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Transcriptional activators and activation mechanisms [PDF]
Protein & Cell, 2007 Transcriptional activators are required to turn on the expression of genes in a eukaryotic cell. Activators bound to the enhancer can facilitate either the recruitment of RNA polymerase II to the promoter or its elongation. This article examines a few selected issues in understanding activator functions and activation mechanisms.
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Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade [PDF]
, 2012 Gelsolin is a cytoskeletal protein which participates in actin filament dynamics and promotes cell motility and plasticity. Although initially regarded as a tumor suppressor, gelsolin expression in certain tumors correlates with poor prognosis and ...
Prem Kumar +83 more
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Frontiers in Oncology, 2018 The plasminogen activator (PA) system is an extracellular proteolytic enzyme system associated with various physiological and pathophysiological processes.
Niaz Mahmood, C. Mihalcioiu, S. Rabbani
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Preparation and Oxidation Resistance of Mo-Si-B Coating on Nb-Si Based Alloy Surface
Cailiao gongcheng, 2018 Mo-Si-B coating was prepared on Nb-Si alloys to improve the high-temperature oxidation. The influence of the halide activators (NaF and AlF3) on Si-B co-depositing to obtain Mo-Si-B coating on Nb-Si alloys was analyzed by thermochemical calculations. The
PANG Jie, ZHOU Chun-gen
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ChemElectroChem, 2022 In this work, we systematically investigate the ‘catalytic’ graphitization of a biomass precursor (coffee ground) using 10–60 wt. % of the activator iron (III) chloride hexahydrate in a temperature range of 1000 °C – 2400 °C.
Vanessa Hanhart +6 more
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Alkyl derivative of p-terphenyl as an activator of polysiloxane-based scintillator [PDF]
Ядерна фізика та енергетика, 2022 One of the problems in creating a radiation-hard scintillation composition on a polysiloxane base is the search for a radiation-hard activator capable of dissolving in such a base in sufficient quantity.
P. М. Zhmurin +4 more
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Active voice, active writing [PDF]
Ubiquity, 2020 Each "Communication Corner" essay is self-contained; however, they build on each other. For best results, before reading this essay and doing the exercise, go to the first essay "How an Ugly Duckling Became a Swan," then read each succeeding essay. Knowing when to write in the active or passive voice can fundamentally improve your work, but ...
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2017 Identifying possible new biological activities of psychoactive substances belonging to various chemical classes may lead to a better understanding of their mode of action and side effects. We report here that amines structurally related to amphetamine, a
Andrea Angeli +4 more
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Activation of β- and γ-carbonic anhydrases from pathogenic bacteria with tripeptides
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 Six tripeptides incorporating acidic amino acid residues were prepared for investigation as activators of β- and γ-carbonic anhydrases (CAs, EC 4.2.1.1) from the pathogenic bacteria Vibrio cholerae, Mycobacterium tuberculosis, and Burkholderia ...
Azzurra Stefanucci +8 more
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Human Sirtuin Regulators: The “Success” Stories
Frontiers in Physiology, 2021 The human sirtuins are a group of NAD+-dependent protein deacylases. They “erase” acyl modifications from lysine residues in various cellular targets including histones, transcription factors, and metabolic enzymes. Through these far-reaching activities,
Alyson M. Curry +4 more
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