Results 51 to 60 of about 9,440 (219)

Improving imiquimod use in cervical high‐grade squamous intraepithelial lesions: A qualitative study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Adequate patient counselling on imiquimod treatment, including the possible application methods and potential side effects, along with optimal guidance during treatment, contributes to a better patient experience and reduces the likelihood of early discontinuation of treatment.
Caroline L. P. Muntinga, Helena C. J. Schellekens, Charlotte G. J. Penders, Hélène van Meir, Gatske M. Nieuwenhuyzen‐De Boer, Anna J. M. van de Sande, Heleen J. van Beekhuizen, Peggy J. de Vos Van Steenwijk, Ruud L. M. Bekkers, Edith M. G. van Esch   +9 more
wiley   +1 more source

Cardiovascular Drug Use and Risk of Actinic Keratosis: A Case-Control Study

Dermatology and Therapy, 2020
Introduction Actinic keratosis (AK) is a precancerous skin lesion. Currently, many experts treat actinic keratosis as squamous cell carcinoma in situ. It is well established that exposure of the skin to ultraviolet radiation is a major risk factor for ...
Olga Warszawik-Hendzel, Małgorzata Olszewska, Adriana Rakowska, Mariusz Sikora, Piotr Hendzel, Lidia Rudnicka   +5 more
doaj   +1 more source

Cetuximab plus 5‐fluorouracil in patients with advanced cutaneous squamous cell carcinoma: a retrospective cohort study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background For patients with locally advanced (la) or metastatic (m) cutaneous squamous cell carcinoma (cSCC) who are not candidates for curative surgery/radiation or systemic anti‐PD1 therapy, anti‐EGFR in combination with chemotherapy is a rational treatment option.
Julia Huynh, Thomas Eigentler, Rose K. C. Moritz, Gabriela Poch, Max Schlaak, Gabor Dobos   +5 more
wiley   +1 more source

To PDT or Not to PDT, That Is the Question—A Retrospective Analysis of Carbon Emissions Associated With Travel for Photodynamic Therapy

JEADV Clinical Practice, EarlyView.
Nicola Kearney, Ibrahim Afridi, Mary Laing   +2 more
wiley   +1 more source

Simulated daylight vs. conventional PDT for clinical superficial BCC: A randomized controlled trial

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In this single‐centre, non‐inferiority, randomized controlled trial, SDL‐PDT (n = 95 lesions) was less effective than C‐PDT (n = 98 lesions) in treating superficial basal cell carcinoma One‐year clearance rates: 61.3% with SDL‐PDT versus 91.8% with C‐PDT (p < 0.001).
Alexandra Sjöholm, Eva Backman, Maja Modin, Julia Fougelberg, Magdalena Claeson, John Paoli   +5 more
wiley   +1 more source

Actinic keratosis on the rise in Australia [PDF]

F1000Research, 2014
Objectives:To report the burden and cost of actinic keratosis (AK) treatment in Australia and to forecast the number of AK treatments and the associated costs to 2020.Design and setting:A retrospective study of data obtained from medicare Australia for AK treated by cryotherapy between 1 January 1994 and 31 December 2012, by year and by state or ...
Eshini Perera, Sean McGuigan, Rodney Sinclair   +2 more
openaire   +3 more sources

An Unusual Case of Perineural Infiltration and Orbital Invasion of Squamous Cell Carcinoma Associated with Actinic Keratosis

Case Reports in Ophthalmological Medicine, 2020
Actinic keratosis is considered a precancerous lesion, constituting a precursor to squamous cell carcinoma (SCC) formation. Perineural invasion has been observed in patients with cutaneous carcinoma due to local subcutaneous tissue destruction and ...
Edgard Farah, Marie Callet, Augustin Leclerc, Tryfon Rotsos, Chrysanthos Symeonidis, Pierre-Vincent Jacomet, Olivier Galatoire   +6 more
doaj   +1 more source

Accuracy of Cytological Methods in Early Detection of Oral Squamous Cell Carcinoma and Potentially Malignant Disorders: A Systematic Review and Meta‐Analysis

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Introduction Oral squamous cell carcinoma (OSCC) carries significant global mortality rates. Brush cytology presents a potential adjunctive tool for early detection and monitoring of OSCC and oral potentially malignant disorders (OPMDs). This study aims to systematically evaluate the diagnostic accuracy of cytology for detecting OSCC and OPMDs
Hoda Tayebi‐Hillali, Alejandro I. Lorenzo‐Pouso, Xabier Marichalar‐Mendía, Pilar Gándara‐Vila, Dolores Reboiras‐López, Andrés Blanco‐Carrión, Martina Coppini, Vito Carlo Alberto Caponio, Mario Pérez‐Sayáns   +8 more
wiley   +1 more source

Identification of differentially expressed genes in actinic keratosis samples treated with ingenol mebutate gel.

PLoS ONE, 2020
Actinic keratosis is a common skin disease that may progress to invasive squamous cell carcinoma if left untreated. Ingenol mebutate has demonstrated efficacy in field treatment of actinic keratosis.
Sonia Segura, Alejandra Gadea, Lara Nonell, Evelyn Andrades, Silvia Sánchez, Ramon Pujol, Inmaculada Hernández-Muñoz, Agustí Toll   +7 more
doaj   +1 more source

Identification of BAHD‐acyltransferase enzymes involved in ingenane diterpenoid biosynthesis

New Phytologist, EarlyView.
Summary The plant family Euphorbiaceae is an abundant source of structurally complex diterpenoids, many of which have reported anticancer, anti‐HIV, and anti‐inflammatory activities. Among these, ingenol‐3‐angelate (1a; tradename: Picato®), isolated from Euphorbia peplus, has potent antitumor activity.
Carsten Schotte, Matilde Florean, Tomasz Czechowski, Alison Gilday, Ryan M. Alam, Kerstin Ploss, Jens Wurlitzer, Yi Li, Prashant Sonawane, Ian A. Graham, Sarah E. O'Connor   +10 more
wiley   +1 more source