Results 211 to 220 of about 5,573,857 (246)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Leveraging blue spaces for public health: Co-creating a whole-system action plan. [PDF]

Public Health Pract (Oxf)
Smith N, Georgiou M, Irving D, Chastin S.   +3 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Korea's National Action Plan on Antimicrobial Resistance: Focusing on the Appropriate Use of Antibiotics. [PDF]

Infect Chemother
Jeong YI, Lee HY, Lee S, Jeong GY, Kim SH, Kim S, Seo SH, Shin NR.   +7 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Enhancing human milk iodine concentration: a data-driven action plan for Latvia. [PDF]

Front Nutr
Aumeistere L, Kovada K, Driksna A, Kozačenko J, Ciproviča I.   +4 more
europepmc   +1 more source

Evaluating Jordan's antimicrobial resistance national action plan (2018-2022) implementation: progress and recommendations. [PDF]

BMC Public Health
Momani S, Alyahya MS, Zayed DK, Tarif AB, Nimri OF, Alshaikh S, Belbiesi A, Al-Tammemi AB.   +7 more
europepmc   +1 more source

Reframing Dementia Prevention Strategies Aligned with the WHO Global Action Plan: A Structured Narrative Review Focusing on Mild Behavioral Impairment. [PDF]

Neurol Int
Angelopoulou E, Papageorgiou S, Papatriantafyllou J.   +2 more
europepmc   +1 more source

Participatory development of Indonesia's national action plan for zero leprosy: strategies and interventions. [PDF]

Front Public Health
Sebong PH, Ferdiana A, Tegu FAR, Harbianto D, Soviandhi R, Sinaga A, Budiawan T, Risnanto AJAY, Sidjabat RT, Yudopuspito T, Mawardi R, Setyawati E, Utarini A.   +12 more
europepmc   +1 more source

Compliance with global action plan on antibiotic prescription and utilization: a multi-facility cross-sectional study in southern Nigeria. [PDF]

BMC Infect Dis
Akpan MR, Eshiet UI, Jackson IL, Etim EO.   +3 more
europepmc   +1 more source