Results 71 to 80 of about 260,779 (356)
Engineering orthogonal dual transcription factors for multi-input synthetic promoters [PDF]
, 2016 Synthetic biology has seen an explosive growth in the capability of engineering artificial gene circuits from transcription factors (TFs), particularly in bacteria. However, most artificial networks still employ the same core set of TFs (for example LacI,
Broedel, AK, Isalan, M, Jaramillo, A
core +2 more sources
Genetic Influence on Gonadotropic Activity in Mice1 [PDF]
Biology of Reproduction, 1971 Mice differing at a single genetic locus, pink-eyed dilution (p) release different numbers of ova in response to exogenous gonadotropic stimulation. The presence of pink-eyed dilution (p) or of its allele P-unstable (p”) in the genotype of the mouse generally increases the number of ova released in response to injections of pregnant mare’s serum (PMS ...
openaire +3 more sources
FEBS Letters, EarlyView.The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source
Conserved mosquito/parasite interactions affect development of Plasmodium falciparum in Africa. [PDF]
PLoS Pathogens, 2008 In much of sub-Saharan Africa, the mosquito Anopheles gambiae is the main vector of the major human malaria parasite, Plasmodium falciparum. Convenient laboratory studies have identified mosquito genes that affect positively or negatively the ...
Antonio M Mendes +9 more
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Autism: genetics, environmental stressors, maternal immune activation, and the male bias in autism [PDF]
, 2022 Sarah Otaru, David A. Lawrence
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FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Residue K28 of Zika Virus NS5 Protein Is Implicated in Virus Replication and Antagonism of STAT2
MicroorganismsThe identification of four potential nonstructural 5 (NS5) residues—K28, K45, V335, and S749—that share the same amino acid preference in STAT2-interacting flaviviruses [Dengue virus (DENV) and Zika virus (ZIKV)], but not in STAT2-non-interacting ...
Nias Y. G. Peng +3 more
doaj +1 more source
CRISPR/Cas9 Mediated Genome Engineering for Improvement of Horticultural Crops
Frontiers in Plant Science, 2017 Horticultural crops are an important part of agriculture for food as well as nutritional security. However, several pests and diseases along with adverse abiotic environmental factors pose a severe threat to these crops by affecting their quality and ...
Suhas G. Karkute +4 more
doaj +1 more source
Mutant and chimeric recobinant plasminogen activatorsproduction in eukaryotic cellsand preliminary characterization [PDF]
, 1987 Mutant urokinase-type plasminogen activator (u-PA) genes and hybrid genes between tissue-type plasminogen activator (t-PA) and u-PA have been designed to direct the synthesis of new plasminogen activators and to investigate the structure-function ...
Andre, B. +11 more
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Accurate timekeeping is controlled by a cycling activator in Arabidopsis. [PDF]
, 2013 Transcriptional feedback loops are key to circadian clock function in many organisms. Current models of the Arabidopsis circadian network consist of several coupled feedback loops composed almost exclusively of transcriptional repressors.
Devisetty, Upendra K +2 more
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