Results 1 to 10 of about 772,376 (319)

Carbamazepine Increases the Risk of Sudden Cardiac Arrest by a Reduction of the Cardiac Sodium Current

Frontiers in Cell and Developmental Biology, 2022
Aim: To assess the risk of sudden cardiac arrest (SCA) associated with the use of carbamazepine (CBZ) and establish the possible underlying cellular electrophysiological mechanisms.Methods: The SCA risk association with CBZ was studied in general ...
Lixia Jia, Talip E. Eroglu, Talip E. Eroglu, Ronald Wilders, Arie O. Verkerk, Arie O. Verkerk, Hanno L. Tan, Hanno L. Tan   +7 more
doaj   +1 more source

Taste Receptor Cells Generate Oscillating Receptor Potentials by Activating G Protein-Coupled Taste Receptors

Frontiers in Physiology, 2022
The receptor potentials of taste receptor cells remain unclear. Here, we demonstrate that taste receptor cells generate oscillating depolarization (n = 7) with action potentials in response to sweet, bitter, umami, and salty taste substances.
Yoshiki Nakao, Katsumi Tateno, Yoshitaka Ohtubo   +2 more
doaj   +1 more source

The Impact of Anomalous Diffusion on Action Potentials in Myelinated Neurons

Fractal and Fractional, 2021
Action potentials in myelinated neurons happen only at specialized locations of the axons known as the nodes of Ranvier. The shapes, timings, and propagation speeds of these action potentials are controlled by biochemical interactions among neurons ...
Corina S. Drapaca
doaj   +1 more source

A space-fractional cable equation for the propagation of action potentials in myelinated neurons [PDF]

, 2020
Myelinated neurons are characterized by the presence of myelin, a multilaminated wrapping around the axons formed by specialized neuroglial cells. Myelin acts as an electrical insulator and therefore, in myelinated neurons, the action potentials do not ...
Drapaca, Corina S., Ozdemir, Sahin, Proctor, Elizabeth A.   +2 more
core   +2 more sources

Effect of polycaprolactone/carbon nanotube scaffold implantation along with liposomal ellagic acid in hippocampal synaptogenesis after spinal cord injury [PDF]

Nanomedicine Journal, 2023
Objective(s): Memory and cognition impairments are the most important secondary effects of spinal cord injury (SCI) in the hippocampus. Therefore, the present study aimed to examine the effect of implantation of polycaprolactone/ functionalized multiwall
Arman Abroumand Gholami, Fatemeh Gheybi, Amir Mahdi Molavi, Fatemeh Tahmasebi, Arash Papi, Hamideh Babaloo   +5 more
doaj   +1 more source

Effect of Two Different Rehabilitation Approaches on Pulmonary Functional Tests, Neuromuscular Functions and Quality of Life in Juvenile Myasthenia Gravis: A Randomized Controlled Trial Study

Medicina, 2022
Background and Objectives: Children with juvenile myasthenia gravis have a variety of symptoms, ranging from isolated intermittent ocular complaints to overall muscle weakness with or without respiratory insufficiency. This study aimed to investigate the
Rasha A. Mohamed, El Sayed H. Mohamed, Mohamed A. Basiouny, Ibrahim M. Hamoda, El Sayed M. Hanoura, Elbadawy I. Elhenedi, Abd El Aziz A. Sherief   +6 more
doaj   +1 more source

Light-triggered action potentials in plants

Acta Societatis Botanicorum Poloniae, 2014
Special attention is paid in this paper to the criteria of the light-triggered action potential, namely the all-or-none law, propagation, the occurrence of refractory periods.
Kazimierz Trębacz
doaj   +1 more source

Ventricular voltage‐gated ion channels: Detection, characteristics, mechanisms, and drug safety evaluation

Clinical and Translational Medicine, 2021
Cardiac voltage‐gated ion channels (VGICs) play critical roles in mediating cardiac electrophysiological signals, such as action potentials, to maintain normal heart excitability and contraction.
Lulan Chen, Yue He, Xiangdong Wang, Junbo Ge, Hua Li   +4 more
doaj   +1 more source

The Anti-Epileptic Drugs Lamotrigine and Valproic Acid Reduce the Cardiac Sodium Current

Biomedicines, 2023
Anti-epileptic drugs (AEDs) are associated with increased risk of sudden cardiac death. To establish whether gabapentin, lamotrigine, levetiracetam, pregabalin, and valproic acid reduce the Nav1.5 current, we conducted whole-cell patch-clamp studies to ...
Lixia Jia, Arie O. Verkerk, Hanno L. Tan
doaj   +1 more source

Consequences of converting graded to action potentials upon neural information coding and energy efficiency [PDF]

, 2014
Information is encoded in neural circuits using both graded and action potentials, converting between them within single neurons and successive processing layers. This conversion is accompanied by information loss and a drop in energy efficiency.
A Borst, A Destexhe, A Hasenstaub, A Manwani, A Manwani, A Treves, AA Lazar, AA Lazar, AA Lazar, AL Hodgkin, AS French, B Aguera y Arcas, B Sengupta, B Sengupta, B Sengupta, B Sengupta, B Sengupta, BA Olshausen, BC Carter, Biswa Sengupta, C Koch, C Koch, C Shannon, CC Chow, D Attwell, D Desmaisons, D Lee, DM MacKay, DT Gillespie, E Marder, E Salinas, E Schneidman, E Skaugen, EM Izhikevich, F Theunissen, FA Dodge Jr, G Laurent, G Marsaglia, GG de Polavieja, H Alle, H Alle, J Haag, JA White, JA White, JC Rekling, JC Skou, JD Victor, JD Victor, JE Niven, JE Niven, JE Niven, JE Niven, JE Niven, Jeremy Edward Niven, K Koch, M Juusola, M Matsumoto, M Pinsker, M Stemmler, MB Kennel, ME Larkum, MH Kole, MN Shadlen, MS Grubb, MV Srinivasan, NJ Lenn, O Bernander, Olaf Sporns, PG Lillywhite, PN Steinmetz, R Guttman, R Sarpeshkar, RA DiCaprio, RRdR van Steveninck, S Curti, S Laughlin, SB Laughlin, Simon Barry Laughlin, SP Strong, SR Williams, TJ Gawne, V Prelov, W Singer, Y Shu, ZF Mainen   +84 more
core   +3 more sources