Results 121 to 130 of about 860,471 (297)

Immature defense mechanisms and suicide attempts in borderline personality organization: a clinical sample study

open access: yesFrontiers in Psychology
ObjectiveThis study aimed to investigate the relationship between defense mechanisms and suicide attempts in individuals with borderline personality organization (BPO), considering the high prevalence of suicide attempts in this population.MethodsA total
Ardil Bayram Şahin   +4 more
doaj   +1 more source

Autobiographical Fiction: Intimate Encounters with Louise Bourgeois and Melanie Klein Inside the Freud Museum [PDF]

open access: yes, 2016
An analysis of Louise Bourgeois' exhibition at the Freud Museum London in relation to Melanie Klein's ideas of acting ...
Morra, Joanne
core  

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Acting Out: a preliminary exploration of the ethical implications of using ancient Greek Tragedy as a means of Psychotherapy

open access: yesMediterranean Journal of Clinical Psychology
This paper aims to explore the ethical issues which arise with the employment of the performance or viewing of drama as a therapeutic process for ‘mental illness’.
Patrick Guy Browne Johnson
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Pure spinor indications of ultraviolet finiteness in D=4 maximal supergravity

open access: yes, 2015
The ultraviolet divergences of amplitude diagrams in maximal supergravity are characterised by a first possible divergence at seven loops for the 4-point amplitude (logarithmic) and, in its absence, at eight loops.
Karlsson, Anna
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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