Results 341 to 350 of about 3,963,692 (395)
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Genetic activity profiles of anticancer drugs
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1996The results from short-term tests for genetic and related effects, abstracted from the open literature for 36 anticancer drugs, are examined in this review. Data for 27 of these agents are available in the EPA/IARC Genetic Activity Profile (GAP) database.
M A, Jackson, H F, Stack, M D, Waters
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Genetics and activity inDrosophila melanogaster
Experientia, 1967Eine Methode zur Abschatzung dreier Masstabe von Lokomotionsaktivitat beiDrosophila melanogaster, die unter gemeinsamer genetischer Kontrolle stehen, wird beschrieben. Es wird wahrscheinlich gemacht, dass die Kontrolle des einem Masstrbes von einem besonderen Teil des Gen-Komplementes ausgeubt wird, wahrend die andern mehrere kontrollierende Gene ...
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Paraoxonase 1: Genetics and Activities During Aging
Rejuvenation Research, 2008The increasing longevity of the population, one of the most important issues throughout the planet, is a very complex phenomenon (trait), likely resulting from a variety of environmental determinants interacting with and modulated by genetic mechanisms, mostly devoted to maintenance and repair. In fact, the genes involved in longevity impact upon basic
Marchegiani F. +6 more
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Genetic determinants of autoimmune chronic active hepatitis
Springer Seminars in Immunopathology, 1980There has been a remarkable vindication over the past 15 years of Burnet’s forecast, with two particular themes of dominant interest to research on immunogenetics. The first is the association in inbred animals between genetic control of immune responses to antigens of limited heterogeneity and genes (Ir genes) of the major histocompatibility complex ...
I R, Mackay +3 more
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Genetic activity of niridazole in yeast
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1975Niridazole, one of several drugs presently known to be of value in the treatment of human schistosomiasis, was tested for its activity in inducing mitotic recombination in yeast. It was found that niridazole is genetically active when the treatment of yeast cells is performed in a rich medium (YPG-medium) under growing conditions, but not when ...
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Genetic and Non-Genetic Determinants of the Pharmacological Activity of Statins
Current Drug Metabolism, 2016Statins are cholesterol-lowering agents which belong to the group of the most commonly prescribed drugs. The use of statins has become the standard treatment in patients with an increased risk of cardiovascular and coronary heart diseases. However, many clinical studies have shown that 13 - 75% of patients fail to achieve LDL-cholesterol and total ...
Marta, Karazniewicz-Lada +3 more
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Ultrastructural Aspects of Genetic Activity
1973Electron microscopic analysis of the material released by gentle lysis of prokaryotic and eukaryotic cells has provided information on the in vivo structure of transcription complexes. We have identified active nonribosomal and ribosomal RNA genes in both cell types (for reviews see Miller and Hamkalo, 1972; Hamkalo and Miller, 1973).
Barbara A. Hamkalo +2 more
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Vitiligo Treatments: Review of Current Therapeutic Modalities and JAK Inhibitors
American Journal of Clinical Dermatology, 2023Kaitlynne N. Cunningham, D. Rosmarin
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{BLR 877}Plasminogen Activator - Genetics Institute - Licensing
, 1989semanticscholar +1 more source
Genetic activity and fragile sites
Cancer Genetics and Cytogenetics, 1991F, Hecht, B K, Hecht
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