Results 1 to 10 of about 32,297 (224)

Differences in the Composition of Activated Partial Thromboplastin Time (APTT) Reagents Affect Clot Waveform Analysis. [PDF]

Yonago Acta Med, 2022
Clot waveform analysis (CWA) based on activated partial thromboplastin time (APTT) is a useful assay for hemostasis. However, the effects of activators and phospholipid conditions on CWA have not been adequately investigated. Therefore, we characterized CWA using four different APTT reagents.We used 39 archived plasma samples from patients with ...
Kato K, Hatayama Y, Shimohiro H, Ichikawa H, Fukuda T.   +4 more
europepmc   +5 more sources

Influence of factor XII deficiency on activated partial thromboplastin time (aPTT) in critically ill patients. [PDF]

J Thromb Thrombolysis, 2019
FXII deficiency results in spontaneous prolongation of activated partial thromboplastin time (aPTT), which is widely used to monitor thromboprophylaxis. Misinterpretation of spontaneously prolonged aPTT may result in omission of thromboembolic treatment or even unnecessary transfusion of blood products.
Bachler M, Niederwanger C, Hell T, Höfer J, Gerstmeyr D, Schenk B, Treml B, Fries D.   +7 more
europepmc   +7 more sources

Reporting of activated partial thromboplastin time (aPTT): Could we achieve better comparability of the results? [PDF]

Biochem Med (Zagreb), 2021
Activated partial thromboplastin time (aPTT) is determined and reported as clotting time in seconds aPTT(s), but it is presumed that reporting results as patient-to-normal clotting time ratio, aPTT(r), could minimize within-laboratory variability. The aim of study was to investigate differences in reporting aPTT results that can affect comparability of
Bronić A, Margetić S, Coen Herak D, Milić M, Krešić B, Radišić Biljak V, Leniček Krleža J.   +6 more
europepmc   +7 more sources

A Case of Severe Prekallikrein Deficiency Manifesting as Isolated Activated Partial Thromboplastin Time (aPTT) Prolongation. [PDF]

Cureus
We present the case of a 54-year-old female who was admitted to the medicine service for a left foot ulcer with cellulitis requiring hallux amputation. Pre-surgical laboratory findings were significant for an isolated elevation in activated partial thromboplastin time (aPTT).
Viswanathan D, Sivanandam A, Yeung V.
europepmc   +3 more sources

Prediction of Poor Outcomes in Patients with Colorectal Cancer: Elevated Preoperative Prothrombin Time (PT) and Activated Partial Thromboplastin Time (APTT) [PDF]

Cancer Management and Research, 2020
Lin Zhang,1,2,* Juan Ye,2– 4,* Qiuyun Luo,2 Miaohuan Kuang,1 Minjie Mao,1 Shuqin Dai,1 Xueping Wang1 1Department of Clinical Laboratory, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation
Zhang L, Ye J, Luo Q, Kuang M, Mao M, Dai S, Wang X   +6 more
doaj   +2 more sources

Effect of Hyperthermia on Prothrombin Time (PT), International Normalized Ratio (INR), and Activated Partial Thromboplastin Time (APTT). [PDF]

Cureus
Background Coagulation testing in the laboratory is performed at 37°C. However, this in vitro testing may not reflect the in vivo pathophysiology affecting coagulation factors in clinical conditions that cause hyperthermia. This study aimed to evaluate the effect of hyperthermia on prothrombin time (PT), international normalized ratio (INR), and ...
Devi J, Kakkar N, Sharma A.
europepmc   +3 more sources

Laboratory Identification of Lupus Anticoagulant (LA) Using Different Activated Partial Thromboplastin Time (APTT) Assays. [PDF]

Int J Lab Hematol
ABSTRACT Introduction The International Society of Thrombosis and Hemostasis (ISTH) guidelines suggest a three‐step evaluation for the detection of lupus anticoagulant (LA), including screening, mixing, and confirmation.
Barion BG, Stefanello B, de Paula MLSA, Saraiva TS, Villaça PR, Rocha V, Orsi FA, da Rocha TRF.   +7 more
europepmc   +4 more sources

Age-dependent patterns of D-dimer and APTT for VTE in severe pneumonia: a multicenter retrospective study [PDF]

Thrombosis Journal
Objective To investigate age-stratified patterns of admission D-dimer and activated partial thromboplastin time (APTT) and their complementary value for venous thromboembolism (VTE) detection in severe community-acquired pneumonia (SCAP).
Qiuhong Wen, Shumin Chen, Lingling Hong, Jiayi Lin, Jiashun Li, Weizhi Liang, Qian jiang, Ni Ren, Nuofu Zhang, Ning Lai, Chunli Liu   +10 more
doaj   +2 more sources

Interferensi Hematokrit Tinggi Terhadap Pemeriksaan Prothrombin Time dan Activated Partial Thromboplastin Time

Majalah Kedokteran Andalas, 2021
Pendahuluan: Hematokrit (Ht) yang tinggi merupakan salah satu faktor interferensi pemeriksaan hemostasis yang sering luput dari perhatian. Penurunan volume plasma relatif terhadap keseluruhan darah pada hematokrit yang tinggi akan meningkatkan rasio ...
Hevrina Yufani, Zelly Dia Rofinda
doaj   +1 more source

Study of Basic Coagulation Parameters among HIV Patients in Correlation to CD4 Counts and Art Status [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: HIV infection is known to cause coagulation abnormalities by various mechanism, especially during its late course. Aim: The objective of this study is to analyse platelet count, prothrombin time and activated partial thromboplastin time
R Thulasi Raman, D Manimaran, Praveen Rachakatla, K Bharathi, Tameem Afroz, Radha Sagar   +5 more
doaj   +1 more source