Results 21 to 30 of about 3,738,124 (301)
Cardiac voltage‐gated ion channels (VGICs) play critical roles in mediating cardiac electrophysiological signals, such as action potentials, to maintain normal heart excitability and contraction.
Lulan Chen +4 more
doaj +1 more source
The Anti-Epileptic Drugs Lamotrigine and Valproic Acid Reduce the Cardiac Sodium Current
Anti-epileptic drugs (AEDs) are associated with increased risk of sudden cardiac death. To establish whether gabapentin, lamotrigine, levetiracetam, pregabalin, and valproic acid reduce the Nav1.5 current, we conducted whole-cell patch-clamp studies to ...
Lixia Jia, Arie O. Verkerk, Hanno L. Tan
doaj +1 more source
Biophysics of Extracellular Action Potentials [PDF]
The goal of this thesis is to analyze the generation of single unit extracellular action potentials (EAPs), and to explore pertinent issues in the interpretation of EAP recordings.
Gold, Carl
core +1 more source
Large and fast human pyramidal neurons associate with intelligence
It is generally assumed that human intelligence relies on efficient processing by neurons in our brain. Although grey matter thickness and activity of temporal and frontal cortical areas correlate with IQ scores, no direct evidence exists that links ...
Natalia A Goriounova +15 more
doaj +1 more source
Micro Electrode Arrays were used to simultaneously record spontaneous extracellular action potentials from 10 to 30 dopamine neurons in acute brain slices from the lateral Ventral Tegmental Area (VTA) of the rat.
Luuk van der Velden +3 more
doaj +1 more source
Intraoperative Microelectrode Recordings in Substantia Nigra Pars Reticulata in Anesthetized Rats
The Substantia Nigra pars reticulata (SNr) is a promising target for deep brain stimulation (DBS) to treat the gait and postural disturbances in Parkinson’s disease (PD).
Hanyan Li, George C. McConnell
doaj +1 more source
Estimation of Multiple Cardiac Cells’ Action Potentials From Extracellular Field Potentials
Modern biomedical technologies use a combination of microelectrode array (MEA) systems and artificially grown cells to study disease mechanisms and test drug effects.
M. O. Shpotak +3 more
doaj +1 more source
Event-Related Brain Potentials for Goal-Related Power Grips [PDF]
Westerholz J, Schack T, Koester D. Event-Related Brain Potentials for Goal-Related Power Grips. PLoS ONE. 2013;8(7): e68501.Recent research has shown that neurophysiological activation during action planning depends on the orientation to initial or final
Jan Westerholz (429286) +11 more
core +1 more source
Effects of sugammadex and rocuronium on electro-mechanical activity of cardiac myocytes [PDF]
Background Sugammadex reverses the effects of steroidal neuromuscular-blocking agents, such as rocuronium, by encapsulating these agents. Its cardiovascular adverse effects include QTc prolongation, hypotension, bradycardia, atrioventricular block ...
Oguzhan Arun +6 more
doaj +1 more source
Repolarization Alternans and Ventricular Arrhythmia in a Repaired Tetralogy of Fallot Animal Model
Background Ventricular arrhythmia is an important cause of late death in patients with repaired tetralogy of Fallot (rTOF). By using an rTOF canine model, we investigated the role of repolarization alternans and its electrophysiological mechanisms ...
Shuenn‐Nan Chiu +8 more
doaj +1 more source

