Results 91 to 100 of about 6,391,825 (297)

Moss Biomonitoring in the Evaluation of Air Pollution in the Tver Region, Russia

Atmosphere
In the Tver region (Russia), the moss biomonitoring technique was applied to investigate the atmospheric deposition of potentially harmful elements. Using inductively coupled plasma–optical emission spectroscopy and a direct mercury analyzer, a total of ...
Konstantin Vergel, Inga Zinicovscaia, Nikita Yushin, Omari Chaligava, Liliana Cepoi, Alexandra Kravtsova   +5 more
doaj   +1 more source

Dissecting Distinct Roles of NEDDylation E1 Ligase Heterodimer APPBP1 and UBA3 Reveals Potential Evolution Process for Activation of Ubiquitin-related Pathways. [PDF]

, 2018
Despite the similar enzyme cascade in the Ubiquitin and Ubiquitin-like peptide(Ubl) conjugation, the involvement of single or heterodimer E1 activating enzyme has been a mystery.
Gaieb, Zied, Kung, Raphael, Le, Frank, Liao, Jiayu, Malik-Chaudhry, Harbani Kaur, Morikis, Dimitrios, Reyes, Michael, Saavedra, Amanda   +7 more
core  

On the Importance of Normalisation Layers in Deep Learning with Piecewise Linear Activation Units

, 2015
Deep feedforward neural networks with piecewise linear activations are currently producing the state-of-the-art results in several public datasets.
Carneiro, Gustavo, Liao, Zhibin
core   +1 more source

Identifying Activity

SIAM Journal on Optimization, 2011
Identification of active constraints in constrained optimization is of interest from both practical and theoretical viewpoints, as it holds the promise of reducing an inequality-constrained problem to an equality-constrained problem, in a neighborhood of a solution. We study this issue in the more general setting of composite nonsmooth minimization, in
Adrian S. Lewis, Stephen J. Wright 0001
openaire   +3 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Notch2 controls developmental fate choices between germinal center and marginal zone B cells upon immunization

Nature Communications
Sustained Notch2 signals induce trans-differentiation of Follicular B (FoB) cells into Marginal Zone B (MZB) cells in mice, but the physiology underlying this differentiation pathway is still elusive.
Tea Babushku, Markus Lechner, Stefanie Ehrenberg, Ursula Rambold, Marc Schmidt-Supprian, Andrew J. Yates, Sanket Rane, Ursula Zimber-Strobl, Lothar J. Strobl   +8 more
doaj   +1 more source

PD-1 Blockade Promotes Emerging Checkpoint Inhibitors in Enhancing T Cell Responses to Allogeneic Dendritic Cells

Frontiers in Immunology, 2017
Immune checkpoint inhibitors, which target coinhibitory T cell molecules to promote anticancer immune responses, are on the rise to become a new pillar of cancer therapy.
Carmen Stecher, Claire Battin, Judith Leitner, Markus Zettl, Katharina Grabmeier-Pfistershammer, Christoph Höller, Gerhard J. Zlabinger, Peter Steinberger   +7 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Catalytic Hydrogenation of Polyurethanes to Base Chemicals: From Model Systems to Commercial and End-of-Life Polyurethane Materials

JACS Au, 2021
Laurynas Gausas, Steffan K. Kristensen, Hongwei Sun, Alexander Ahrens, Bjarke S. Donslund, Anders T. Lindhardt, Troels Skrydstrup   +6 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source