Results 91 to 100 of about 4,571,499 (346)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

A compact stellar configuration via gravitation decoupling and minimal geometric deformation

open access: yesNuclear Physics B
The present study reports an investigation of a minimally deformed solution from class one solution embedded into five-dimensional pseudo-Euclidean space, which is the four-dimensional space-time, through a gravitational decoupling approach. Applying the
Samprity Das   +2 more
doaj   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Do students have sufficient knowledge of physics to take marine biology courses? [PDF]

open access: yesBIO Web of Conferences
Physics and biology are two branches of science that have many connections. In marine biology courses, students must have a good basic concept of physics.
Sarkity Dios   +3 more
doaj   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

open access: yesMolecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin   +10 more
wiley   +1 more source

PhyLab – a virtual reality laboratory for experiments in physics: a pilot study on intervention effectiveness and gender differences

open access: yesFrontiers in Psychology
IntroductionNew technologies have great potential to facilitate students’ understanding and appreciation of one of the most abstract and challenging school subjects – physics.
Selma Korlat   +6 more
doaj   +1 more source

PENGEMBANGAN KEMAMPUAN MENYIMPULKAN DAN MENGKOMUNIKASIKAN KONSEP FISIKA MELALUI KEGIATAN PRAKTIKUM FISIKA SEDERHANA

open access: yesJurnal Pendidikan Fisika Indonesia, 2016
Penelitian ini bertujuan untuk mengembangkan keterampilan menyimpulkan dan mengkomunikasikan konsep Fisika siswa kelasXI SMA, materi mekanika fluida dengan kegiatan praktikum Fisika sederhana.
P. Kurnianto, P. Dwijanant, - Khumaedi
doaj   +1 more source

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