Results 1 to 10 of about 5,159,031 (214)

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

open access: yesCell Research, 2013
Technologies allowing for specific regulation of endogenous genes are valuable for the study of gene functions and have great potential in therapeutics.
Albert W Cheng   +2 more
exaly   +2 more sources

Luminescence of Cr-doped β-Ga2O3 thin films

open access: yesФізика і хімія твердого тіла, 2023
The results of investigation of optical excitation, photoluminescence (PL) and cathodoluminescence (CL) spectra in Cr-doped β-Ga2O3 thin films are presented. The broad bands due to the generation of electron-hole pairs and transitions from the 4А2 ground
O.M. Bordun   +4 more
doaj   +1 more source

Alkyl derivative of p-terphenyl as an activator of polysiloxane-based scintillator [PDF]

open access: yesЯдерна фізика та енергетика, 2022
One of the problems in creating a radiation-hard scintillation composition on a polysiloxane base is the search for a radiation-hard activator capable of dissolving in such a base in sufficient quantity.
P. М. Zhmurin   +4 more
doaj   +1 more source

Human Sirtuin Regulators: The “Success” Stories

open access: yesFrontiers in Physiology, 2021
The human sirtuins are a group of NAD+-dependent protein deacylases. They “erase” acyl modifications from lysine residues in various cellular targets including histones, transcription factors, and metabolic enzymes. Through these far-reaching activities,
Alyson M. Curry   +4 more
doaj   +1 more source

Effect of Sodium Hydroxide, Liquid Sodium Silicate, Calcium Hydroxide, and Slag on the Mechanical Properties and Mineral Crystal Structure Evolution of Polymer Materials

open access: yesCrystals, 2021
To study the key factors that affect the mechanical properties of polymer materials and explore the relationship between mineral crystal formation and strength development, fly ash (FA) polymer samples were prepared using sodium hydroxide, slag, liquid ...
Guodong Huang   +5 more
doaj   +1 more source

The Plasminogen–Activator Plasmin System in Physiological and Pathophysiological Angiogenesis

open access: yesInternational Journal of Molecular Sciences, 2021
Angiogenesis is a process associated with the migration and proliferation of endothelial cells (EC) to form new blood vessels. It is involved in various physiological and pathophysiological conditions and is controlled by a wide range of proangiogenic ...
A. Ismail, B. Shaker, K. Bajou
semanticscholar   +1 more source

Activators and Inhibitors of Protein Kinase C (PKC): Their Applications in Clinical Trials

open access: yesPharmaceutics, 2021
Protein kinase C (PKC), a family of phospholipid-dependent serine/threonine kinase, is classed into three subfamilies based on their structural and activation characteristics: conventional or classic PKC isozymes (cPKCs; α, βI, βII, and γ), novel or non ...
Takahito Kawano   +4 more
doaj   +1 more source

Alkyl derivative of p-terphenyl as an activator of the plastic scintillators with n/γ-discrimination ability [PDF]

open access: yesЯдерна фізика та енергетика, 2023
In order to increase the solubility of p-terphenyl molecules, their structure was modified with tert-butyl groups. A derivative of p-terphenyl 2,4,4′-tris-tert-butyl-1,1′:4′,1′-terphenyl was obtained.
D. A. Yelisieiev   +4 more
doaj   +1 more source

Management of hardening mixtures properties when stowing mining sites of ore deposits

open access: yesЗаписки Горного института, 2020
Underground mining is characterized by the weakening of the bearing rock mass strata competence and the accumulation of mineral waste. The full use of subsurface resources is ensured by the use of technologies with filling voids by hardening mixtures ...
Vladimir I. Golik   +3 more
doaj   +1 more source

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