Results 111 to 120 of about 16,184,590 (268)

Assessment of Thrombin Generation in Pediatric Patients on Extracorporeal Life Support: Impact of Bivalirudin and Other Anticoagulants

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Bivalirudin is an alternative anticoagulant to heparin and is widely used in pediatric extracorporeal life support (ECLS). Its activity is monitored using activated partial thromboplastin time (aPTT) and/or more specific tests such as plasma‐diluted thrombin time (dTT).
Vadim Kostousov, Karen Bruzdoski, Amir Navaei, Jun Teruya   +3 more
wiley   +1 more source

Activated Partial Thromboplastin Time Abnormality in Patients with Cholangiocarcinoma

Clinical and Applied Thrombosis/Hemostasis, 2004
Cholangiocarcinoma can be detected worldwide, but is most common in tropical areas where crowded living conditions and poor sanitation exist. This infection can demonstrate a wide spectrum of clinical presentations from no complaints to arrest. Similar to the other liver diseases, the activated partial thromboplastin time abnormality can be seen in the
openaire   +2 more sources

Performance Assessment of Staclot‐LA Assay on Fully Automated Coagulation Analyser for Lupus Anticoagulant Testing Using Internal and External Quality Controls

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction It is recommended to detect lupus anticoagulant (LA) using two phospholipid‐dependent clotting assays, including a LA‐sensitive activated partial‐thromboplastin‐time (aPTT). Among these reagents, Staclot‐LA assay is performed on a mixture of test and normal plasma with and without hexagonal phase phospholipids.
V. Siguret, G. Jourdi, S. Melicine, L. Goubeau, Q. Pomorski, B. Joly‐Laffargue, A. Stepanian, M. Delrue, C. Bon, P. Meijer, E. Curis   +10 more
wiley   +1 more source

Is It Time to Raise the Threshold for Critically Low Fibrinogen? Insights From a Retrospective, Consecutive‐Case Cohort Study of Low Fibrinogen due to Various Causes

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Fibrinogen deficiency is an important coagulation abnormality, with diverse causes. Methods A consecutive‐case cohort study of adult and pediatric patients with low Clauss fibrinogen at four acute care hospitals was undertaken to explore findings, causes, and predictors of outcomes, including the optimal fibrinogen critical value ...
Natalie Mathews, Subia Tasneem, Mana Al Dawsari, Keona Pang, Yasmeen Abulkhair, Guillame Paré, Siraj Mithoowani, Catherine P. M. Hayward   +7 more
wiley   +1 more source

The importance of the determination of activated partial thromboplastin time and partial thromboplastin sensitivity compared to the lupus anticoagulant, deficiency of coagulation factors and heparin. [PDF]

, 2011
The importance of the determination of activated partial thromboplastin time and partial thromboplastin sensitivity compared to the lupus anticoagulant, deficiency of coagulation factors and heparin Dagmar Drábková Abstract Activated partial ...
Drábková, Dagmar
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Functional Assessment of Platelet‐Derived Phospholipid Activity in Pooled Normal Plasmas by Low‐Phospholipid Thrombin Generation Assay and Its Impact on Lupus Anticoagulant Mixing Tests

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Pooled normal plasma (PNP) used for lupus anticoagulant (LA) mixing tests may carry platelet‐derived phospholipid (PL) activity introduced during freezing/lyophilization, potentially attenuating LA‐mediated prolongation of clotting times.
Osamu Kumano, Masato Matsuda, Mino Sakata, Osamu Maruyama   +3 more
wiley   +1 more source

The relationship between different anticoagulation monitoring indicators and heparin doses in adult patients with extracorporeal cardiopulmonary resuscitation

Frontiers in Cardiovascular Medicine
ObjectivesAchieving optimal systemic anticoagulation in patients undergoing extracorporeal membrane oxygenation (ECMO) requires precise titration, posing a significant clinical challenge.
Jiali Yao, Jiali Yao, Cong Jin, Tianxing Du, Huizhen Yu, Huizhen Yu   +5 more
doaj   +1 more source

WTAP‐mediated m6A RNA methylation promotes diabetic foot ulcer healing under negative pressure wound therapy

Journal of Diabetes Investigation, EarlyView.
NPWT significantly increases the suppressed WTAP and m6A levels in DFU patients, correlating directly with better 4‐week healing outcomes. In vitro, negative pressure reverses high‐glucose‐induced WTAP downregulation, restoring the cell proliferation and migration necessary for wound repair.
Yutong Li, Wenhua Chen, Jianhao Lu, Xiaoyue Lin, Ying Tang, Jiaxu Li, Mingwei Chen   +6 more
wiley   +1 more source

Oral Soft Tissue Biopsy in Patients Receiving Direct Oral Anticoagulants: A Prospective Cohort Study on Bleeding Outcomes

Oral Diseases, EarlyView.
ABSTRACT Background Direct oral anticoagulants (DOACs) are the first‐line therapy for stroke prevention in non‐valvular atrial fibrillation and venous thromboembolism. While evidence supports their continuation during routine dental procedures such as tooth extractions, data on oral soft tissue biopsies remain limited.
Rossana Izzetti, Chiara Cinquini, Antonio Barone, Marco Nisi   +3 more
wiley   +1 more source

Effect Of Hydroxyethyl Starch 200/0.5 On Von Willebrand Factor Serum Level And Activated Partial Thromboplastin Time (APTT) [PDF]

, 2015
Hydroxyethyl starch (HES) is a colloid administered frequently for intravascular volume expansion during perioperative period. Impairment of haemostasis have been reported during HES administration, but the volume of solution administered was usually ...
Dewi Wara Shinta, Budi Suprapti, Junaidi Khotib, Eddy Rahardjo, Sarah Puspita Atmaja, Mahardian Rahmadi   +5 more
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