Results 81 to 90 of about 7,619,054 (294)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Zero energy homes: Combining energy efficiency and solar energy technologies

, 2000
In a typical Florida house, air-conditioning accounts for about 35% of all the electricity the home uses. As the largest single source of energy consumption in Florida, a home's air-conditioning load represents the biggest energy challenge facing Florida
National Renewable Energy Laboratory (U.S.)
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Reliability and Life Research of Certain Autonomous Emergency Solenoid Valve

Chengshi guidao jiaotong yanjiu
[Objective] To achieve the autonomous control and safe application of emergency solenoid valves, a reliability and accelerated life test research on autonomous emergency solenoid valves is carried out. The existing design is improved through test results
DU Zhanjiang, TAO Fuwen
doaj   +1 more source

Effect of the solvent type and polymerization conditions on the curing kinetics, thermal and viscoelastic performance of poly(amide-imide) resins

eXPRESS Polymer Letters, 2015
Isothermal and non-isothermal curing kinetics of both N-methyl-2-pyrrolidone (NMP) and N-methylimidazole (MI) based poly(amide-imide) (PAI) resins were investigated by DSC analysis using tightly closed high-pressure crucibles. Several exothermal peaks on
Z. Rasheva, L. Sorochynska, S. Grishchuk, K. Friedrich   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Investigation of the Thermal Degradation Behavior of Coal/Biomass Blends for Kinetics Analysis with Sequential Method Implication

Architecture, Civil Engineering, Environment
Pakistan currently has a problem in the energy supply and demand. There is a large gap between supply and demand for electricity. The depletion of fossil fuels and environmental pollution factors also exist.
SHOAIB Hafiz Muhammad, QURESHI Tayyab, KHAN Ihtisham, MAHMOOD Hamayoun, IQBAL Tanveer   +4 more
doaj   +1 more source

Solid Polymer Electrolytes Based on Chitosan:NH4Tf Modified by Various Amounts of TiO2 Filler and its Electrical and Dielectric Characteristics

International Journal of Electrochemical Science, 2019
In the current work the role of titanium dioxide (TiO2) filler on dielectric and conductivity properties of chitosan (CS) based solid polymer electrolytes (SPEs) were investigated at various temperatures. To prepare CS based SPEs fixed amount of ammonium
Shujahadeen B. Aziz, Omed G.H. Abdullah, Shakahawan Al-zangana   +2 more
doaj   +1 more source