Results 91 to 100 of about 992,317 (219)

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

open access: yesFEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang   +7 more
wiley   +1 more source

Decoupling in an expanding universe: boundary RG-flow affects initial conditions for inflation

open access: yes, 2004
We study decoupling in FRW spacetimes, emphasizing a Lagrangian description throughout. To account for the vacuum choice ambiguity in cosmological settings, we introduce an arbitrary boundary action representing the initial conditions.
A. Strominger   +41 more
core   +2 more sources

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

open access: yesFEBS Open Bio, EarlyView.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya   +3 more
wiley   +1 more source

PhyLab – a virtual reality laboratory for experiments in physics: a pilot study on intervention effectiveness and gender differences

open access: yesFrontiers in Psychology
IntroductionNew technologies have great potential to facilitate students’ understanding and appreciation of one of the most abstract and challenging school subjects – physics.
Selma Korlat   +6 more
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

DISCUSION ACERCA DE LA UTILIDAD E IMPORTANCIA DE LOS LABORATATORIOS DE FISICA EN LA ENSEÑANZA ACTUAL [PDF]

open access: yesGondola, 2010
n the process of teaching and learning of physics, are referenced various scenarios in which interaction takes place between actors involved in this process. One of the main sites is the laboratory, this has been vital throughout scientific history.
ARNULFO SEGURA, JEIMY LORENA PEREZ
doaj  

On the origin of quantum mechanics

open access: yes, 2005
Action at distance in Newtonian physics is replaced by finite propagation speeds in classical post--Newtonian physics. As a result, the differential equations of motion in Newtonian physics are replaced by functional differential equations, where the ...
Bohr   +38 more
core   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

BV Yang-Mills as a Homotopy Chern-Simons via SFT

open access: yes, 2009
We show explicitly how BV Yang-Mills action emerges as a homotopy generalization of Chern-Simons theory from the algebraic constructions arising from String Field Theory.Comment: LaTeX2e, 22 pages, minor revisions, typos corrected, references added ...
Zeitlin, Anton M.
core   +1 more source

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