that affect behaviour and recovery needs. To examine their separate and combined effects on motivation for everyday behaviours, we developed a two‐hit experimental model. Participants (N = 56, 31 women) completed three experimental visits: sleep saturation (two nights, 9 h in bed/night)
John Axelsson   +6 more
wiley   +1 more source

Postmortem Evidence of CRH Neuron Reduction in Narcolepsy Without Cataplexy With Borderline Hypocretin‐1 Levels

open access: yesJournal of Sleep Research, Volume 35, Issue 5, October 2026.
ABSTRACT Narcolepsy is classified as type 1 (NT1) or type 2 (NT2) mainly according to hypocretin deficiency rather than cataplexy. While CRH neuron loss in the PVN has been described in NT1, it remains unclear whether similar changes occur in narcolepsy without cataplexy.
Ling Shan   +5 more
wiley   +1 more source

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