Results 11 to 20 of about 14,230,890 (402)

Emerging Roles of the Membrane Potential: Action Beyond the Action Potential [PDF]

open access: yesFrontiers in Physiology, 2018
Whilst the phenomenon of an electrical resting membrane potential (RMP) is a central tenet of biology, it is nearly always discussed as a phenomenon that facilitates the propagation of action potentials in excitable tissue, muscle, and nerve. However, as
Lina Abdul Kadir   +2 more
semanticscholar   +7 more sources

Full-field interferometric imaging of propagating action potentials [PDF]

open access: yesLight: Science & Applications, 2018
Currently, cellular action potentials are detected using either electrical recordings or exogenous fluorescent probes that sense the calcium concentration or transmembrane voltage.
Tong Ling   +7 more
semanticscholar   +1 more source

Dendritic action potentials and computation in human layer 2/3 cortical neurons

open access: yesScience, 2020
Human dendrites are special A special developmental program in the human brain drives the disproportionate thickening of cortical layer 2/3. This suggests that the expansion of layer 2/3, along with its numerous neurons and their large dendrites, may ...
A. Gidon   +8 more
semanticscholar   +1 more source

Cardiac Transmembrane Ion Channels and Action Potentials: Cellular Physiology and Arrhythmogenic Behavior.

open access: yesPhysiological Reviews, 2020
Cardiac arrhythmias are among the leading causes of mortality. They often arise from alterations in the electrophysiological properties of cardiac cells, and their underlying ionic mechanisms.
A. Varró   +6 more
semanticscholar   +1 more source

An action potential initiation mechanism in distal axons for the control of dopamine release

open access: yesScience, 2022
Information flow in neurons proceeds by integrating inputs in dendrites, generating action potentials near the soma, and releasing neurotransmitters from nerve terminals in the axon.
Changliang Liu   +7 more
semanticscholar   +1 more source

Potential Antiviral Action of Alkaloids [PDF]

open access: yesMolecules, 2022
Viral infections and outbreaks have become a major concern and are one of the main causes of morbidity and mortality worldwide. The development of successful antiviral therapeutics and vaccines remains a daunting challenge. The discovery of novel antiviral agents is a public health emergency, and extraordinary efforts are underway globally to identify ...
Frage L. Abookleesh   +2 more
openaire   +3 more sources

Flexible graphene transistors for recording cell action potentials [PDF]

open access: yes, 2016
Graphene solution-gated field-effect transistors (SGFETs) are a promising platform for the recording of cell action potentials due to the intrinsic high signal amplification of graphene transistors. In addition, graphene technology fulfills important key
Benno M. Blaschke   +7 more
semanticscholar   +1 more source

The Anti-Epileptic Drugs Lamotrigine and Valproic Acid Reduce the Cardiac Sodium Current

open access: yesBiomedicines, 2023
Anti-epileptic drugs (AEDs) are associated with increased risk of sudden cardiac death. To establish whether gabapentin, lamotrigine, levetiracetam, pregabalin, and valproic acid reduce the Nav1.5 current, we conducted whole-cell patch-clamp studies to ...
Lixia Jia, Arie O. Verkerk, Hanno L. Tan
doaj   +1 more source

Intracellular recording of cardiomyocyte action potentials with nanopatterned volcano-shaped microelectrode arrays.

open access: yesNano letters (Print), 2019
Micro-nanotechnology based multielectrode arrays have led to remarkable progress in the field of transmembrane voltage recording of excitable cells. However, providing long-term opto- or electroporation free intracellular access remains a considerable ...
B. Desbiolles   +4 more
semanticscholar   +1 more source

Modulation of Functional Connectivity Between Dopamine Neurons of the Rat Ventral Tegmental Area in vitro

open access: yesFrontiers in Integrative Neuroscience, 2019
Micro Electrode Arrays were used to simultaneously record spontaneous extracellular action potentials from 10 to 30 dopamine neurons in acute brain slices from the lateral Ventral Tegmental Area (VTA) of the rat.
Luuk van der Velden   +3 more
doaj   +1 more source

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