Results 111 to 120 of about 32,297 (224)

Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds

Advanced Science, Volume 13, Issue 58, 19 October 2026.
This strategy addresses impaired microcirculation and loss of extracellular matrix (ECM) guidance in diabetic wound healing. Musc@CP, a nanofibrous dressing combining an ECM‐mimetic chitosan‐pullulan scaffold with muscone, enhances perfusion by attenuating intracellular Ca2+ overload‐associated endothelial dysfunction.
Xiang Zheng, Mingmei Li, Jianjun Jiang, Yongchao Wang, Yaru Jia, Weilun Sun, Yi Yao, Pengli Gao, Linhua Zhang, Qi Guo, Guang Jia, Xing‐Jie Liang, Dunwan Zhu, Jinchao Zhang, Fangzhou Li   +14 more
wiley   +1 more source

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

International Forum of Allergy &Rhinology, Volume 16, Issue 10, Page 1094-1106, October 2026.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda, Yohei Sato, Yoshimasa Imoto, Mayumi Tamari, Shigeharu Fujieda   +4 more
wiley   +1 more source

Viscoelastic point-of-care testing for monitoring unfractionated heparin in critically ill patients: a prospective observational study comparing ClotPro® IN/HI-Test, aPTT and Anti-Xa activity

BMC Anesthesiology
Background Monitoring of unfractionated heparin (UFH) in critically ill patients is challenging due to disease-related alterations of the coagulation system, directly affecting conventional laboratory tests, including activated partial thromboplastin ...
Martin Mirus, Anna Dietze, Oliver Tiebel, Jan Beyer-Westendorf, Oliver Grottke, Falko Tesch, Peter Markus Spieth, Lars Heubner   +7 more
doaj   +1 more source

Safety and Feasibility of Magnetic Separation‐Based Blood Purification

Advanced NanoBiomed Research, Volume 6, Issue 10, October 2026.
We present the preclinical biological safety and translational feasibility of a magnetic nanoparticle‐based extracorporeal blood purification platform for removal of disease‐causing blood factors. ISO 10993‐compliant studies and exaggerated worst‐case exposure models demonstrate efficient nanoparticle extraction (≥99.9%), favorable biocompatibility ...
Carlos A. Mora, Laurine Rijsbergen, Jan Waskowski, Gaelle Clermont, Florian Dingreville, Chandrashekara Vishwanath, Rajesh Karunanithi, Alexander Gogos, Jean‐Claude Metzger, Manuel Baumgartner, Joerg C. Schefold, Inge K. Herrmann   +11 more
wiley   +1 more source

Cancer‐Related Microangiopathic Haemolytic Anemia Revealing Occult Metastatic Gastrointestinal Signet‐Ring Cell Carcinoma: A Clinicopathological Case Report and Practical Differential Diagnostic Approach

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT This case highlights key laboratory red flags and a failure to respond to standard treatment, both of which should prompt urgent investigation for occult malignancy in patients presenting with cancer‐related microangiopathic hemolytic anemia (CR‐MAHA).
Danijela Jovanovic, Snezana Sretenovic, Dalibor Jovanovic, Milena Ilic, Predrag Djurdjevic   +4 more
wiley   +1 more source

Hematological Indices Abnormalities Among Sudanese Children With Down Syndrome

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims Down syndrome (DS) is a genetic condition caused by the triplication of chromosome 21. Currently, there is no available published data on hematological parameters among Sudanese children with Down syndrome. Therefore, this study aimed to investigate these parameters among this population.
Manasik Elghali, Abdelhakam G. Tamomh, Rooa Alhaj Ahmed, Tibyan Hassan Abdalmalik, Howida Hajhamd Ibrahim, Ibrahim K. Ibrahim   +5 more
wiley   +1 more source

Clinical Value of Coagulation Function Indicators in Children with Severe Pneumonia

International Journal of General Medicine
Jun Song,1 Ning Li,1 Ruihua Li,1 Yuanyuan Xu2 1Department of Pediatrics, Taihe County People’s Hospital, Fuyang, Anhui, 236000, People’s Republic of China; 2Pediatric Intensive Care Unit, Anhui Children’s Hospital, Hefei, Anhui, 230051, People’s Republic
Song J, Li N, Li R, Xu Y
doaj  

Comparison of Rapid Centrifugation Technique with Conventional Centrifugation for Prothrombin Time (PT) and Activated Partial Thromboplastin Time (APTT) Testing. [PDF]

Indian J Hematol Blood Transfus, 2019
Chandler E, Kakkar N, Kaur R.
europepmc   +1 more source

Time‐ and Temperature‐Dependent Response of Acquired FV Inhibitors: Implications for Laboratory Diagnosis and Clinical Management

Journal of Clinical Laboratory Analysis, Volume 40, Issue 20, October 2026.
This in vitro workflow illustrates the time‐and temperature‐dependent behavior of acquired FV inhibitors. Patient plasma was centrifuged and serially diluted, followed by parallel incubation at room temperature and 37°C. Serial measurements of APTT mixing test and residual FV activity were recorded across incubation time points to monitor inhibitor ...
Lihua Zhang, Mingjie Li, Zhiqiang Xie, Junxiang Yao, Yingping Cao, Lihui Chen, Meihua Wang   +6 more
wiley   +1 more source

Unfractionated Heparin and Low‐Molecular‐Weight Heparin in Sepsis: Anti‐Inflammatory and Anticoagulant Effects Versus No Anticoagulation—A Propensity Score‐Matched Analysis

Journal of Clinical Laboratory Analysis, Volume 40, Issue 20, October 2026.
This propensity score‐matched study compared unfractionated heparin (UFH) and low‐molecular‐weight heparin (LMWH) in 1362 sepsis patients, finding that both significantly improved survival without increasing 90‐day bleeding risk. However, their therapeutic mechanisms differed: UFH demonstrated broader anti‐inflammatory effects by reducing IL‐6, IL‐8 ...
Peili Chen, Yi Yao, Bing Zhao, Yuan An, Jian Jiang, Li Ma, Enqiang Mao, Yihui Wang   +7 more
wiley   +1 more source