Results 211 to 220 of about 688,079 (278)

Activating Transcription Factor 6 Is a Therapeutic Target for Colitis Induced By <i>Citrobacter rodentium</i> Infection in Mice

, 2020
Yunchang Zhang, Da Jiang, Yuhang Jin, Hai Jia, Ying Yang, In Ho Kim, Zhaolai Dai, Jinhua Zhang, Zhenlong Wu   +8 more
openalex   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Advances in the Regulatory Mechanism of Enzymes Involved in Soluble Sugar Metabolism in Fruits. [PDF]

Plants (Basel)
Meng Z, Li W, Huang G, Li X, Li R, Chen Y, Luo S, Guo L, Tang Y, Tang Y, Zhang Y, Ma X, Li L.   +12 more
europepmc   +1 more source

Activation of the inflammatory transcription factor nuclear factor interleukin-6 during inflammatory and psychological stress in the brain [PDF]

, 2013
Franziska Fuchs, Jelena Damm, Rüdiger Gerstberger, Joachim Roth, Christoph Rummel   +4 more
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Practicability of Activating Transcription Factor 3 as a Serological Marker for Severity Appraisal and Outcome Anticipation in Acute Supratentorial Intracerebral Hemorrhage: A Two-center Observational Analytical Study. [PDF]

Brain Behav
Gu Y, Wang X, Xu P, Li Z, Deng X, Cui Y.
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Dual regulation of Atf3 and Lonp1 as therapeutic targets in cerebral ischaemia-reperfusion injury. [PDF]

Stroke Vasc Neurol
Fan W, Zhou M, Zhou L, Tong J, Tan J, Shi W, Yu B.   +6 more
europepmc   +1 more source

Trm1p, a Zn(II) ₂ Cys ₆ -Type Transcription Factor, Is a Master Regulator of Methanol-Specific Gene Activation in the Methylotrophic Yeast Candida boidinii

, 2008
Yu Sasano, Hiroya Yurimoto, Mikiko Yanaka, Yasuyoshi Sakai   +3 more
openalex   +1 more source

Enhanced expression and activation of pro-inflammatory transcription factors distinguish aneurysmal from atherosclerotic aorta: IL-6- and IL-8-dominated inflammatory responses prevail in the human aneurysm [PDF]

, 2008
J. Lindeman, Hazem Abdul-Hussien, Alexander F. Schaapherder, J. Hajo van Bockel, Jan H. von der Thüsen, Dave L. Roelen, Robert Kleemann   +6 more
openalex   +1 more source