Results 11 to 20 of about 4,325 (209)

Large and fast human pyramidal neurons associate with intelligence

eLife, 2018
It is generally assumed that human intelligence relies on efficient processing by neurons in our brain. Although grey matter thickness and activity of temporal and frontal cortical areas correlate with IQ scores, no direct evidence exists that links ...
Natalia A Goriounova, Djai B Heyer, René Wilbers, Matthijs B Verhoog, Michele Giugliano, Christophe Verbist, Joshua Obermayer, Amber Kerkhofs, Harriët Smeding, Maaike Verberne, Sander Idema, Johannes C Baayen, Anton W Pieneman, Christiaan PJ de Kock, Martin Klein, Huibert D Mansvelder   +15 more
doaj   +1 more source

Intraoperative Microelectrode Recordings in Substantia Nigra Pars Reticulata in Anesthetized Rats

Frontiers in Neuroscience, 2020
The Substantia Nigra pars reticulata (SNr) is a promising target for deep brain stimulation (DBS) to treat the gait and postural disturbances in Parkinson’s disease (PD).
Hanyan Li, George C. McConnell
doaj   +1 more source

Modulation of Functional Connectivity Between Dopamine Neurons of the Rat Ventral Tegmental Area in vitro

Frontiers in Integrative Neuroscience, 2019
Micro Electrode Arrays were used to simultaneously record spontaneous extracellular action potentials from 10 to 30 dopamine neurons in acute brain slices from the lateral Ventral Tegmental Area (VTA) of the rat.
Luuk van der Velden, Martin A. Vinck, Taco R. Werkman, Wytse J. Wadman   +3 more
doaj   +1 more source

Estimation of Multiple Cardiac Cells’ Action Potentials From Extracellular Field Potentials

Vìsnik Nacìonalʹnogo Tehnìčnogo Unìversitetu Ukraïni Kììvsʹkij Polìtehnìčnij Ìnstitut: Serìâ Radìotehnìka, Radìoaparatobuduvannâ, 2023
Modern biomedical technologies use a combination of microelectrode array (MEA) systems and artificially grown cells to study disease mechanisms and test drug effects.
M. O. Shpotak, N. H. Ivanushkina, K. O. Ivanko, Y. V. Prokopenko   +3 more
doaj   +1 more source

Effects of sugammadex and rocuronium on electro-mechanical activity of cardiac myocytes [PDF]

Korean Journal of Anesthesiology
Background Sugammadex reverses the effects of steroidal neuromuscular-blocking agents, such as rocuronium, by encapsulating these agents. Its cardiovascular adverse effects include QTc prolongation, hypotension, bradycardia, atrioventricular block ...
Oguzhan Arun, Nihal Ozturk, Orhan Erkan, Semir Ozdemir, Funda Arun, Sırma Basak Yanardag, Murat Ayaz   +6 more
doaj   +1 more source

A brief exposure to toluene vapor alters the intrinsic excitability of D2 medium spiny neurons in the rat ventral striatum

Frontiers in Neuroscience, 2023
Although volatile organic solvents such as toluene are used for commercial and industrial uses, they are often voluntarily inhaled for their intoxicating and euphoric effects.
Michael Okas, Abigail Kastner, Dominic Gioia, John J. Woodward   +3 more
doaj   +1 more source

Repolarization Alternans and Ventricular Arrhythmia in a Repaired Tetralogy of Fallot Animal Model

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Background Ventricular arrhythmia is an important cause of late death in patients with repaired tetralogy of Fallot (rTOF). By using an rTOF canine model, we investigated the role of repolarization alternans and its electrophysiological mechanisms ...
Shuenn‐Nan Chiu, Chia‐Ti Tsai, Lian‐Yu Lin, Shu‐Chien Huang, Yih‐Sharng Chen, Jou‐Kou Wang, Mei‐Hwan Wu, Ling‐Ping Lai, Jiunn‐Lee Lin   +8 more
doaj   +1 more source

The Soliton and the Action Potential – Primary Elements Underlying Sentience

Frontiers in Physiology, 2018
At present the neurological basis of sentience is poorly understood and this problem is exacerbated by only a partial knowledge of how one of the primary elements of sentience, the action potential, actually works.
Andrew S. Johnson, Andrew S. Johnson, William Winlow, William Winlow, William Winlow   +4 more
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Tonic Control of Secretory Acid Sphingomyelinase Over Ventral Hippocampal Synaptic Transmission and Neuron Excitability

Frontiers in Cellular Neuroscience, 2021
The acid sphingomyelinase (ASM) converts sphingomyelin into ceramide. Recent work has advanced the ASM/ceramide system as a major player in the pathogenesis of major depressive disorder (MDD).
Chih-Hung Lin, Chih-Hung Lin, Johannes Kornhuber, Fang Zheng, Christian Alzheimer   +4 more
doaj   +1 more source

A Comparative Study of Cell Specific Effects of Systemic and Volatile Anesthetics on Identified Motor Neurons and Interneurons of Lymnaea stagnalis (L.), Both in the Isolated Brain and in Single Cell Culture

Frontiers in Physiology, 2019
1. A comparative descriptive analysis of systemic (sodium pentobarbital, sodium thiopentone, ketamine) and volatile (halothane, isoflurane, enflurane) general anesthetics revealed important differences in the neuronal responses of identified motor ...
Hadi Fathi Moghadam, Talay Yar, Munir M. Qazzaz, Ibrahim Abdelrazig Ahmed, William Winlow, William Winlow, William Winlow   +6 more
doaj   +1 more source