Results 91 to 100 of about 3,324,854 (290)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Application of Active Magnetic Ranging Technology in Capping Operation of Well T1

open access: yesShiyou jixie, 2022
The active magnetic ranging technology is mainly used to solve the problem of effective connection between relief well and failure well, and there is no corresponding equipment in China.
Che Yang   +6 more
doaj  

Chemical stability of chlorine dioxide in the presence of prochloraz manganese

open access: yesPlant Protection Science, 2019
The chemical stability of chlorine dioxide (ClO2) in the presence of prochloraz manganese (prochloraz-Mn) as biologically active substances used in agrochemical treatments in the cultivation of mushrooms are presented.
Arkadiusz Chruściel   +3 more
doaj   +1 more source

Making the Case for Active Living Communities

open access: yesAmerican Journal of Public Health, 2003
At first glance, a dearth of sidewalks may not seem like a significant public health concern. However, the disappearance of sidewalks is one of many environmental barriers to active living that transform the health of American communities in powerful ways.
Risa, Lavizzo-Mourey   +1 more
openaire   +3 more sources

Multikernel Activation Functions: Formulation and a Case Study [PDF]

open access: yes, 2019
The design of activation functions is a growing research area in the field of neural networks. In particular, instead of using fixed point-wise functions (e.g., the rectified linear unit), several authors have proposed ways of learning these functions directly from the data in a non-parametric fashion.
Simone Scardapane   +3 more
openaire   +3 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

The use of soluble packer plugs during repair and insulation work in oil wells

open access: yesИзвестия высших учебных заведений: Нефть и газ
Most oil and gas fields in the Russian Federation are currently in a late stage of development. This stage includes declining production rates, decreasing reservoir pressures, and in-creasing water cut, which in turn requires repair and isolation ...
D. S. Leontiev   +3 more
doaj   +1 more source

Casing and liners for drilling and completion /

open access: yes, 2007
The Gulf Drilling Series is a joint project between Gulf Publishing Company and the International Association of Drilling Contractors. The first text in this Series presents casing design and mechanics in a concise, two-part format.
Byrom, Ted G.
core  

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