Results 61 to 70 of about 9,797 (224)

Asynchronous Rhythm of Steroidogenic Factor 1 and Period Homolog 2 mRNA Expression in Mouse Y1 Adrenocorticol Tumor Cells [PDF]

, 2010
The relationship between the expression of Steroidogenic factor 1 (Sf1) and the circadian-related gene, period homolog 2 (Per2), in the adrenal cortex is still unknown.
Hajime Nawata, Kenji Ohe, Koichi Node, Koichi Oba, Kouichirou Sonoda, Makoto Akashi, Masatoshi Nomura, Ryoichi Takayanagi, Taijiro Okabe, Toshihiko Yanase   +9 more
core   +1 more source

Cushing’s disease [PDF]

, 2012
Cushing’s disease, or pituitary ACTH dependent Cushing’s syndrome, is a rare disease responsible for increased morbidity and mortality. Signs and symptoms of hypercortisolism are usually non specific: obesity, signs of protein wasting, increased blood ...
Bernard Conte-Devolx, Frederic Castinetti, Isabelle Morange, Thierry Brue   +3 more
core   +1 more source

Clinical Implications of Ki‐67 Index, Grade and Hormonal Changes in Pancreatic Neuroendocrine Tumors: Insights Into Tumor Heterogeneity Based on Primary and Secondary Lesions

Journal of Hepato-Biliary-Pancreatic Sciences, Volume 33, Issue 2, Page 141-150, February 2026.
In this retrospective study of metastatic and recurrent pancreatic neuroendocrine tumors, Murakami and colleagues demonstrated frequent discordance in Ki‐67 index and World Health Organization grade between primary and secondary lesions. Increased proliferation did not compromise survival, likely reflecting treatment adaptation. Rare hormonal phenotype
Masatoshi Murakami, Nao Fujimori, Kazuhide Matsumoto, Keijiro Ueda, Kohei Nakata, Masafumi Nakamura, Takeo Yamamoto, Yoshinao Oda, Tetsuhide Ito, Yoshihiro Ogawa   +9 more
wiley   +1 more source

Appendiceal Neuroendocrine Tumor Is a Rare Cause of Ectopic Adrenocorticotropic Hormone Syndrome With Cyclic Hypercortisolism: A Case Report and Literature Review

Frontiers in Endocrinology, 2022
ObjectiveEctopic adrenocorticotropic hormone (ACTH) syndrome (EAS) is a condition of hypercortisolism caused by non-pituitary tumors secreting ACTH. Appendiceal neuroendocrine tumor as a rare cause of ectopic ACTH syndrome was reported scarcely. We aimed
Yu Xing Zhao, Wan Lu Ma, Yan Jiang, Guan Nan Zhang, Lin Jie Wang, Feng Ying Gong, Hui Juan Zhu, Lin Lu   +7 more
doaj   +1 more source

Complications of Cushing's syndrome: state of the art [PDF]

, 2016
Cushing's syndrome is a serious endocrine disease caused by chronic, autonomous, and excessive secretion of cortisol. The syndrome is associated with increased mortality and impaired quality of life because of the occurrence of comorbidities.
Biller, Beverly M. K, Colao, Annamaria, De Martino, Maria Cristina, Isidori, Andrea, Newell Price, John, Pivonello, Rosario   +5 more
core   +1 more source

Emerging methods for subtype differentiation in primary aldosteronism

Journal of Internal Medicine, Volume 299, Issue 2, Page 178-195, February 2026.
Abstract Primary aldosteronism (PA) is a common cause of hypertension. Compared to patients with essential hypertension, untreated PA is associated with a two‐ to fourfold greater risk of cardiovascular disease, renal failure, and death. PA is caused by increased secretion of aldosterone from one adrenal gland in 30% of the patients and both adrenal ...
Oskar Ragnarsson, C. Christofer Juhlin, Tobias Åkerström, Per Dahlqvist, Henrik Falhammar, Per Hellman   +5 more
wiley   +1 more source

Ectopic Cushing Syndrome Due to Colon Cancer With Dual Morphology [PDF]

, 2015
Efst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinnWe report a case of colon cancer, and the most interesting presentation was Cushing’s syndrome (CS).
Bryndis Baldvinsdottir, Helga A Sigurjonsdottir, Jon G Jonasson, Uggi P Agnarsson   +3 more
core   +1 more source

Magnetic resonance imaging features of hypophysitis in patients with cancer treated with immune checkpoint inhibitors

Journal of Neuroendocrinology, Volume 38, Issue 1, January 2026.
This study evaluated pituitary MRI results in cancer patients who experienced immune‐related hypophysitis while receiving immune checkpoint inhibitor treatment. MRI abnormalities were present in 63% of patients at follow‐up and 56% of patients at diagnosis, mostly in patients with multiple hormonal deficiencies.
Anna Angelousi, Stavroula Asimakopoulou, Charis Bourgioti, Amalia Anastasopoulou, Spyridon Kazanas, Panagiotis Diamantopoulos, Athina Karabela, Elisavet Tasouli, Lia‐Angela Moulopoulos, Dimitrios C. Ziogas, Helen Gogas   +10 more
wiley   +1 more source

Ectopic adrenocorticotropic hormone syndrome presenting as hypokalemic metabolic alkalosis and hypertension

The Journal of Association of Chest Physicians, 2016
The ectopic adrenocorticotropic hormone (ACTH) syndrome is an uncommon cause of hypercortisolism, which should be considered in patients with hypokalemic metabolic alkalosis and hypertension in the context of lung neoplasm.
Mansoor C Abdulla, Jemshad Alungal
doaj   +1 more source

Microprolactinoma (Pituitary Adenoma) as a Cause of Secondary Headache in a Pediatric Patient With Pain and Restricted Mouth Opening: A Case Report

Case Reports in Dentistry, Volume 2026, Issue 1, 2026.
Introduction The aim of this paper is to report a case of a patient coming to the attention of the general dentist for TMD pain, limited mouth opening, and headache, for which the prescription of a blood test and an magnetic resonance imaging (MRI) led to the incidental diagnosis of a microadenoma of the pituitary gland. Case Presentation A 15‐year‐old
Raluca Draghici, Ovidiu Ionut Saracutu, Matteo Pollis, Daniele Manfredini, Vlaho Brailo   +4 more
wiley   +1 more source