Results 11 to 20 of about 355 (117)

Diagnostics to support mycetoma management-Development of two target product profiles. [PDF]

Trop Med Int Health, 2022
Abstract Objective Mycetoma is a neglected tropical disease caused by more than 70 different microorganisms and identified by the WHO as one of the high‐priority diseases for developing diagnostic tests. To ensure the production of diagnostic assays for use by clinical staff in endemic regions, target product profiles (TPPs) were designed.
Fongwen N, Asiedu KB, Bakhiet S, Bakhiet S, Bonifaz A, Cruz I, Argaw D, Estrada-Chavez G, Fahal AH, Litvintseva A, Marks M, Salinas-Carmona MC, Sow D, van de Sande WWJ.   +13 more
europepmc   +2 more sources

Nonmycetomic Actinomadura madurae infection in a patient with AIDS. [PDF]

J Clin Microbiol, 1992
Actinomadura madurae is an aerobic actinomycete which is best known worldwide as the cause of actinomycotic mycetomas. It has not previously been reported to have caused invasive pulmonary or disseminated infection in humans. We describe an AIDS patient with opportunistic A. madurae-induced pneumonia and bacteremia. The isolate from the patient's blood
McNeil MM, Brown JM, Scalise G, Piersimoni C.   +3 more
europepmc   +4 more sources

Molecular diagnosis of Actinomadura madurae infection by 16S rRNA deep sequencing. [PDF]

J Clin Microbiol, 2013
ABSTRACT Next-generation DNA sequencing can be used to catalog individual organisms within complex, polymicrobial specimens. Here, we utilized deep sequencing of 16S rRNA to implicate Actinomadura madurae as the cause of mycetoma in a diabetic patient when culture and conventional molecular methods were ...
Salipante SJ, Sengupta DJ, Hoogestraat DR, Cummings LA, Bryant BH, Natividad C, Thielges S, Monsaas PW, Chau M, Barbee LA, Rosenthal C, Cookson BT, Hoffman NG.   +12 more
europepmc   +4 more sources

The Accuracy of Histopathological and Cytopathological Techniques in the Identification of the Mycetoma Causative Agents. [PDF]

PLoS Neglected Tropical Diseases, 2019
Mycetoma is a devastating neglected tropical disease, caused by various fungal and bacterial pathogens. Correct diagnosis to the species level is mandatory for proper treatment.
Emmanuel Edwar Siddig, Najwa Adam Mhmoud, Sahar Mubarak Bakhiet, Omnia Babekir Abdallah, Salwa Osman Mekki, Nadia I El Dawi, Wendy Van de Sande, Ahmed Hassan Fahal   +7 more
doaj   +2 more sources

Global sociodemographic, clinical, and epidemiological profiling of patients with mycetoma: A systematic review. [PDF]

PLoS Neglected Tropical Diseases
BackgroundMycetoma is a neglected tropical disease that affects subcutaneous tissues. This chronic granulomatous inflammatory disease often leads to high morbidity rates, including amputation, disability and social stigma. Despite its substantial impact,
Mohamed Elmuntasir Salah, Michelle L Fearon Scales, Kirlus Habib, Fadila Alhamwi, Suad Abdelwahab, Yassin Ahmed, Manal Mohamed Khalid, Dallas J Smith, Ahmed Fahal   +8 more
doaj   +2 more sources

Characterization of the Maduropeptin Biosynthetic Gene Cluster from Actinomadura madurae ATCC 39144 Supporting a Unifying Paradigm for Enediyne Biosynthesis [PDF]

Journal of the American Chemical Society, 2007
Wen Liu, Tae-Jin Oh, Ben Shen
exaly   +2 more sources

Wako β‐D‐glucan assay can be used to measure serum β‐D‐glucan in Sudanese patients to aid with diagnosis of eumycetoma caused by Madurella mycetomatis

Journal of the European Academy of Dermatology and Venereology, Volume 37, Issue 4, Page 783-786, April 2023., 2023
Abstract Background Eumycetoma is a neglected tropical infection of the subcutaneous tissue commonly caused by the fungus Madurella mycetomatis. Previously, we demonstrated that β‐D‐glucan was present in the serum of eumycetoma patients. Objective To compare the performance of the recently approved easy‐to‐use Wako β‐D‐glucan assay to that of the ...
Bertrand Nyuykonge, Emmanuel Siddig, Najwa A. Mhmoud, Sahar Bakhiet, Eduard Zijlstra, Annelies Verbon, Ahmed H. Fahal, Wendy W. J. van de Sande   +7 more
wiley   +1 more source

Ultrasound‐guided fine‐needle aspiration cytology significantly improved mycetoma diagnosis

Journal of the European Academy of Dermatology and Venereology, Volume 36, Issue 10, Page 1845-1850, October 2022., 2022
Abstract Background Ultrasound (US)‐guided fine‐needle aspiration cytology (US‐FNAC) has improved the diagnosis of many malignancies, infections and other diseases as it is safe, simple, quick and accurate. In mycetoma, it is assumed that this technique may have a better diagnostic yield than the conventional FNAC as it can accurately identify the ...
E.E. Siddig, O. El Had Bakhait, M. El nour Hussein Bahar, E. Siddig Ahmed, S.M. Bakhiet, M. Motasim Ali, O. Babekir Abdallah, R. Ahmed Hassan, A. Verbon, W.W.J. van de Sande, A.H. Fahal   +10 more
wiley   +1 more source

Susceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil [PDF]

Archives of Biological Sciences, 2008
In vitro susceptibility of the turpentine oil obtained from Pinus pinaster oleoresin was evaluated against three Sudanese clinical isolates of Actinomadura madurae, which is the main causative agent of actinomycetoma.
Stojković D., Soković Marina, Glamočlija Jasmina, Džamić Ana, Ristić M., Fahal A., Khalid Sami, Đuić Ivana, Petrović Silvana   +8 more
doaj   +1 more source

Cystic form of Actinomycotic mycetoma: A new case with a diagnostic challenge

Clinical Case Reports, Volume 9, Issue 4, Page 2449-2452, April 2021., 2021
Mycetoma, commonly known as Madura foot, is a chronic granulomatous infection caused either by fungi (eumycetoma) known as actinomycete. This disease occurs preferentially in young adults, and it affects the foot in particular. We report a Tunisian case of mycetoma occurring in an old patient, particular by its cystic presentation.
Ahlem Bellalah, Nouha Ben Abdeljelil, Manel Njima, Seifeddine Ben Hammouda, Sarah Ben Khalifa, Mustapha Koubaa, Abdelfatteh Zakhama, Rim Hadhri   +7 more
wiley   +1 more source