Distinct Microbiota and Functional Pathway Profiles Define Success and Failure in Regenerative Endodontic Treatment. [PDF]
ABSTRACT Aim To characterize the intracanal microbiota and identify key microbial taxa and functional pathways associated with regenerative endodontic treatment (RET) outcomes. Methodology In this observational cohort study, 196 samples were collected at five time points from external tooth surfaces (T1, T4) and root canals (T2, T3, T5).
Naorem LD +7 more
europepmc +2 more sources
Case Report: Fournier's gangrene caused by Gleimia hominis [PDF]
BackgroundFournier's gangrene is typically polymicrobial necrotizing fasciitis of the perineal/genital regions. Gleimia hominis (Actinomycetaceae) is a rare anaerobic Gram-positive rod whose clinical role remains poorly defined.Case presentationA 71-year-
Jin Woong Suh +2 more
doaj +2 more sources
Indicator bacteria taxa reveal breeding site origins of Aedes aegypti mosquitoes [PDF]
Background The microbiota of adult mosquitoes reflects both their life history and the environments they encounter. Linking specific bacterial communities in adult mosquitoes to their larval aquatic habitats would suggest that microbiota profiling can ...
Katherine D. Mosquera, Olle Terenius
doaj +2 more sources
Integrated analysis reveals microbiota–metabolite–immune alterations associated with coronary heart disease [PDF]
BackgroundThe relationship between gut microbiota, metabolites, immune environment, and coronary heart disease (CHD) remains incompletely understood.MethodsThis study enrolled 100 non-CHD controls and 302 CHD patients, including 102 with acute coronary ...
Baoquan Ren +6 more
doaj +2 more sources
Thoracic Actinomycosis: A Rare Cause of Pleural Thickening. [PDF]
We report a case of a man who presented with a chest wall mass and was found to have pleural thickening on PET, with features concerning for mesothelioma. Further investigation revealed a diagnosis of actinomyces, a rare infectious cause of pleural thickening.
Shum E +5 more
europepmc +2 more sources
Specific alterations in the gut microbiome and metabolome across disease locations of Crohn’s disease: a systematic review [PDF]
Background Crohn’s disease (CD) exhibits substantial heterogeneity in disease behavior and therapeutic outcomes across distinct disease locations. Specific alterations in the gut microbiota and metabolites may drive this variation.
Jieqing Huang +4 more
doaj +2 more sources
The Role of the Gut Microbiota in Allogeneic Hematopoietic Cell Transplantation. [PDF]
ABSTRACT Allogeneic hematopoietic cell transplantation (allo‐HCT) is an effective treatment for patients with high‐risk hematologic malignancies. Over the last decade, gut microbiota composition during allo‐HCT has been associated with patients' outcomes.
Hao W +4 more
europepmc +2 more sources
Application of PathoChip to urine-derived nucleic acids for broad microbial profiling in men with suspected prostate cancer: setup of a methodological workflow and pilot feasibility study [PDF]
Background: Urine-based liquid biopsy is an attractive non-invasive source of prostate cancer (PCa) biomarkers, but urinary microbiome studies have mainly relied on 16S rRNA sequencing or shotgun metagenomics.
Maurizia Mello-Grand +10 more
doaj +2 more sources
Genital Lichen Sclerosus—The Role of the Vulvar Microbiome [PDF]
Background and Objectives: Lichen sclerosus (LSc) is a chronic inflammatory and sclerosing condition that primarily affects the genital region. In women, vulvar lichen sclerosus presents with a wide range of clinical features, including pruritus ...
Sandra Jerkovic Gulin +6 more
doaj +2 more sources
Multi-omics characterization of new and aged Daqu reveals region-specific microbial succession and metabolic signatures in Maotai-flavor liquor fermentation [PDF]
Daqu is an essential fermentation starter that drives the formation of the characteristic flavor of Maotai-flavor liquor, yet the ecological and metabolic mechanisms underlying its regional differentiation and maturation remain poorly resolved.
Kejia Wang +6 more
doaj +2 more sources

