Results 11 to 20 of about 18,082 (276)

Actinic keratosis metrics. [PDF]

Arch Dermatol Res
AbstractActinic keratosis (AK) is a common precancerous skin condition predominantly affecting older males with fair skin and significant UV exposure. The clinical significance of AK is related to its potential for malignant transformation and progression to squamous cell carcinoma (SCC).
Burstein SE, Maibach H.
europepmc   +5 more sources

The Genomic Landscape of Actinic Keratosis [PDF]

Journal of Investigative Dermatology, 2021
Actinic keratoses (AKs) are lesions of epidermal keratinocyte dysplasia and are precursors for invasive cutaneous squamous cell carcinoma (cSCC). Identifying the specific genomic alterations driving the progression from normal skin to skin with AK to skin with invasive cSCC is challenging because of the massive UVR-induced mutational burden ...
Jun Wang, Abha Gulati, Ai Nagano, Chinedu Anthony Anene, Findlay Bewicke-Copley, Catherine A. Harwood, Catherine A. Harwood, Karin J. Purdie, Gareth J. Inman, Charlotte M. Proby, Irene M. Leigh, Jason Thomson   +11 more
openaire   +4 more sources

Virtual consultation for actinic keratosis [PDF]

BJGP Open, 2020
Actinic keratoses (AK) are keratotic lesions presenting on chronically ultraviolet-exposed skin. The rate of malignant progression of a single AK to squamous cell carcinoma (SCC) remains uncertain, with reports ranging from 0.025%–20%.1,2 Patients receiving long-term immunosuppressive medications are at higher risk of developing AK.3 The estimated ...
Chamandeep Thind, Sukhjit Dhariwal, Simon Tso, Bruce C Gee, Tushar Hari, Alison Bedlow, Kamal Kaur   +6 more
openaire   +4 more sources

Explainable human‐in‐the‐loop healthcare image information quality assessment and selection

CAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract Smart healthcare applications cannot be separated from healthcare data analysis and the interactive interpretability between data and model. A human‐in‐the‐loop active learning approach is introduced to reduce the cost of healthcare data labelling by evaluating the information quality of unlabelled medical data and then screening the high ...
Yang Li, Sezai Ercisli
wiley   +1 more source

Actinic keratosis (review of literature)

Biomedical Photonics, 2022
Actinic keratosis is an important medical and social problem, the correct diagnosis and treatment of which will help to avoid the development of invasive forms of cutaneous squamous cell carcinoma.
E. V. Filonenko, S. S. Okushko
doaj   +1 more source

Capecitabine-induced activation of actinic keratosis: A common but underrecognized adverse event

Current Problems in Cancer: Case Reports, 2021
We report a case of a 70-year-old woman undergoing chemotherapy with capecitabine for breast cancer who presented with a diffuse erythematous facial eruption, consistent with actinic keratosis activation.
Samantha Marley, Shelly Stepenaskie, Naiara S. Barbosa   +2 more
doaj   +1 more source

Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy [PDF]

, 2017
BACKGROUND. Actinic keratosis is a precursor to cutaneous squamous cell carcinoma. Long treatment durations and severe side effects have limited the efficacy of current actinic keratosis treatments.
Ahu Turkoz, Andras Schaffer, Arturo P. Saavedra, Cipolat, Fenske, Hengameh Mirzaalian, Jean-Pierre Eliane, Lynn A. Cornelius, Mary Tabacchi, Michael Wallendorf, Raphael Kopan, Salasche, Sara Moradi Tuchayi, Seckin, Shadmehr Demehri, Sindhu Manivasagam, Stockfleth, Trevor J. Cunningham, Warino   +18 more
core   +2 more sources

Retinoids for prevention and treatment of actinic keratosis [PDF]

Anais Brasileiros de Dermatologia, 2013
Actinic keratosis is a common cause of dermatological consultations and it presents a strong association with squamous cell carcinoma. Many substances are used for treatment and prevention, such as retinoids.
Mayra Ianhez, Luiz Fernando Fróes Fleury Junior, Hélio Amante Miot, Edileia Bagatin   +3 more
doaj   +1 more source

Actinic keratoses show variable histological basal growth patterns - a proposed classification adjustment [PDF]

, 2017
Background: Common histological classification schemes of actinic keratoses (AK) do not evaluate growth patterns at basal epidermal aspects of AK. Until now, the importance of basal epidermal growth patterns of AK has not been studied. Objective: To
Dirschka, T., Gambichler, T., Gupta, G., Schmitz, L., Stockfleth, E., Stücker, M., Szeimies, R.M.   +6 more
core   +1 more source

Accuracy of mobile digital teledermoscopy for skin self-examinations in adults at high risk of skin cancer: an open-label, randomised controlled trial [PDF]

, 2020
Background: Skin self-examinations supplemented with mobile teledermoscopy might improve early detection of skin cancers compared with naked-eye skin self-examinations.
Avilés-Izquierdo, Baade, Berwick, Boyce, Chambers, Chao, Djaja, Genders, Hamidi, Janda, Janda, Janda, Kandel, King, Kroemer, Li, Luttrell, Manahan, Markun, Morze, Pike, Rat, Robinson, Tschandl, Venables, Wu   +25 more
core   +1 more source