Results 181 to 190 of about 14,005,924 (265)

Advisory Group Conference, Prepaid Dental Plan Research Study

Operations Research ...
Dean, Burton V. (Creatorcre)
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Projecting the Impact and Costs of Near Point-of-Care Tuberculosis Screening Assays in Community-based Active Case Finding. [PDF]

Clin Infect Dis
Andrews JR, Kendall EA, Cattamanchi A, Denkinger CM, Nahid P, Shrestha S, Marx FM, Dowdy D, Hermans S, Cobelens F.   +9 more
europepmc   +1 more source

Allocation of Resources for Basic Research in a Mission Oriented Governmental Agency

Operations Research ...
Brown, Melvin (Creatorcre), Huettner, David (Creatorcre), Mantel, Samuel J. (Creatorcre), Friedel, Donald C. (Creatorcre), Dean, Burton V. (Creatorcre)   +4 more
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Routine active case finding in Nigerian penitentiary institutions: comparing yields from digital X-ray with CAD4TB and WHO 4-symptom screening. [PDF]

BMC Infect Dis
Chukwuogo O, Odume B, Ugochukwu L, Ogbudebe C, Chukwu E, Useni S, Nwokoye N, Sheshi M, Nongo D, Ihesie A, Eneogu R, Ubochioma E.   +11 more
europepmc   +1 more source

Application of Pert in Plant Construction Scheduling in the Ohio Brass Company

Operations Research ...
Mathis, Samuel J., Jr. (Creatorcre), Huckfeldt, Vaughn E. (Creatorcre), Dean, Burton V. (Creatorcre)   +2 more
core  

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Analysis of Congestion Problems in UCDF Operations

Operations Research ...
Hartman, James K. (Creatorcre)
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source