Results 211 to 220 of about 3,519,544 (291)

Editorial: Pediatric infectious diseases and global action plan on AMR. [PDF]

Front Pediatr
Saleem Z.
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Benchmarking Pre-National Action Plan Systemic Antimicrobial Consumption in Tanzania, 1998-2005: A Historical Longitudinal Defined Daily Dose Analysis. [PDF]

Cureus
Sangeda RZ, Kadinde AW, Khea A, Fimbo AM.   +3 more
europepmc   +1 more source

Tackling child sexual exploitation action plan : progress report [PDF]

, 2012

core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Advancing dementia care: a review of Italy's public health response within the WHO Global Action Plan and European strategies. [PDF]

BMJ Public Health
Ancidoni A, Salemme S, Marconi D, Bellomo G, Pani SM, Locuratolo N, Lacorte E, Lombardo FL, Bacigalupo I, Fabrizi E, Canevelli M, Sciancalepore F, Lorenzini P, Palazzesi I, Paggetti A, Della Gatta F, Piscopo P, Salvi E, Zambri F, Di Nolfi A, Palermo V, Sciattella P, Bini C, Mennini FS, Bianchi CBNA, Landoni F, Giannini MA, Di Fiandra T, Vanacore N, National Committee on Dementia of the National Dementia Plan, FONDEM Study Group, National Guideline Working Group.   +31 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

National action plan on antimicrobial resistance in selected Asia-Pacific low- and middle-income countries: Perspectives of One Health stakeholders. [PDF]

One Health
Gunasekara YD, Bailey KE, Scarborough RO, Sri AE, Coppo MJC, Gilkerson JR, Browning GF, Hardefeldt LY.   +7 more
europepmc   +1 more source

Literacy Action Plan: interim progress report, September 2012 [PDF]

, 2012

core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source