Results 21 to 30 of about 563 (208)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Il posto del lavoro nella sicurezza sociale [PDF]

Culture e Studi del Sociale, 2016
The Italian labour market is crossed in various ways by flows of polarization produced by neoliberal policies and the new economy of ICT. Main victims are women, young people, immigrants, especially those labour forces residing in the South.
Sandro Turcio
doaj   +1 more source

Is there a Role for an Active Fiscal Stabilization Policy? [PDF]

CESifo Economic Studies, 2005
This paper discusses the need and scope for an active fiscal stabilization policy. It is argued that the effectiveness of fiscal policy as a short run stabilizer does not depend on the long run multipliers of (balanced budget) fiscal policies. To the extent that activity can be affected by aggregate demand in the short run, there is a case for a fiscal
openaire   +3 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Evaluation of the transversal actions of the New Deal: operational partnerships to promote employment for the Brussels residents?

Brussels Studies, 2015
In 2011, social partners and the Brussels government signed the New Deal, aimed at reinforcing the coherence of the Brussels employment policy through partnerships between the stakeholders concerned, both private and public. The evaluation of this public
Sabrine Cipriano, Catherine Fallon, Perrine Fastré, Jordan Halin   +3 more
doaj   +1 more source

‘Double activation’: Workfare meets marketisation

Administration, 2021
Since the financial crisis, Ireland’s welfare state has been reorientated around a regulatory, ‘work-first’ activation model. Claimants now face penalty rates for non-compliance with activation requirements that have been significantly extended since ...
McGann Michael
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

The transition of young people from education to employment in Brussels: challenges for governance

Brussels Studies, 2014
The dualisation of the education system, early school leaving, the high unemployment rate of low-skilled young people and chronic insecurity underline the difficulties involved in the transition of low-skilled young people from education to employment ...
Abraham Franssen, Donat Carlier, Anissa Benchekroun   +2 more
doaj   +1 more source

Keyword Analysis of Artificial Intelligence Education Policy in South Korea

IEEE Access, 2023
The purpose of this study is to analyze the direction of the Artificial Intelligence (AI) education policy announced by the South Korean government and how key tasks are reflected in detailed policies to find implications.
Jaeho Lee, Hongwon Jeong
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source