Results 221 to 230 of about 4,610,135 (394)

PlantReg 1.1 identifies the mutual arrangement of transcription factor binding sites in the target promoters for the elucidation of molecular mechanisms within regulatory networks. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Lavrekha VV, Omelyanchuk NA, Bogomolov AG, Ryabov YA, Mukebenova PK, Zemlyanskaya EV.   +5 more
europepmc   +1 more source

The signal transducer and activator of transcription STAT5b gene is a new partner of retinoic acid receptor alpha in acute promyelocytic-like leukaemia.

Human Molecular Genetics, 1999
C. Arnould, C. Philippe, V. Bourdon, M. Grégoire, R. Berger, P. Jonveaux   +5 more
semanticscholar   +1 more source

Hyperpolarization-activated cyclic nucleotide-gated channels and epilepsy: genetics, circuits, and treatments [PDF]

Ming-Shan Cai, Peng Liao, Zhenliang Hu, Yun Li, Jiaxing Zhao, Liang Jin, Hong-Wei Wang, Yong-Jun Chen   +7 more
openalex   +1 more source

Peroxisome Proliferator-Activated Receptor-γ Calls for Activation in Moderation: Lessons from Genetics and Pharmacology [PDF]

, 2004
Chris Knouff, Johan Auwerx
openalex   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Molecular Mechanisms of Transcription Factors with Dual Activator and Repressor Functions. [PDF]

Mol Cell Biol
Dong J, Guertin MJ.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Genetic evidence informs the direction of therapeutic modulation in drug development. [PDF]

NPJ Drug Discov
Chen R, Duffy Á, Park JK, Stein D, Schlessinger A, Itan Y, Glicksberg BS, Tinker RJ, Jordan DM, Rocheleau G, Do R.   +10 more
europepmc   +1 more source

Community Analysis of Ammonia Oxidizing Bacteria through Molecular Genetics in Activated Sludge of Effluent Treatment Plant

, 2015
Maulin P. Shah, Chongxuan Liu, Nitin Gawande, Jmbt, M Shah, M Shah, M Shah, K Patel, S Siripong, B Rittmann, G Wells, H Park, C Yeung, B Eggleston, C Francis, H Satoh, T Yamakawa, T Kindaichi, T Ito, S Okabe, X Wang, X Wen, C Criddle, G Wells, J Zhang, J Lim, H Do, S Shin, S Hwang, K Gilbride, D Lee, L Beaudette, B Zhang, B Sun, M Ji, H Liu, X Liu, T Limpiyakorn, F Kurisu, Y Sakamoto, O Yagi, M Dytczak, K Londry, J Oleszkiewicz, A Akarsubasi, O Eyice, I Miskin, I Head, T Curtis, M Pholchan, Baptista Jde, C Davenport, R Curtis, T, L Wittebolle, H Vervaeren, W Verstraete, N Boon, A Briones, L Raskin, J Stephen, A Mccaig, Z Smith, J Prosser, T Embley, G Kowalchuk, J Stephen, De Boer, W Prosser, J Embley, T, U Edwards, T Rogall, H Blcker, M Emde, E Bttger, V Sheffield, D Cox, L Lerman, R Myers, G Muyzer, S Hottentrager, A Teske, C Wawer, J Stephen, G Kowalchuk, Mav Bruns, A Mccaig, C Phillips, T Jukes, C Cantor, N Saitou, M Nei, W Pearson, D Lipman, P Bodelier, J Libochant, C Blom, H Laanbroek, V Degrange   +99 more
openalex   +1 more source