Results 51 to 60 of about 5,008 (159)

Differences in Clinical Presentation Between Pheochromocytomas and Paragangliomas

Clinical Endocrinology, Volume 103, Issue 5, Page 651-658, November 2025.
ABSTRACT Objectives Pheochromocytomas and sympathetic paragangliomas (PPGLs) are similar in most aspects. However, they differ in genetic etiology, hormonal secretion, and associated neoplasms. This study aimed to investigate differences in clinical presentation between PPGLs. Design This study employs a retrospective cohort design. Patients The cohort
Vincent E. D. Pihlblad, Jan Calissendorff, Henrik Falhammar   +2 more
wiley   +1 more source

HYPERPIGMENTATION AND ACTH – AN OVERVIEW OF LITERATURE [PDF]

Romanian Medical Journal, 2019
Introduction. ACTH (adrenocorticotropic hormone) is a key regulator of adrenal production involving cortisol as an essential hormone for life. The melanin is a pigment which is produced by melanocytes at the level of melanosomes (the melanogenesis ...
Florica Sandru, Mihai Cristian Dumitrascu, Simona Elena Albu, Mara Carsote, Ana Valea   +4 more
doaj   +1 more source

Ectopic ACTH Production Leading to Diagnosis of Underlying Medullary Thyroid Carcinoma

Journal of Investigative Medicine High Impact Case Reports, 2016
Medullary thyroid carcinoma (MTC) has been described as a source of ectopic ACTH secretion in patients with Cushing’s syndrome. This is an infrequent association, occurring in less than 1% of MTC cases. Among these, it is even more unusual for an initial
Leslee N. Matheny MD, Jessica R. Wilson MD, Howard B. A. Baum MD   +2 more
doaj   +1 more source

Olfactory Neuroblastoma Causing Ectopic ACTH Syndrome

Endocrine Journal, 2005
A 39-year-old woman who presented with typical Cushingoid appearance (moon facies, central obesity, purpura) was admitted to our hospital because of pulmonary infection. She was found to have hypertension, severe hypokalemia, and metabolic alkalosis. Endocrine data revealed elevated plasma levels of ACTH and cortisol with lack of circadian rhythm, non ...
Kazuo, Kanno, Yuki, Morokuma, Toru, Tateno, Yuki, Hirono, Kazuhiro, Taki, R Yoshiyuki, Osamura, Yukio, Hirata   +6 more
openaire   +3 more sources

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

Clinical Endocrinology, Volume 103, Issue 4, Page 540-566, October 2025.
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan, James M. Hawley, Leanne Cussen, Ali Abbara, Sophie A. Clarke, Punith Kempegowda, Rima K. Dhillon‐Smith, Puja Thadani, Maureen Busby, Lucy Owusu‐Darkwah, Rachel Marrington, W. Colin Duncan, Robert K. Semple, Richard Quinton, Michael W. O'Reilly   +14 more
wiley   +1 more source

Ectopic ACTH Syndrome in Children and Adolescents [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2011
Ectopic ACTH syndrome (EAS) in youngsters has seldom been reported and is poorly known.We conducted a multicenter retrospective study involving 18 French tertiary hospitals. Cases of EAS presenting Cushing's syndrome before the age of 20 during the period from 1985 to 2008 were analyzed.Ten patients aged 14 to 20 yr were identified and compared to 20 ...
More, Julie, Young, Jacques, Reznik, Yves, Raverot, Gérald, Borson-Chazot, Françoise, Rohmer, Vincent, Baudin, Eric, Coutant, Régis, Tabarin, Antoine, Renseigné, Non   +9 more
openaire   +3 more sources

De Novo GLI2 Missense Variant in a Child With Isolated Hypopituitarism and Craniofacial Anomalies: Expanding the Phenotypic Spectrum

Molecular Genetics &Genomic Medicine, Volume 13, Issue 9, September 2025.
A novel de novo GLI2 variant (p.Arg499Leu) was identified in a child with hypopituitarism and subtle craniofacial and neurodevelopmental features, broadening the clinical spectrum of GLI2‐related disorders and supporting genotype–phenotype correlations.
Himanshu Goel, Katrina Harrison
wiley   +1 more source

Syndrome of ectopic ACTH secretion in a patient without a verified tumor

Ожирение и метаболизм, 2018
Рrevalence of endogenous hypercortisilism is about 5–6 cases per 1 million people. ACTH-dependent hypercortico- sis in the general structure is about 80%.
Ekaterina V. Ershova, Evgeniya S. Senyushkina, Ekaterina A. Troshina   +2 more
doaj   +1 more source

Fragility fractures in well‐differentiated gastroenteropancreatic neuroendocrine tumors: Results from a multicentered retrospective study

Journal of Neuroendocrinology, Volume 37, Issue 9, September 2025.
Abstract Patients with gastroenteropancreatic–neuroendocrine tumors (GEP‐NETs) may present skeletal fragility that might be related to multiple factors, including bone metastases, vitamin D deficiency, hormone secretion, and disease treatments. This study examines the prevalence and determinants of fragility fractures in low grading (G1‐G2) GEP‐NETs ...
Alessandro Brunetti, Miriam Cellini, Elisabetta Lavezzi, Alessandro Zerbi, Giuseppe Ferrillo, Maria Francesca Birtolo, Alfredo Berruti, Guido Cavati, Marta Lagana, Luigi Gennari, Rossano Girometti, Chiara Zuiani, Franco Grimaldi, Andrea G. Lania, Fabio Vescini, Gherardo Mazziotti   +15 more
wiley   +1 more source

Cushing’s syndrome caused by ACTH-producing thymic typical carcinoid with local invasion and regional lymph node metastasis: a case report

Surgical Case Reports, 2018
Background Ectopic ACTH-producing thymic carcinoid tumors are rare, but often behave aggressively with local invasion and distant metastasis. We herein report a case of ACTH-producing thymic typical carcinoid tumor with lymph node metastasis treated by ...
Wakako Fujiwara, Tomohiro Haruki, Yoshiteru Kidokoro, Takashi Ohno, Yohei Yurugi, Ken Miwa, Yuji Taniguchi, Hiroshige Nakamura   +7 more
doaj   +1 more source