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Novel insights into the complex architecture of osteoporosis molecular genetics

Annals of the New York Academy of Sciences, 2020
Osteoporosis is a prevalent osteodegenerative disease and silent killer linked to a decrease in bone mass and decline of bone microarchitecture, due to impaired bone matrix mineralization, raising the risk of fracture.
F. Saad
semanticscholar   +1 more source

Electronmicroscopy of Genetic Activity

Annual Review of Biochemistry, 1973
ACTIVE GENES FROM AMPHIBIAN OOCYTES 379 Ribosomal RNA genes 380 Lampbrush chromosomes 383 ACTtVZ GeNeS FROM BACteRiA 384 Structural genes 384 Ribosomal RNA genes 388 Bacteriophage genetic activity 390 YEAST GENETIC ACTiViTY 392 MAMMALIAN GE ETIC ACTIVITY ...
O L Miller, B A Hamkalo
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The Genetics of Physical Activity

Current Cardiology Reports, 2017
Physical activity (PA) is a well-established modifiable lifestyle determinant for multiple cardio-metabolic outcomes. While many psychosocial and environmental correlates of PA have been identified, current understanding of the genetic architecture that contributes to PA is still very limited, especially when compared to other phenotypes such as ...
Simin Liu   +5 more
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Genetic prodrug activation therapy

The Lancet, 1997
Genetic prodrug activation therapy shows promise as a therapeutic option for the treatment of cancer as well as a variety of other diseases. It involves the insertion of a gene encoding a drug-metabolizing enzyme into cells and the systemic administration of a prodrug. The prodrug is converted to a cytotoxic agent by the action of the expressed enzyme.
H. S. Pandha   +4 more
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The genetics of macrophage activation syndrome

Genes & Immunity, 2020
Macrophage activation syndrome (MAS), or secondary hemophagocytic lymphohistiocytosis (HLH), is a cytokine storm syndrome associated with multi-organ system dysfunction and high mortality rates. Laboratory and clinical features resemble primary HLH, which arises in infancy (1 in 50,000 live births) from homozygous mutations in various genes critical to
Randy Q. Cron, Grant S. Schulert
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Genetic activity of allyl chloride

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1978
Allyl chloride (3-chloroprene) is mutagenic for Salmonella typhimurium and it induces gene conversions in Saccharomyces cerevisiae. It also displays DNA-modifying activity for E. coli. This is in contrast to a recent study which reported its lack of genetic activity for Salmonella typhimurium.
Herbert S. Rosenkranz   +2 more
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Verticillium transcription activator of adhesion Vta2 suppresses microsclerotia formation and is required for systemic infection of plant roots.

New Phytologist, 2014
Six transcription regulatory genes of the Verticillium plant pathogen, which reprogrammed nonadherent budding yeasts for adhesion, were isolated by a genetic screen to identify control elements for early plant infection.
Van-Tuan Tran   +14 more
semanticscholar   +1 more source

Genetic activity of niridazole in yeast

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1975
Niridazole, one of several drugs presently known to be of value in the treatment of human schistosomiasis, was tested for its activity in inducing mitotic recombination in yeast. It was found that niridazole is genetically active when the treatment of yeast cells is performed in a rich medium (YPG-medium) under growing conditions, but not when ...
openaire   +3 more sources

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