Results 151 to 160 of about 7,838,390 (295)

When acting becomes abuse: problems with playing the ‘part’ of the actor

open access: yes, 2018
In January 2018, New Zealand actor Rene Naufahu, best known for his role on a long-running soap opera, was sentenced for a series of indecent assaults on young women during his one-on-one acting classes.
Willis, Emma
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

[Acting out a bull fight]

open access: yes, 1950
Photograph of two dancers from the modern dance group acting out a bullfighting scene. The dancer on the left has a costume head of a bull that is grey-colored with light-colored horns. The dancer has their right leg lifted into the air behind them while

core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Moving beyond a fictional character: changes in contemporary acting

open access: yes, 2014
Acting by its usual and simplest definition is the art or practice of representing a fictional character on a stage by means of movement, gesture, and intonation. However contemporary theatre practice encourages the reconsideration of such definition and
Mažeikienė, Rūta
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Long-acting preparations of exenatide

open access: yes, 2013
Yunpeng Cai,1,2,* Liangming Wei,3,* Liuqing Ma,2 Xiwen Huang,2 Anqi Tao,2 Zhenguo Liu,1 Weien Yuan1,2 1Department of Neurology, Xinhua Hospital affiliated to Shanghai Jiaotong University School of Medicine, 2School of Pharmacy, Shanghai JiaoTong ...
Liu Z   +6 more
core  

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