Results 211 to 220 of about 458,032 (263)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source
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Actionness-Assisted Recognition of Actions

2015 IEEE International Conference on Computer Vision (ICCV), 2015
We elicit from a fundamental definition of action low-level attributes that can reveal agency and intentionality. These descriptors are mainly trajectory-based, measuring sudden changes, temporal synchrony, and repetitiveness. The actionness map can be used to localize actions in a way that is generic across action and agent types. Furthermore, it also
Ye Luo, Loong-Fah Cheong, An Tran
openaire   +1 more source

Action recognition with prototypes

2017 25th Signal Processing and Communications Applications Conference (SIU), 2017
Action recognition is a widely studied problem and many solutions have been introduced over the years. However, classification with weakly-labeled large scale web data continues to be a challenge due to the noisy content. In this study, we utilize a representation method that is based on selected distinctive exemplars, motivated by the success of ...
Ozge Yalcinkaya, Pinar Duygulu
openaire   +1 more source

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