Results 81 to 90 of about 3,324,854 (290)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Известия Томского политехнического университета: Инжиниринг георесурсовRelevance. Recently, ESG (Environment, Social, Governance) principles have been given an important role in the agenda of oil and gas companies – this is an actively developing global trend in the modern business environment.
Ruslan Z. Akchurin +5 more
doaj +1 more source
Casing design : theory and practice /
, 1995 Casing design has followed an evolutionary trend and most improvements have been made due to the advancement of technology. Contributions to the technology in casing design have come from fundamental research and field tests, which have made casing safe ...
Chilingar, George V. +1 more
core
NUMERICAL SIMULATION OF HYDRAULICALLY INDUCED CASING DEFORMATION IN SHALE RESERVOIR [PDF]
, 2018 Hydraulic fracturing stimulation is widely conducted to enhance hydrocarbon production in low-permeability reservoirs. However, the massive fracturing can lead to the well failure by compromising well integrity.
Xu, Ziyi
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Journal of Petroleum Exploration and Production TechnologyCasing deformation in ultra-deep, high‑sulfur gas fields poses a critical threat to wellbore integrity and safe production. This study investigates this problem in the Yuanba Gas Field (Sichuan Basin, burial depth 6500–7100 m, H₂S up to 13.37%) by ...
Zheng Kang +6 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Development and Application of Hydraulic Control Gas Lift Mandrel
Shiyou jixie, 2017 To address the issue of continuous gas lift string with conventional gas lift valve being unable to build casing pressure, a hydraulic control mandrel has been developed.
Gao Xiang +4 more
doaj
Average-Case Active Learning with Costs [PDF]
, 2009 14 pages, 2 ...
Andrew Guillory, Jeff A. Bilmes
openaire +3 more sources