Results 71 to 80 of about 84,070 (269)

Evaluation of the effect of apixaban using a viscoelastic coagulation assay with Russell’s viper venom reagent

JA Clinical Reports, 2021
Background Conventional coagulation tests, such as prothrombin time and activated partial thromboplastin time, are not sensitive to anticoagulation by apixaban. We evaluated the antithrombotic effect of apixaban using a Russell viper venom (RVV) test for
Kaoru Suzuki, Nobuyuki Katori, Yoshihiro Kimura, Takako Terui, Hiroshi Sunaga, Shunsuke Kobayashi, Shoichi Uezono   +6 more
doaj   +1 more source

Relationship between plasma dabigatran concentration and activated partial thromboplastin time in Japanese patients with non‐valvular atrial fibrillation

Journal of Arrhythmia, 2015
Activated partial thromboplastin time (aPTT) is recommended for monitoring anticoagulant activity in dabigatran‐treated patients; however, there are limited data in Japanese patients.
D. Shimomura, Y. Nakagawa, H. Kondo, T. Tamura, M. Amano, Yukiko Hayama, N. Onishi, Y. Tamaki, M. Miyake, K. Kaitani, C. Izumi, M. Hayashida, A. Fukuda, Fumihiko Nakamura, S. Kawano   +14 more
semanticscholar   +1 more source

Use of the Activated Partial Thromboplastin Time for Heparin Monitoring [PDF]

American Journal of Clinical Pathology, 2001
The objectives of the present study were to evaluate the relationship between heparin concentration and activated partial thromboplastin time (aPTT) results, define a heparin concentration-derived therapeutic range for each aPTT instrument, compare aPTT- and heparin concentration-guided dosage adjustment decisions, and compare laboratory- and bedside ...
M A, Smythe, J M, Koerber, S J, Westley, S N, Nowak, R L, Begle, M, Balasubramaniam, J C, Mattson   +6 more
openaire   +2 more sources

Resolving a Complex Neonatal Phenotype by Rapid Trio Whole‐Genome Sequencing: A De Novo 11q14.3–q22.3 Deletion and a Splicing‐Altering Synonymous ANK1 Variant

Journal of Clinical Laboratory Analysis, EarlyView.
Clinical utility of trio WGS and time metrics in a neonate with congenital anomalies and hemolytic anemia. ABSTRACT Background Neonates with complex and evolving phenotypes often lack sufficiently specific clinical features to guide targeted genetic testing.
Hyun‐Woo Lee, Ja‐Hyun Jang, Beom Hee Lee, Hee‐Jeong Youk, Eun Sun Kim, Kee Hyun Cho, Yun Sil Chang, Heui Seung Jo, Mi‐Ae Jang   +8 more
wiley   +1 more source

Preliminary Evaluation of a Novel Lupus Anticoagulant Activity Assay Unaffected by Anticoagulants

Journal of Clinical Laboratory Analysis, EarlyView.
A novel one‐step lupus anticoagulant (LA) assay based on the LA‐sensitivity ratio (LA‐SR) was developed to simplify diagnostic testing and reduce potential interference from anticoagulants. The LA‐SR method showed good agreement with guideline‐based LA testing (dRVVT and/or LA‐sensitive APTT) for the detection of LA and demonstrated limited influence ...
Ayu Hidaka, Risa Kaneshige, Seika Nakamura, Yukari Motoki, Junzo Nojima   +4 more
wiley   +1 more source

Activated Partial Thromboplastin Time Clot Waveform Analysis In Hemophilia A

Journal of Taibah University Medical Sciences, 2023
Maha Said, Amani Jabri, Ons Ghali, Fatma Ben Lakhal, Sarra Fekih Salem, Emna Gouider, Wijdene El Borgi   +6 more
doaj   +1 more source

Evaluation of anticoagulant and thrombolytic activity of Berberis orthobotrys in animal model

Bangladesh Journal of Pharmacology, 2018
Fundamental to this research was the evaluation of anticoagulant and thrombolytic potential of Berberis orthobotrys using clotting time, prothrombin time and activated partial thromboplastin time performed at 2.5, 5, 10% concentration.
. Alamgeer, Mahpara Tarar, Umme Habiba Hasan, Muhammad Saleem   +3 more
doaj   +1 more source

Early prediction of acute kidney injury in traumatic and non‐traumatic rhabdomyolysis using an interpretable machine learning model: A multicenter study with external validation

Journal of Intelligent Medicine, EarlyView.
Abstract Acute kidney injury (AKI) is a common and severe complication of rhabdomyolysis (RM), and early risk stratification remains challenging because of its multifactorial and heterogeneous nature. We developed and externally validated an interpretable machine learning (ML) model for early prediction of AKI in RM across traumatic and non‐traumatic ...
Chunli Liu, Jie Shi, Fengjuan Wang, Liang Ma, Huangang Hu, Li Zhang, Jie Song, Heng Jin, Dingwei Yang, Xiaoqin Guo, Haojun Fan, Qi Lv   +11 more
wiley   +1 more source

A Refractory Leg Skin Ulcer Associated With Multiple Myeloma Successfully Treated With Plasma Exchange, Lenalidomide, and Dexamethasone

JEADV Clinical Practice, EarlyView.
ABSTRACT Multiple myeloma (MM) is a malignant plasma cell disorder that primarily presents with CRAB symptoms (calcium elevation, renal failure, anemia, and bone abnormalities). In rare cases, MM manifests with systemic complications like skin ulcers, which present management challenges. Here, we report a 78‐year‐old Japanese man with MM and refractory
Naoko Hattori, Yutaka Kuwatsuka, Tomoka Waseda, Daisuke Ehara, Koji Ando, Hiroyuki Murota   +5 more
wiley   +1 more source

Establishing reference ranges and normal values for coagulation screening in healthy Indian male volunteers enrolled for a longitudinal study

Biomedical and Biotechnology Research Journal, 2019
Background: The study was designed for establishing reference ranges and normal values for coagulation screening in healthy Indian male volunteers.
Rehan Ahmed, Prosenjit Ganguli, Natwar Singh, Surinderpal Singh, Umesh Das Gupta, Yogesh K Jaiswal, Zahid Asharaf, Prasanna Reddy, Velu Nair   +8 more
doaj   +1 more source