Results 41 to 50 of about 21,361 (182)
AMB ExpressUrinary tract infections (UTI) by antibiotic resistant and virulent K. pneumoniae are a growing concern. Understanding the genome and validating the genomic profile along with pangenome analysis will facilitate surveillance of high-risk clones of K ...
Abhirami Krishnamoorthy Sundaresan +4 more
doaj +1 more source
New Dimensions of Research on Actinomycetes: Quest for Next Generation Antibiotics
Frontiers in Microbiology, 2016 Starting with the discovery of streptomycin, the promise of natural products research on actinomycetes has been captivat¬ing researchers and offered an array of life-saving antibiotics.
Polpass Arul Jose +2 more
doaj +1 more source
Advanced Science, EarlyView.Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang +19 more
wiley +1 more source
Hybrid genome sequence of Cryptococcus neoformans of Indian origin and comparative genome analysis
Scientific ReportsHuman opportunistic fungi C. neoformans are a global health concern as they cause severe pneumonia and cryptococcal meningitis in tropical and subtropical regions.
Jananishree Sathiyamoorthy +1 more
doaj +1 more source
Advanced Science, EarlyView.The genome of Rhodococcus erythropolis D‐1 was analyzed by bioinformatic tools to mine a novel nonribosomal peptide synthetase (NRPS) gene cluster. A nonribosomal peptide analog ZURJC5 associated with the NRPS was chemically synthesized. Through structure‐activity relationship studies, ZURJC28 was ultimately obtained and showed antibacterial activity ...
Keyi Chen +9 more
wiley +1 more source
AGING MEDICINE, EarlyView.This study investigates the regulatory effects of lactulose and polyethylene glycol (PEG) on the composition of gut microbiota in elderly constipation patients with chronic renal insufficiency by comparing the changes in microbial abundance. Both lactulose and PEG significantly modulate the gut microbiota structure, though their specific mechanisms and
Jianxia Ma +10 more
wiley +1 more source
Recent Advances of Actinomycetes [PDF]
Biomolecules, 2021 The discovery and development of actinomycete secondary metabolites (ASMs) have played pivotal roles in the fields of human medicine and its related biotechnology sectors over the past several decades [...]
openaire +3 more sources
Indonesian Journal of Biotechnology, 2015 Marine actinomycetes is a group of bacteria that is highly potential in producing novel bioactive compound. It has unique characteristics and is different from other terrestrial ones.
Camelia Herdini +8 more
doaj +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The role of the cell envelope‐associated Rv0132c/FGD2 from Mycobacterium tuberculosis has long been a subject of debate. Importantly, FGD2 is found only in pathogenic mycobacteria, making it a potential drug target. While some suggest it functions as a glucose‐6‐phosphate dehydrogenase, others propose it acts instead as an F420‐dependent ...
Adewale V. Aderemi +12 more
wiley +1 more source
Effects of herbicides on growth and number of actinomycetes in soil and in vitro [PDF]
Pesticidi i Fitomedicina, 2016 This study was conducted under laboratory conditions to investigate the effects of herbicides (nicosulfuron, metribuzin and glyphosate) on the number of actinomycetes in soil and growth of several isolates of actinomycetes in vitro.
Šantrić Ljiljana +4 more
doaj +1 more source