Results 241 to 250 of about 4,610,135 (394)

Host genetic variation and gut microbiome in pediatric diseases. [PDF]

Chin Med J (Engl)
Meng Y, Wang H, Mu D, Zeng S, Wang S.
europepmc   +1 more source

An Update on Post-infectious Irritable Bowel Syndrome: Role of Genetics, Immune Activation, Serotonin and Altered Microbiome

, 2012
Robert E. Spiller, Ching Lam
openalex   +2 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Targeted disruption of the mouse sphingolipid activator protein gene: a complex phenotype, including severe leukodystrophy and wide-spread storage of multiple sphingolipids.

Human Molecular Genetics, 1996
N. Fujita, Kinuko Suzuki, Marie T. Vanier, Brian Popko, Nobuyo Maeda, Andreas Klein, M. Henseler, Konrad Sandhoff, Hiroyuki Nakayasu, Kunihiko Suzuki   +9 more
semanticscholar   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Author Correction: The kinase TNIK is an essential activator of Wnt target genes. [PDF]

EMBO J
Mahmoudi T, Li VSW, Ng SS, Taouatas N, Vries RGJ, Mohammed S, Heck AJ, Clevers H.   +7 more
europepmc   +1 more source

Epileptic and developmental disorders of the speech cortex: ligand/receptor interaction of wild-type and mutant SRPX2 with the plasminogen activator receptor uPAR.

Human Molecular Genetics, 2008
Barbara Royer-Zemmour, Magali Ponsole-Lenfant, Hyam Gara, P. Roll, C. Lévêque, A. Massacrier, G. Ferracci, J. Cillario, A. Robaglia-Schlupp, R. Vincentelli, P. Cau, P. Szepetowski   +11 more
semanticscholar   +1 more source

Genetics of common variable immunodeficiency: role of transmembrane activator and calcium modulator and cyclophilin ligand interactor [PDF]

, 2015
Harindra D. Sathkumara, N. R. De Silva, Shiroma M. Handunnetti, Aruna Dharshan De Silva   +3 more
openalex   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source