Results 51 to 60 of about 18,082 (276)

Multifunctional liposomes remodeling tumor microenvironment for enhancing Hemoporfin‐mediated photodynamic therapy

open access: yesBMEMat, EarlyView.
BSO/CAT@Liposomes‐Hemoporfin nanoparticles could significantly enhance the ROS levels in cells in vitro and tumor model in vivo, which is attributed to the increasement of Hemoporfin in the tumor, depletion of GSH, and enhancement of local oxygen concentration.
Yawen Chen   +7 more
wiley   +1 more source

Whole-exome sequencing validates a preclinical mouse model for the prevention and treatment of cutaneous squamous cell carcinoma [PDF]

open access: yes, 2017
Cutaneous squamous cell carcinomas (cSCC) are among the most common and highly mutated human malignancies. Solar UV radiation is the major factor in the etiology of cSCC. Wholeexome sequencing of 18 microdissected tumor samples (cases) derived from SKH-1
Aikseng Ooi   +16 more
core   +2 more sources

Cold atmospheric plasma combined with nanoparticles in cancer therapy

open access: yesInterdisciplinary Medicine, EarlyView.
Cold atmospheric plasma (CAP) generates a range of reactive oxygen and nitrogen species (RONS), including singlet oxygen (1O2), hydrogen peroxide (H2O2), hydroxyl radicals (·OH), nitrate (NO3− ${{\text{NO}}_{3}}^{-}$), and nitrite (NO2− ${{\text{NO}}_{2}}^{-}$), which induce oxidative stress and apoptosis in cancer cells.
Yunhao Wang   +7 more
wiley   +1 more source

CURRENT VIEWS ON THE PATHOGENESIS AND EARLY DIAGNOSIS OF ACTINIC KERATOSIS

open access: yesПаёми Сино, 2023
The article provides an overview of the epidemiology and pathogenesis of actinic keratosis (AK) and its clinical differentiation from cutaneous squamous cell carcinoma (SCC).
A.A. SYDIKOV, G.B. PYAGAY, O.G. PYAGAY
doaj   +1 more source

Significant Role of Collagen XVII And Integrin beta 4 in Migration and Invasion of The Less Aggressive Squamous Cell Carcinoma Cells [PDF]

open access: yes, 2017
Collagen XVII and integrin alpha 6 beta 4 have well-established roles as epithelial adhesion molecules. Their binding partner laminin 332 as well as integrin alpha 6 beta 4 are largely recognized to promote invasion and metastasis in various cancers, and
Franzke, Claus-Werner   +13 more
core   +2 more sources

Comparative histochemical study of Bowen’s disease and actinic keratosis: preserved normal basal cells in Bowen’s disease

open access: yesEuropean Journal of Histochemistry, 2009
The degree of DNA-instability as revealed by immunohistochemical staining with anti-cytidine antibody after acid hydrolysis (DNA-instability test) has been recently used as a marker of malignancy.
H Ishida   +8 more
doaj   +1 more source

Measuring daylight:a review of dosimetry in daylight photodynamic therapy [PDF]

open access: yes, 2019
Successful daylight photodynamic therapy (DPDT) relies on the interaction of light, photosensitisers and oxygen. Therefore, the ‘dose’ of light that a patient receives during treatment is a clinically relevant quantity, with a minimum dose ...
Eadie, Ewan   +3 more
core   +2 more sources

Immunological and Viral Profiles of Squamous Cell Carcinoma in Transplant and Non‐Transplant Patients in Singapore

open access: yesJEADV Clinical Practice, EarlyView.
Cutaneous squamous cell carcinoma (cSCC) exhibits a pro‐tumorigenic immune environment, increased oncologic signalling, and tumour remodelling, with three immune subgroups from ‘cold’ to ‘hot’. Organ transplant recipients (OTR) with cSCC showed reduced T‐cells and greater viral enrichment, especially HPV, and a higher disease burden.
Choon Chiat Oh   +8 more
wiley   +1 more source

Systemic toxicity to betamethasone ointment

open access: yesClinical Case Reports, 2020
Topically applied betamethasone for actinic keratosis may trigger systemic side effects. Systemic side effects of topical betamethasone may completely resolve after discontinuation of the causative agent.
Rahim Aliyev, Josef Finsterer
doaj   +1 more source

Current evidence and applications of photodynamic therapy in dermatology [PDF]

open access: yes, 2014
In photodynamic therapy (PDT) a photosensitizer – a molecule that is activated by light – is administered and exposed to a light source. This leads both to destruction of cells targeted by the particular type of photosensitizer, and immunomodulation ...
Lin, Jennifer Y, Wan, Marilyn T
core   +2 more sources

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