Results 291 to 300 of about 638,455 (326)
Advances in the regulation of macrophage polarization by the tumor microenvironment. [PDF]
Discov OncolPeng M, Zhu Y, Hu Y, Wen J, Huang W.
europepmc +1 more source
The Role of Mitochondrial Energy Metabolism in the Mechanism of Exercise Improving Depression. [PDF]
Curr Issues Mol BiolLiu Y +9 more
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Transcriptional Activation of the Factor VIII Gene in Liver Cell Lines by Interleukin-6 [PDF]
Thrombosis and Haemostasis, 1998 SummaryCirculating factor VIII (fVIII) levels increase during inflammation suggesting that fVIII synthesis or secretion is stimulated during acute inflammation. To examine the mechanisms underlying this increase in circulating factor VIII, we have developed a sensitive and reliable semi-quantitative assay for fVIII mRNA utilising competitive reverse ...
David Stirling +2 more
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Nature Genetics, 2006
The molecular basis of nephronophthisis, the most frequent genetic cause of renal failure in children and young adults, and its association with retinal degeneration and cerebellar vermis aplasia in Joubert syndrome are poorly understood. Using positional cloning, we here identify mutations in the gene CEP290 as causing nephronophthisis.
Daniel Goldman +42 more
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The molecular basis of nephronophthisis, the most frequent genetic cause of renal failure in children and young adults, and its association with retinal degeneration and cerebellar vermis aplasia in Joubert syndrome are poorly understood. Using positional cloning, we here identify mutations in the gene CEP290 as causing nephronophthisis.
Daniel Goldman +42 more
openaire +4 more sources
Transcription factor GATA-6 activates expression of gastroprotective trefoil genes TFF1 and TFF2
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 2000One of the early events in inflammation and epithelial restitution of the gastrointestinal tract is the up-regulation of secretory peptides belonging to the trefoil factor family (TFF) that promote cell migration, protect and heal the mucosa. Their major expression site is stomach (TFF1, TFF2) and intestine (TFF3).
Petra Fegert +3 more
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Transcription Factor GATA-6 Recruits PPARα to Cooperatively Activate Glut4 Gene Expression
Journal of Molecular Biology, 2012Peroxisome proliferator-activated receptor α (PPARα) is a nuclear hormone receptor that regulates energy metabolism, but its precise mechanisms remain unknown. Here, we demonstrate that the PPARα agonist fenofibrate activated expression of the glucose transporter Glut4.
Cheng-Juan Xiong +9 more
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