Results 211 to 220 of about 4,610,135 (394)

Intersection of population variation and autoimmunity genetics in human T cell activation

, 2014
C. J. Ye, Ting Feng, Ho‐Keun Kwon, Towfique Raj, Michael T. Wilson, Natasha Asinovski, Cristin McCabe, M. H. Lee, I. Fröhlich, Hyun-il Paik, Noah Zaitlen, Nir Hacohen, Barbara E. Stranger, Philip L. De Jager, Diane Mathis, Christophe Benoıst, Aviv Regev   +16 more
openalex   +4 more sources

Distinct mechanisms decommission redundant enhancers to facilitate phenotypic evolution. [PDF]

Sci Adv
Said-Ahmad A, Shimron N, Samach EF, Naik S, Roy S, Frankel N, Noon EP.   +6 more
europepmc   +1 more source

Genetics: Promoting Gene Activity [PDF]

Nature, 1972
openaire   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Influence of Hemostatic Disorder on Type II Endoleak Development After Endovascular Abdominal Aortic Aneurysm Repair. [PDF]

Int J Mol Sci
Rynio P, Kłysz M, Samad R, Bieniek M, Lisman D, Rybicka A, Skórka P, Lempek P, Cnotliwy M, Kazimierczak A, Gutowski P, Jastrzębska M, Siennicka A.   +12 more
europepmc   +1 more source

The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis.

Human Molecular Genetics, 2005
Jin Xu, N. Zhong, Haoyong Wang, Joshua E. Elias, Christina Y Kim, I. Woldman, C. Pifl, S. Gygi, C. Geula, B. Yankner   +9 more
semanticscholar   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Enhanced SfaTnpB enables single-base-specific, one-pot nucleic acid detection for high-sensitivity diagnostics. [PDF]

Nucleic Acids Res
Xu B, Li S, Li Y, Zhao S, Li X, Han J, Wu D, Li S, Chen L, Xie S, Han X, Zhao C.   +11 more
europepmc   +1 more source

Epistatic Interactions between Opaque2 Transcriptional Activator and Its Target Gene CyPPDK1 Control Kernel Trait Variation in Maize1[C][W][OA]

Plant Physiology, 2009
D. Manicacci, L. Camus-Kulandaivelu, M. Fourmann, C. Arar, S. Barrault, A. Rousselet, Noël Feminias, L. Consoli, Lisa Francès, V. Méchin, A. Murigneux, J. Prioul, A. Charcosset, C. Damerval   +13 more
semanticscholar   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source