Results 71 to 80 of about 2,800 (185)

Unveiling the Relationship Between Oral Microbiota and Alzheimer's Disease: A Genetic Instrumental Variable Analysis via Mendelian Randomization

Brain and Behavior, Volume 15, Issue 8, August 2025.
This study investigated the association between oral microbiota (OM) and Alzheimer's disease (AD). The causal relationship between OM and AD was established using Mendelian randomization (MR) methods and further supported by gene function analyses. ABSTRACT Background: The potential relationship between oral microbiota (OM) and Alzheimer's disease (AD)
Zhichao Li, Yihan Kang, Shuai Li, Shiqi Guo, Hui Zheng   +4 more
wiley   +1 more source

Altered gut microbiota and short chain fatty acids in Chinese children with autism spectrum disorder

Scientific Reports, 2019
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is characterized by impairments in social interactions and communication, restricted interests and repetitive behaviors. Several studies report a high prevalence of gastrointestinal (GI)
Simeng Liu, Enyao Li, Zhenyu Sun, Dongjun Fu, Guiqin Duan, Miaomiao Jiang, Yong Yu, Lu Mei, Pingchang Yang, Youcai Tang, Pengyuan Zheng   +10 more
doaj   +1 more source

Sputum Microbiota Compositions Correlate With Metabolome and Clinical Outcomes of COPD‐Bronchiectasis Association: A Prospective Cohort Study

Exploration, Volume 5, Issue 4, August 2025.
This study aimed to determine how microbiota compositions (via 16S rRNA sequencing) correlate with clinical outcome and metabolome (via liquid chromatography/mass spectrometry) of CBA. Sputum microbiome and metabolome profiles of CBA were well separated from COPD but not bronchiectasis, partly driven by the higher abundance of Proteobacteria in CBA ...
Zhen‐feng He, Xiao‐xian Zhang, Cui‐xia Pan, Xin‐zhu Yi, Yan Huang, Chun‐lan Chen, Shan‐shan Zha, Lai‐jian Cen, Han‐qin Cai, Lei Yang, Jia‐qi Gao, Hui‐min Li, Zhen‐hong Lin, Sheng‐zhu Lin, Zhang Wang, Nan‐shan Zhong, Wei‐jie Guan   +16 more
wiley   +1 more source

High throughput DNA sequencing to detect differences in the subgingival plaque microbiome in elderly subjects with and without dementia [PDF]

, 2012
BACKGROUND: To investigate the potential association between oral health and cognitive function, a pilot study was conducted to evaluate high throughput DNA sequencing of the V3 region of the 16S ribosomal RNA gene for determining the relative abundance ...
Andrew F Cockburn, Bei Wu, Brenda L Plassman, Christopher F Cuff, Donald Primerano, Goran Boskovic, James Denvir, Jonathan M Dehlin, Richard Crout, Tiffany Ngan   +9 more
core   +1 more source

Bridging lab and industry: The impact of a bio‐conversion unit on black soldier fly larvae production and microbiome dynamics

JSFA reports, Volume 5, Issue 7, Page 304-314, July 2025.
Abstract Background This study evaluates the viability of a novel bio‐conversion unit (BCU) for extensive black soldier fly larvae (BSFL) production as a sustainable feed additive for livestock. The BCU's effectiveness in converting organic byproducts into valuable biomass via the production of BSFL was assessed to reduce reliance on environmentally ...
William J. S. Edwards, Chloe Skingle, Richard Small, Robert Barker, Anastasios D. Tsaousis   +4 more
wiley   +1 more source

A genome-wide association study reveals the relationship between human genetic variation and the nasal microbiome

Communications Biology
The nasal cavity harbors diverse microbiota that contributes to human health and respiratory diseases. However, whether and to what extent the host genome shapes the nasal microbiome remains largely unknown. Here, by dissecting the human genome and nasal
Xiaomin Liu, Xin Tong, Leying Zou, Yanmei Ju, Mingliang Liu, Mo Han, Haorong Lu, Huanming Yang, Jian Wang, Yang Zong, Weibin Liu, Xun Xu, Xin Jin, Liang Xiao, Huijue Jia, Ruijin Guo, Tao Zhang   +16 more
doaj   +1 more source

The human urinary microbiome; bacterial DNA in voided urine of asymptomatic adults [PDF]

, 2013
The urinary microbiome of healthy individuals and the way it alters with ageing have not been characterised and may influence disease processes. Conventional microbiological methods have limited scope to capture the full spectrum of urinary bacterial ...
Brown, Richard, Drake, Marcus J., Jacobson, S. K, Jacobson, S. Kim, Lewis, Debbie A., Lewis, Deborah, Marchesi, Julian R., White, Paul, Williams, Jon   +8 more
core   +4 more sources

Exploring the Gut and Oral Microbiomes in Psychoactive Substance Use: A Scoping Review of Clinical Studies

Journal of Neurochemistry, Volume 169, Issue 7, July 2025.
Substance use disorders are linked to high treatment dropout rates and limited therapeutic options. Clinical studies show that substance use disrupts gut and oral microbiomes, decreasing beneficial bacteria and increasing proinflammatory and opportunistic microbes.
Artūras Barkus, Vaida Baltrūnienė, Lina Barkienė, Justė Baušienė, Tomas Baltrūnas, Marius Brazys, Kornelija Rauduvytė, Paulina Kazlauskaitė, Augustinas Baušys   +8 more
wiley   +1 more source

Daily HIV pre-exposure prophylaxis (PrEP) with tenofovir disoproxil fumarate-emtricitabine reduced Streptococcus and increased Erysipelotrichaceae in rectal microbiota. [PDF]

, 2018
Daily PrEP is highly effective at preventing HIV-1 acquisition, but risks of long-term tenofovir disoproxil fumarate plus emtricitabine (TDF-FTC) include renal decline and bone mineral density decrease in addition to initial gastrointestinal side effects.
Dubé, Michael P, Lee, Ha Youn, Love, Tanzy MT, Morris, Sheldon R, Park, Sung Yong, Ross, Heather   +5 more
core   +3 more sources

Engineered Tissue Models to Decode Host–Microbiota Interactions

Advanced Science, Volume 12, Issue 23, June 20, 2025.
Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio, Grace E. Callen, Xuesong He, Bruce J. Paster, Hatice Hasturk, Chiara E. Ghezzi   +5 more
wiley   +1 more source