Results 71 to 80 of about 885,150 (312)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Activation Optimization and Congestion Management in the European Balancing Energy Market

, 2019
At the heart of the electricity system, a System Operator (referred to as Transmission System Operator (TSO) in Europe) faces the crucial task of coordinating the continuous balance between generation and consumption.
Håberg, Martin
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Thermodynamic properties and drying kinetics of ‘okara’

Revista Brasileira de Engenharia Agrícola e Ambiental
‘Okara’ is the insoluble part obtained after the aqueous extraction of soybeans, generated in large quantities as a by-product of the ‘tofu’ industry or soybean water-soluble extract. This work aimed to study ‘okara’ convective drying kinetics, determine
Rafaiane M. Guimarães, Daniel E. C. de Oliveira, Osvaldo Resende, Jhessika de S. Silva, Thaisa A. M. de Rezende, Mariana B. Egea   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Energy Homeostasis, Autonomic Activity and Obesity [PDF]

Obesity Research, 1995
Obesity is often accompanied by alterations in both sympathetic and parasympathetic autonomic functions. The present paper summarizes the results of a number of studies designed to investigate autonomic functioning in normal, genetically, and experimentally obese rats. Particular emphasis is given to autonomic functioning and dysfunctioning in relation
Scheurink, AJW, Balkan, B, Nyakas, C, vanDijk, G, Steffens, AB, Bohus, B   +5 more
openaire   +3 more sources

KINETIC CHARACTERIZATION OF DIFFERENT PHENYTOIN POLYMORPHS BY DSC TECHNIQUE

Vitae, 2009
The activation energy variation can be used as a quick measure to differentiate polymorphs of active pharmaceutical ingredients. In this paper diverse phenytoin crystal habits have been obtained through processes of recrystallization in different ...
Oscar A. FLOREZ A., Gloria E. TOBÓN Z., Erika M. LOPERA G.   +2 more
doaj  

Impedance spectroscopy and electrical conductivity of 0.7BiNdxFeO3–0.3BaTiO3 ferroelectric ceramics

Journal of Advanced Dielectrics
0.7Bi[Formula: see text]NdxFeO3–0.3BaTiO3 (BNFO–BTO, [Formula: see text], 0.010, 0.020 and 0.050) ceramics were fabricated using the high-temperature solid-state reaction method.
Hui Tang, Xiao-Cao Peng, Jiu-Ming Ma, Zhi-Peng Yang, Xiang Niu, Jun-Xia Wen, Xin-Gui Tang, Sheng-Guo Lu   +7 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source