Results 341 to 350 of about 4,610,135 (394)

Genetic determinants of autoimmune chronic active hepatitis

Springer Seminars in Immunopathology, 1980
There has been a remarkable vindication over the past 15 years of Burnet’s forecast, with two particular themes of dominant interest to research on immunogenetics. The first is the association in inbred animals between genetic control of immune responses to antigens of limited heterogeneity and genes (Ir genes) of the major histocompatibility complex ...
I R, Mackay, S, Whittingham, J D, Mathews, B D, Tait   +3 more
openaire   +2 more sources

Genetic activity of niridazole in yeast

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1975
Niridazole, one of several drugs presently known to be of value in the treatment of human schistosomiasis, was tested for its activity in inducing mitotic recombination in yeast. It was found that niridazole is genetically active when the treatment of yeast cells is performed in a rich medium (YPG-medium) under growing conditions, but not when ...
openaire   +2 more sources

Genetic and Non-Genetic Determinants of the Pharmacological Activity of Statins

Current Drug Metabolism, 2016
Statins are cholesterol-lowering agents which belong to the group of the most commonly prescribed drugs. The use of statins has become the standard treatment in patients with an increased risk of cardiovascular and coronary heart diseases. However, many clinical studies have shown that 13 - 75% of patients fail to achieve LDL-cholesterol and total ...
Marta, Karazniewicz-Lada, Anna, Glowka, Jakub, Mikolajewski, Juliusz, Przyslawski   +3 more
openaire   +2 more sources

Ultrastructural Aspects of Genetic Activity

1973
Electron microscopic analysis of the material released by gentle lysis of prokaryotic and eukaryotic cells has provided information on the in vivo structure of transcription complexes. We have identified active nonribosomal and ribosomal RNA genes in both cell types (for reviews see Miller and Hamkalo, 1972; Hamkalo and Miller, 1973).
Barbara A. Hamkalo, O. L. Miller, Aimée H. Bakken   +2 more
openaire   +1 more source

The contribution of different adipose tissue depots to plasma plasminogen activator inhibitor-1 (PAI-1) levels.

Blood reviews, 2016
S. Barnard, M. Pieters, Zelda de Lange
semanticscholar   +1 more source

{BLR 877}Plasminogen Activator - Genetics Institute - Licensing

, 1989

semanticscholar   +1 more source

Genetic activity and fragile sites

Cancer Genetics and Cytogenetics, 1991
F, Hecht, B K, Hecht
openaire   +2 more sources

Verticillium transcription activator of adhesion Vta2 suppresses microsclerotia formation and is required for systemic infection of plant roots.

New Phytologist, 2014
Van-Tuan Tran, S. Braus-Stromeyer, H. Kusch, Michael Reusche, A. Kaever, Anika Kühn, O. Valerius, Manuel Landesfeind, K. Aßhauer, M. Tech, Katharina Hoff, T. Peña-Centeno, M. Stanke, Volker Lipka, G. Braus   +14 more
semanticscholar   +1 more source

Genetical Aspects of Active Defence

1982
I find myself in a rather uncomfortable position in presenting this paper. The reason for this is that what I have to say does not support much of the speculation and dogma that has been presented in preceding papers. I feel like a non-believer in a congregation of believers.
openaire   +1 more source

Targeted genetic prodrug activation therapy

2003
Abstract Genetically modifying a cell so that it gains sensitivity to a particular agent resulting in cell death is an attractive anticancer strategy, especially if the therapy is able to distinguish between tumor and normal tissues.
openaire   +1 more source