Results 121 to 130 of about 7,192,603 (344)

Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation

, 2016
Max A. Horlbeck, Luke A. Gilbert, Jacqueline E. Villalta, Britt Adamson, Ryan A. Pak, Yuwen Chen, Alexander P. Fields, Chong Yon Park, Jacob E. Corn, Martin Kampmann, Jonathan S. Weissman   +10 more
openalex   +1 more source

Correspondence of the brain's functional architecture during activation and rest

Proceedings of the National Academy of Sciences of the United States of America, 2009
Stephen M. Smith, P. Fox, K. Miller, D. Glahn, P. Fox, C. Mackay, N. Filippini, K. Watkins, R. Toro, A. Laird, C. Beckmann, C. Beckmann   +11 more
semanticscholar   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

RETRACTED: Long Noncoding RNA LINC00673 Is Activated by SP1 and Exerts Oncogenic Properties by Interacting with LSD1 and EZH2 in Gastric Cancer [PDF]

, 2017
Mingde Huang, Jiakai Hou, Yunfei Wang, Min Xie, Chenchen Wei, Fengqi Nie, Zhaoxia Wang, Ming Sun   +7 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Syntrophin mutation associated with long QT syndrome through activation of the nNOS–SCN5A macromolecular complex

, 2008
Kazuo Ueda, Carmen R. Valdivia, Argelia Medeiros‐Domingo, David J. Tester, Matteo Vatta, Gianrico Farrugia, Michael J. Ackerman, Jonathan C. Makielski   +7 more
openalex   +1 more source

THE THROMBOTIC ACTIVITY OF ACTIVATION PRODUCT* [PDF]

Journal of Clinical Investigation, 1962
E S, HENDERSON, S L, RAPAPORT
openaire   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Receptor for advanced glycation end products (AGEs) has a central role in vessel wall interactions and gene activation in response to circulating AGE proteins.

, 1994
Ann Marie Schmidt, M. Hasu, Doina Popov, J H Zhang, Jia Chen, Shi Du Yan, J Brett, Rong Cao, Kosuke Kuwabara, G Costache   +9 more
openalex   +2 more sources

Slack, Slick, and Sodium-Activated Potassium Channels [PDF]

, 2013
Leonard K. Kaczmarek
openalex   +1 more source