Results 1 to 10 of about 14,230,890 (402)

Effect of polycaprolactone/carbon nanotube scaffold implantation along with liposomal ellagic acid in hippocampal synaptogenesis after spinal cord injury [PDF]

Nanomedicine Journal, 2023
Objective(s): Memory and cognition impairments are the most important secondary effects of spinal cord injury (SCI) in the hippocampus. Therefore, the present study aimed to examine the effect of implantation of polycaprolactone/ functionalized multiwall
Arman Abroumand Gholami, Fatemeh Gheybi, Amir Mahdi Molavi, Fatemeh Tahmasebi, Arash Papi, Hamideh Babaloo   +5 more
doaj   +1 more source

Carbamazepine Increases the Risk of Sudden Cardiac Arrest by a Reduction of the Cardiac Sodium Current

Frontiers in Cell and Developmental Biology, 2022
Aim: To assess the risk of sudden cardiac arrest (SCA) associated with the use of carbamazepine (CBZ) and establish the possible underlying cellular electrophysiological mechanisms.Methods: The SCA risk association with CBZ was studied in general ...
Lixia Jia, Talip E. Eroglu, Talip E. Eroglu, Ronald Wilders, Arie O. Verkerk, Arie O. Verkerk, Hanno L. Tan, Hanno L. Tan   +7 more
doaj   +1 more source

Taste Receptor Cells Generate Oscillating Receptor Potentials by Activating G Protein-Coupled Taste Receptors

Frontiers in Physiology, 2022
The receptor potentials of taste receptor cells remain unclear. Here, we demonstrate that taste receptor cells generate oscillating depolarization (n = 7) with action potentials in response to sweet, bitter, umami, and salty taste substances.
Yoshiki Nakao, Katsumi Tateno, Yoshitaka Ohtubo   +2 more
doaj   +1 more source

Tonic Control of Secretory Acid Sphingomyelinase Over Ventral Hippocampal Synaptic Transmission and Neuron Excitability

Frontiers in Cellular Neuroscience, 2021
The acid sphingomyelinase (ASM) converts sphingomyelin into ceramide. Recent work has advanced the ASM/ceramide system as a major player in the pathogenesis of major depressive disorder (MDD).
Chih-Hung Lin, Chih-Hung Lin, Johannes Kornhuber, Fang Zheng, Christian Alzheimer   +4 more
doaj   +1 more source

A Non-local Model of the Propagation of Action Potentials in Myelinated Neurons

Emerging Science Journal, 2020
Myelinated neurons are characterized by the presence of myelin, a multilaminated wrapping around the axons formed by specialized neuroglial cells. Myelin acts as an electrical insulator and therefore, in myelinated neurons, the action potentials do not ...
Corina Stefania Drapaca, Sahin Ozdemir, Elizabeth Proctor   +2 more
doaj   +1 more source

A brief exposure to toluene vapor alters the intrinsic excitability of D2 medium spiny neurons in the rat ventral striatum

Frontiers in Neuroscience, 2023
Although volatile organic solvents such as toluene are used for commercial and industrial uses, they are often voluntarily inhaled for their intoxicating and euphoric effects.
Michael Okas, Abigail Kastner, Dominic Gioia, John J. Woodward   +3 more
doaj   +1 more source

The Impact of Anomalous Diffusion on Action Potentials in Myelinated Neurons

Fractal and Fractional, 2021
Action potentials in myelinated neurons happen only at specialized locations of the axons known as the nodes of Ranvier. The shapes, timings, and propagation speeds of these action potentials are controlled by biochemical interactions among neurons ...
Corina S. Drapaca
doaj   +1 more source

Parametric analysis of the ionic concentrations effects in the behavior of the sinoatrial node

Revista Facultad de Ingeniería Universidad de Antioquia, 2013
A sensibility study on the effect of ionic concentrations in the behavior of the sinoatrial node was carried out. The study was based on the model proposed by H. Zhang, A. V. Holden and M.R. Boyett.
Daniel Alfonso Sierra, Oscar Leonel Rueda, Carlos Rodrigo Correa   +2 more
doaj   +1 more source

Consequences of converting graded to action potentials upon neural information coding and energy efficiency [PDF]

, 2014
Information is encoded in neural circuits using both graded and action potentials, converting between them within single neurons and successive processing layers. This conversion is accompanied by information loss and a drop in energy efficiency.
A Borst, A Destexhe, A Hasenstaub, A Manwani, A Manwani, A Treves, AA Lazar, AA Lazar, AA Lazar, AL Hodgkin, AS French, B Aguera y Arcas, B Sengupta, B Sengupta, B Sengupta, B Sengupta, B Sengupta, BA Olshausen, BC Carter, Biswa Sengupta, C Koch, C Koch, C Shannon, CC Chow, D Attwell, D Desmaisons, D Lee, DM MacKay, DT Gillespie, E Marder, E Salinas, E Schneidman, E Skaugen, EM Izhikevich, F Theunissen, FA Dodge Jr, G Laurent, G Marsaglia, GG de Polavieja, H Alle, H Alle, J Haag, JA White, JA White, JC Rekling, JC Skou, JD Victor, JD Victor, JE Niven, JE Niven, JE Niven, JE Niven, JE Niven, Jeremy Edward Niven, K Koch, M Juusola, M Matsumoto, M Pinsker, M Stemmler, MB Kennel, ME Larkum, MH Kole, MN Shadlen, MS Grubb, MV Srinivasan, NJ Lenn, O Bernander, Olaf Sporns, PG Lillywhite, PN Steinmetz, R Guttman, R Sarpeshkar, RA DiCaprio, RRdR van Steveninck, S Curti, S Laughlin, SB Laughlin, Simon Barry Laughlin, SP Strong, SR Williams, TJ Gawne, V Prelov, W Singer, Y Shu, ZF Mainen   +84 more
core   +3 more sources

Ventricular voltage‐gated ion channels: Detection, characteristics, mechanisms, and drug safety evaluation

Clinical and Translational Medicine, 2021
Cardiac voltage‐gated ion channels (VGICs) play critical roles in mediating cardiac electrophysiological signals, such as action potentials, to maintain normal heart excitability and contraction.
Lulan Chen, Yue He, Xiangdong Wang, Junbo Ge, Hua Li   +4 more
doaj   +1 more source